Clinical Trials Browser

NCT06369259 2026-02-11

Open-label Phase 2 Study of Avutometinib (RAF/MEK Clamp) in Combination With Defactinib (FAK Inhibitor) and Cetuximab in Patients With Unresectable, Anti-EGFR-Refractory Advanced Colorectal Cancer

Phase 2 Recruiting

33 enrolled

Gastrointestinal

Advanced Colorectal Cancer

NCT07391618 2026-02-06

Clinical Study on the First-line Treatment of Advanced Colorectal Cancer With Simultaneous Infusion of Levozolinate for Injection and 5-FU

Phase 2 Recruiting

583 enrolled

Gastrointestinal

Advanced Colorectal Cancer

NCT07281157 2025-12-30

Irinotecan Liposome Plus Capecitabine and Enronsubemab Combined With Short-course Radiotherapy for Neoadjuvant Treatment of Locally Advanced Rectal Cancer

Phase 2 Recruiting

30 enrolled

Gastrointestinal

Advanced Colorectal Cancer

NCT06885385 2025-06-24

A Phase 2 Study Evaluating the Safety and Efficacy of JS207 With or Without JS015 in Combination With Chemotherapy in Patients With Colorectal Cancer

Phase 2 Recruiting

60 enrolled

Gastrointestinal

Advanced Colorectal Cancer

NCT07000305 2025-06-02

SUPβORT

Phase 2 Not yet recruiting

42 enrolled

Gastrointestinal

Advanced Colorectal Cancer

NCT06838546 2025-02-20

A Multicenter, Open Phase IIb Clinical Study to Evaluate the Efficacy and Safety of B1962 Injection in the Treatment of Advanced Colorectal Cancer

Phase 2 Not yet recruiting

80 enrolled

Gastrointestinal

Advanced Colorectal Cancer

NCT02619435 2023-03-24

STREAM

Phase 2 Unknown

46 enrolled

Gastrointestinal

Advanced Colorectal Cancer

NCT05364489 2022-05-20

Efficacy, Safety and Exploratory Clinical Study of Bevacizumab Combined With Oxaliplatin and TAS-102 in First-line Treatment of Advanced Colorectal Cancer

Phase 2 Not yet recruiting

20 enrolled

Gastrointestinal

Advanced Colorectal Cancer

NCT04764006 2021-11-04

Surufatinib Combined With Sintilimab for Advanced MSS-Type Colorectal Cancer : a Phase II Study

Phase 2 Unknown

10 enrolled

Gastrointestinal

Advanced Colorectal Cancer

NCT03126071 2021-08-30

Raltitrexed-based Chemotherapy Plus Bevacizumab in Retreated Patients With Advanced Colorectal Cancer

Phase 2 Unknown

100 enrolled

Gastrointestinal

Advanced Colorectal Cancer

NCT04324476 2021-08-30

A Study of Bevacizumab Plus XELOX/XELIRI for First-line Treatment in Unresectable Advanced Colorectal Cancer

Phase 2 Unknown

50 enrolled

Gastrointestinal

Advanced Colorectal Cancer

NCT02227667 2021-06-18

Evaluate the Efficacy of MEDI4736 in Immunological Subsets of Advanced Colorectal Cancer

Phase 2 Completed

16 enrolled 9 charts

Gastrointestinal

Advanced Colorectal Cancer

NCT03311750 2021-06-07

A-REPEAT

Phase 2 Terminated

23 enrolled

Gastrointestinal

Advanced Colorectal Cancer

NCT03427268 2021-05-24

Clinical Trial of PM60184 in Advanced Colorectal Cancer After Standard Treatment

Phase 2 Completed

32 enrolled 22 charts

Gastrointestinal

Advanced Colorectal Cancer

NCT04734249 2021-02-02

Second-line Surufatinib Combined With Chemotherapy in Advanced CRC

Phase 2 Unknown

56 enrolled

Gastrointestinal

Advanced Colorectal Cancer

NCT00637091 2021-01-22

Efficacy Analysis of Cetuximab Plus Irinotecan in Patients With Wild-type KRAS Without Regard to Epidermal Growth Factor Receptor (EGFR) Expressions

Phase 2 Completed

40 enrolled

Gastrointestinal

Advanced Colorectal Cancer

NCT00309179 2017-09-14

A Phase II Study of the Safety and Efficacy of E7820 Plus Cetuximab in Colorectal Cancer, Preceded by a Run-in Study in Advanced Solid Tumors

Phase 2 Completed

41 enrolled

Gastrointestinal

Advanced Colorectal Cancer

NCT00824161 2012-04-23

Phase II Study of TAS-109 to Treat Advanced Colorectal Cancer

Phase 2 Terminated

28 enrolled 8 charts

Gastrointestinal

Advanced Colorectal Cancer

NCT00972465 2009-09-07

Study of Nimotuzumab to Treat Colorectal Cancer

Phase 2 Unknown

48 enrolled

Gastrointestinal

Advanced Colorectal Cancer

NCT00286000 2007-12-28

High Dose Simplified Folfiri in Advanced Colorectal Cancer: a Multicentre Phase II Study

Phase 2 Completed

106 enrolled

Gastrointestinal

Advanced Colorectal Cancer