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Phase 1 × Advanced Cancer × trametinib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Conditions

Melanoma 19 Neoplasms 17 Carcinoma, Non-Small-Cell Lung 9 Neoplasm Metastasis 8 Colorectal Neoplasms 8 Pancreatic Neoplasms 7 Rectal Neoplasms 4 Triple Negative Breast Neoplasms 3 Lung Neoplasms 3 Colonic Neoplasms 3 Thyroid Neoplasms 2 Multiple Myeloma 2 Meningioma 2 Glioma 2 Breast Neoplasms 2 Brain Neoplasms 2 Adenocarcinoma of Lung 2 Thyroid Carcinoma, Anaplastic 1 Thrombocytosis 1 Squamous Cell Carcinoma of Head and Neck 1 Solid Tumors 1 Solid Tumor Cancer 1 Solid Tumor 1 Sarcoma 1 Rhabdoid Tumor 1 Relapsed Metastatic KRAS-Mutated Non-Small Cell Lung Cancer 1 Recurrence 1 Pyloric Stenosis, Hypertrophic 1 Prostatic Neoplasms 1 Primary Myelofibrosis 1

Interventions

Nivolumab 6 Bevacizumab 5 temsirolimus 4 Sirolimus 4 Paclitaxel 4 Docetaxel 4 Pemetrexed 3 Ipilimumab 3 Erlotinib Hydrochloride 3 Carboplatin 3 apatinib 2 abemaciclib 2 Vorinostat 2 Magnetic Resonance Spectroscopy 2 Gemcitabine 2 Everolimus 2 Chlorogenic Acid 2 Cetuximab 2 ARRY-334543 2 6-(6-(1-methyl-1H-pyrazol-4-yl)-(1,2,4)triazolo(4,3-b)pyridazin-3-ylsulfanyl)quinoline 2 vorolanib 1 vistusertib 1 trametinib 1 tislelizumab 1 tilsotolimod 1 sargramostim 1 regorafenib 1 ralimetinib 1 pazopanib 1 palifosfamide lysine 1

Date Range

30 days 90 days 1 year All

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Has results Has announcements

NCT01287546 2017-02-15

A Study of LY2875358 in Participants With Advanced Cancer

Eli Lilly and Company

Phase 1 Completed

Advanced Cancer

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