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Phase 1 × Advanced Solid Tumors × adavosertib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Other solid neoplasm 1

Conditions

Advanced Solid Tumours 4 Squamous Cell Carcinoma of Head and Neck 2 Small Cell Lung Carcinoma 2 Ovarian Neoplasms 2 Leukemia, Myeloid, Acute 2 Glioblastoma 2 Vaginal Neoplasms 1 Uterine Cervical Neoplasms 1 Triple Negative Breast Neoplasms 1 Stomach Neoplasms 1 Solid Tumors 1 Neoplasm Metastasis 1 Myelodysplastic Syndromes 1 Muscle Invasive Bladder Cancer 1 Meningeal Carcinomatosis 1 Leukemia, Myelogenous, Chronic, BCR-ABL Positive 1 Laryngeal Neoplasms 1 Head and Neck Neoplasms 1 Gliosarcoma 1 Esophageal Squamous Cell Carcinoma 1 Esophageal Neoplasms 1 Diffuse Intrinsic Pontine Glioma 1 Colorectal Neoplasms 1 Carcinoma, Endometrioid 1 Brain Neoplasms 1 Blast Crisis 1 Astrocytoma 1 Advanced Solid Tumors 1 Adenocarcinoma Of Esophagus 1

Interventions

Injections 15 Carboplatin 14 Docetaxel 10 pembrolizumab 7 durvalumab 6 Cisplatin 6 linifanib 5 Paclitaxel 5 talazoparib 4 olaparib 4 Panobinostat 4 Nivolumab 4 Itraconazole 4 Bevacizumab 4 zimberelimab 3 sintilimab 3 depatuxizumab 3 atezolizumab 3 ST 1481 3 S 1 (combination) 3 Rifampin 3 Pemetrexed 3 Fluorouracil 3 trifluridine tipiracil drug combination 2 tremelimumab 2 tislelizumab 2 tesetaxel 2 spartalizumab 2 motesanib diphosphate 2 ixabepilone 2

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT05008913 2022-09-06

ADME

AstraZeneca

Phase 1 Terminated

Other solid neoplasm

Advanced Solid Tumors

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