Clinical Trials

59 enrolled 20 charts

CNSLymphoid

Astrocytoma, Brain Neoplasms, Glioma, Lymphoma, Central Nervous System Neoplasms

NCT01553149 2025-01-07

Low-Dose or High-Dose Lenalidomide in Treating Younger Patients With Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway Glioma

75 enrolled 17 charts

Astrocytoma, Neurofibromatosis 1, Optic Nerve Glioma

NCT02530320 2024-11-22

Safety and Efficacy of PD0332991 (Palbociclib), a Cyclin-dependent Kinase 4 and 6 Inhibitor, in Patients With Oligodendroglioma or Recurrent Oligoastrocytoma Anaplastic With the Activity of the Protein RB Preserved

34 enrolled 13 charts

Astrocytoma, Oligodendroglioma

NCT00114140 2024-07-08

Temozolomide and Radiation Therapy in Treating Patients With Gliomas

136 enrolled 9 charts

Astrocytoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT03043391 2024-04-08

Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children

8 enrolled 9 charts

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Oligodendroglioma, Gliosarcoma

NCT00445965 2024-04-04

Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer

CNSDermatologicGynecologicOther solid neoplasmSarcomaThoracic

78 enrolled 11 charts

Familial ependymoma, Uveal Melanoma, Astrocytoma, Brain Neoplasms, Chondrosarcoma, Ependymoma, Glioblastoma, Glioma, Lung Neoplasms, Medulloblastoma, Melanoma, Neoplasm Metastasis, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Glioma, Subependymal, Gliosarcoma, Rhabdoid Tumor, Optic Nerve Glioma, Small Cell Lung Carcinoma, Desmoplastic Small Round Cell Tumor

NCT00589875 2024-04-03

BrTK02

52 enrolled 10 charts

Astrocytoma, Glioblastoma, Glioma

NCT01236560 2024-02-20

Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade Glioma

Phase 2/3 Completed

101 enrolled 15 charts

Astrocytoma, Spinal Cord Neoplasms

NCT01922076 2024-01-31

Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas

46 enrolled 20 charts

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Gliosarcoma

NCT02684058 2023-12-13

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors

151 enrolled 45 charts 1 FDA

CNSOther hematologic neoplasmSarcoma

Astrocytoma, Ganglioneuroma, Glioblastoma, Glioma, Oligodendroglioma, Ganglioglioma, Neurocytoma

NCT03149003 2023-11-15

A Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapy

Phase 3 Completed

221 enrolled 17 charts

CNSGenitourinary

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Wilms Tumor

NCT03538587 2023-08-01

Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their Caregivers

Phase NA Completed

10 enrolled 16 charts

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Leukemia, Sarcoma

NCT01290692 2023-07-03

Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma

14 enrolled 11 charts

Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Glioblastoma, Glioma, Neoplasms, Nervous System Diseases, Nervous System Neoplasms, Central Nervous System Neoplasms

NCT01466686 2023-07-03

Low Dose Radiation Therapy for Glioblastoma Multiforme

31 enrolled 11 charts

Astrocytoma, Glioblastoma, Glioma

NCT03032484 2023-06-15

TVB- 2640 in Combination With Bevacizumab in Patients With First Relapse of High Grade Astrocytoma

25 enrolled 9 charts

Astrocytoma

NCT01081223 2023-06-01

Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV Glioma

12 enrolled 11 charts

Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Glioblastoma, Glioma, Neoplasms, Nervous System Diseases, Nervous System Neoplasms, Central Nervous System Neoplasms

NCT00100802 2023-02-15

Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas

118 enrolled 8 charts

Astrocytoma, Glioblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Gliosarcoma

NCT00003458 2022-03-07

Antineoplaston Therapy in Treating Children With Brain Tumors

34 enrolled 6 charts

Astrocytoma, Craniopharyngioma, Glioblastoma, Oligodendroglioma, Neuroectodermal Tumors, Primitive, Ganglioglioma, Neurocytoma, Gliosarcoma

NCT01189266 2021-10-28

Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma

79 enrolled 17 charts

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Gliosarcoma

NCT00369785 2021-10-20

Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors

Phase 3 Completed

198 enrolled 10 charts

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Ependymoma, Fatigue, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasm Metastasis, Oligodendroglioma, Pinealoma, Radiation Injuries, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT02015819 2021-10-20

Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas

16 enrolled 16 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Gliosarcoma

NCT01032200 2021-09-28

Armodafinil in Treating Fatigue Caused By Radiation Therapy in Patients With Primary Brain Tumors

54 enrolled 14 charts

Astrocytoma, Brain Neoplasms, Cognition Disorders, Ependymoma, Fatigue, Glioblastoma, Glioma, Meningioma, Nervous System Neoplasms, Oligodendroglioma, Glioma, Subependymal, Gliosarcoma

NCT01346267 2021-08-18

SCUSF1202

Phase NA Completed

187 enrolled 5 charts

Astrocytoma, Meningioma, Nausea, Oligodendroglioma, Vomiting, Central Nervous System Neoplasms, Choroid Plexus Neoplasms

NCT00879437 2021-07-21

Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma

38 enrolled 53 charts

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neuroepithelial, Gliosarcoma

NCT01635283 2020-11-04

Vaccine for Patients With Newly Diagnosed or Recurrent Low-Grade Glioma

5 enrolled 6 charts

Astrocytoma, Brain Neoplasms, Glioma, Oligodendroglioma

NCT00823459 2020-07-28

Everolimus in Treating Patients With Recurrent Low-Grade Glioma

58 enrolled 10 charts

Astrocytoma, Brain Neoplasms, Glioma, Oligodendroglioma

NCT00795665 2020-05-12

Bevacizumab and Carmustine in Treating Patients With Relapsed or Progressive High-Grade Glioma

7 enrolled 4 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT02529072 2020-03-26

AVERT

6 enrolled 11 charts

Astrocytoma, Glioblastoma, Glioma

NCT00553150 2020-02-13

Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

122 enrolled 11 charts

Astrocytoma, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00337207 2020-02-07

Bevacizumab in Treating Patients With Recurrent or Progressive Glioma

55 enrolled 10 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00390299 2020-01-02

Viral Therapy in Treating Patients With Recurrent Glioblastoma Multiforme

23 enrolled 15 charts

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT00892177 2019-10-21

Dasatinib and Bevacizumab in Treating Patients With Recurrent or Progressive High-Grade Glioma or Glioblastoma Multiforme

144 enrolled 14 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT00004259 2019-09-12

Radiation Therapy Combined With Chemotherapy in Treating Patients With Anaplastic Astrocytoma or Mixed Gliomas

Phase 3 Completed

230 enrolled 14 charts

Astrocytoma, Glioma, Central Nervous System Neoplasms

NCT00238264 2019-08-07

Radiation Therapy in Treating Young Patients With Gliomas

92 enrolled 12 charts

Astrocytoma, Brain Neoplasms, Oligodendroglioma, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT00404248 2019-03-06

Tetra-O-Methyl Nordihydroguaiaretic Acid in Treating Patients With Recurrent High-Grade Glioma

35 enrolled 13 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00313729 2019-02-07

Temozolomide in Treating Patients With Low-Grade Glioma

120 enrolled 8 charts

Phase EARLY_PHASE1 Completed

Astrocytoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00452868 2018-09-07

Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain

14 enrolled 7 charts

Familial ependymoma, Astrocytoma, Medulloblastoma, Radiation Injuries, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neurotoxicity Syndromes, Optic Nerve Glioma

NCT00058123 2018-08-21

Poly-ICLC in Treating Patients With Recurrent or Progressive Anaplastic Glioma

55 enrolled 8 charts

Astrocytoma, Brain Neoplasms, Ependymoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00782626 2018-08-15

Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas

23 enrolled 6 charts

Astrocytoma, Glioma

NCT00679354 2018-08-01

Cilengitide in Treating Younger Patients With Recurrent or Progressive High-Grade Glioma That Has Not Responded to Standard Therapy

30 enrolled 19 charts

Astrocytoma, Oligodendroglioma, Optic Nerve Glioma

NCT01648348 2018-05-23

Bevacizumab With or Without Anti-Endoglin Monoclonal Antibody TRC105 in Treating Patients With Recurrent Glioblastoma Multiforme

116 enrolled 17 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT00841555 2018-04-18

Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Astrocytoma

9 enrolled 10 charts