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1 trials

Recent Start date Enrollment

Phase 1 × Advanced Cancer × olaparib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Conditions

Breast Neoplasms 21 Ovarian Neoplasms 13 Neoplasm Metastasis 11 Prostatic Neoplasms 8 Neoplasms 8 Pancreatic Neoplasms 7 Triple Negative Breast Neoplasms 6 Squamous Cell Carcinoma of Head and Neck 4 Advanced Solid Tumors 4 Small Cell Lung Carcinoma 3 Recurrence 3 Head and Neck Neoplasms 3 Fallopian Tube Neoplasms 3 Carcinoma, Squamous Cell 3 Solid Tumors 2 Sarcoma 2 Neuroendocrine Tumors 2 Lymphoma 2 Hodgkin Disease 2 Fanconi Anemia, Complementation Group D1 2 Endometrial Neoplasms 2 Advanced Solid Tumours 2 Advanced Solid Tumor 2 Triple Negative Metastatic Breast Cancer 1 Thymoma 1 Thrombocytosis 1 Solid Tumor 1 Smoking 1 Sarcoma, Ewing 1 Rhabdomyosarcoma 1

Interventions

Nivolumab 6 Bevacizumab 5 temsirolimus 4 Sirolimus 4 Paclitaxel 4 Docetaxel 4 Pemetrexed 3 Ipilimumab 3 Erlotinib Hydrochloride 3 Carboplatin 3 ARRY-334543 3 apatinib 2 abemaciclib 2 Vorinostat 2 Sunitinib 2 Magnetic Resonance Spectroscopy 2 Gemcitabine 2 Everolimus 2 Chlorogenic Acid 2 Cetuximab 2 6-(6-(1-methyl-1H-pyrazol-4-yl)-(1,2,4)triazolo(4,3-b)pyridazin-3-ylsulfanyl)quinoline 2 vorolanib 1 vistusertib 1 trametinib 1 tislelizumab 1 tilsotolimod 1 sargramostim 1 regorafenib 1 ralimetinib 1 prexasertib 1

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT02338622 2024-09-26

ComPAKT

Royal Marsden NHS Foundation Trust

Phase 1 Completed

Advanced Cancer

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