Clinical Trials Browser

Phase 2 × Interventional × Arthritis, Rheumatoid × Clear all

NCT07137598 2026-03-06

A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)

Phase 2 Recruiting

160 enrolled

Arthritis, Rheumatoid

NCT01242488 2024-07-17

Efficacy and Safety of CDP6038 in Patients With Rheumatoid Arthritis With an Unsuccessful Response to Anti-Tumor Necrosis Factor (Anti-TNF) Therapy

Phase 2 Completed

221 enrolled

Arthritis, Rheumatoid

NCT00048321 2022-12-05

ISIS 104838, an Inhibitor of Tumor Necrosis Factor, for Active Rheumatoid Arthritis

Phase 2 Completed

160 enrolled

Arthritis, Rheumatoid

NCT02538341 2021-11-23

Safety and Effectiveness of Live Zoster Vaccine in Anti-Tumor Necrosis Factor (TNF) Users (VERVE Trial)

Phase 2 Completed

617 enrolled 17 charts

Arthritis, Arthritis, Rheumatoid, Crohn Disease, Psoriasis, Spondylitis, Ankylosing, Arthritis, Psoriatic

NCT01960855 2021-08-24

A Study Investigating the Efficacy and Safety of ABT-494 Given With Methotrexate in Subjects With Rheumatoid Arthritis Who Failed Anti-Tumor Necrosis Factor (TNF) Biologic Therapy

Phase 2 Completed

276 enrolled 14 charts

Arthritis, Arthritis, Rheumatoid, Joint Diseases, Musculoskeletal Diseases

NCT03001219 2020-01-29

A Study of RO7123520 to Evaluate the Safety and Efficacy in Participants With Moderately To Severely Active Rheumatoid Arthritis (RA) Who Are Inadequately Responding to Anti-Tumor Necrosis Factor (TNF)-Alpha Therapy

Phase 2 Terminated

109 enrolled 24 charts

Arthritis, Rheumatoid

NCT02102594 2019-12-03

TAVAB

Phase 2 Terminated

11 enrolled

Arthritis, Rheumatoid, Lupus Erythematosus, Systemic, Myasthenia Gravis

NCT02882087 2019-04-03

A Study of the Efficacy and Safety of TACI-antibody Fusion Protein Injection (RC18) in Subjects With Inadequate Response to TNF-α Antagonists Due to Treat Moderate and Severe Rheumatoid Arthritis

Phase 2 Terminated

60 enrolled

Lymphoid

Arthritis, Rheumatoid, Lymphoma, Follicular

NCT00094562 2019-01-18

A Fish Oil Supplement to Maintain Body Weight in Patients With Disease-Related Weight Loss

Phase 2 Completed

25 enrolled

Arthritis, Rheumatoid, Neoplasms, Weight Loss, Pulmonary Disease, Chronic Obstructive

NCT02862574 2018-06-27

Andecaliximab as Add-On Therapy to a Tumor Necrosis Factor Inhibitor and Methotrexate Regimen in Adults With Moderately to Severely Active Rheumatoid Arthritis

Phase 2 Terminated

15 enrolled 11 charts

Arthritis, Rheumatoid

NCT01715896 2016-10-31

A Study of Mavrilimumab Versus Anti Tumor Necrosis Factor in Subjects With Rheumatoid Arthritis

Phase 2 Completed

215 enrolled 37 charts

Arthritis, Rheumatoid

NCT01390545 2016-04-13

VELVET

Phase 2 Terminated

300 enrolled

Arthritis, Rheumatoid

NCT01463059 2013-03-25

Efficacy and Safety of Olokizumab With Rheumatoid Arthritis With Previously Failed to Anti-tumor Necrosis Factor (Anti-TNF) Therapy

Phase 2 Completed

119 enrolled

Arthritis, Rheumatoid

NCT00537667 2009-11-26

The SPECTRA Study

Phase 2 Terminated

22 enrolled

Arthritis, Rheumatoid, Inflammation