Clinical Trials Browser

OTHER × Astrocytoma × Temozolomide × Clear all

NCT05843253 2026-03-04

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Phase 2 Recruiting

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT04623931 2026-01-14

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

Phase 2 Recruiting

Astrocytoma, Glioblastoma, Oligodendroglioma

NCT05236036 2026-01-14

Mycophenolate Mofetil in Combination With Standard of Care for the Treatment of Glioblastoma

Phase 1 Active not recruiting

Astrocytoma, Glioblastoma

NCT07223034 2025-11-04

A Study of 177Lu-PSMA-617 in People With Gliomas

Phase 1 Recruiting

Astrocytoma, Glioblastoma, Glioma

NCT07215910 2025-10-14

Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

Phase 3 Not yet recruiting

Astrocytoma, Lymphoma, Follicular

NCT03180502 2025-07-11

Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

Phase 2 Active not recruiting

Astrocytoma, Glioma, Oligodendroglioma

NCT05698524 2025-05-20

A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma

Phase 1 Recruiting

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT01837862 2024-07-05

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas

Phase 1/2 Completed

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma, Gliosarcoma, Optic Nerve Glioma

NCT06283927 2024-02-28

RECSUR

Astrocytoma, Glioblastoma

NCT02168270 2023-11-24

Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade Glioma

Phase 1 Terminated

4 enrolled 6 charts

Astrocytoma, Glioblastoma, Oligodendroglioma, Gliosarcoma

NCT01466686 2023-07-03

Low Dose Radiation Therapy for Glioblastoma Multiforme

Phase 2 Completed

31 enrolled 11 charts

Astrocytoma, Glioblastoma, Glioma

NCT02023905 2022-12-29

Everolimus With and Without Temozolomide in Adult Low Grade Glioma

Phase 2 Terminated

27 enrolled 15 charts

Astrocytoma, Oligodendroglioma

NCT03243461 2022-06-06

HIT-HGG-2013

Phase 3 Unknown

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neuroepithelial

NCT01110876 2021-08-25

Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM)

Phase 1/2 Terminated

21 enrolled 8 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT01649830 2020-05-28

Efficacy of Post-radiation Adjuvant Temozolomide Chemotherapy in Residue Low-grade Glioma

Phase 3 Recruiting

Astrocytoma, Oligodendroglioma

NCT00756106 2020-05-13

MRI Scans in Evaluating the Effects of Radiation Therapy and Chemotherapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Glioma

Phase NA Terminated

15 enrolled 6 charts

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT04105374 2020-03-24

Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed Glioblastoma

Phase 2/3 Withdrawn

Astrocytoma, Glioblastoma, Oligodendroglioma

NCT01478321 2020-03-12

Efficacy of Hypofractionated XRT w/Bev. + Temozolomide for Recurrent Gliomas

Phase 2 Terminated

54 enrolled 10 charts

Astrocytoma, Ependymoma, Glioblastoma, Oligodendroglioma

NCT00275067 2020-02-25

Arsenic Trioxide, Temozolomide, and Radiation Therapy in Treating Patients With Malignant Glioma That Has Been Removed By Surgery

Phase 1/2 Unknown

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00553150 2020-02-13

Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Phase 1/2 Completed

122 enrolled 11 charts

Astrocytoma, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01480050 2019-05-22

Mibefradil Dihydrochloride and Temozolomide in Treating Patients With Recurrent Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT02209428 2019-02-21

A Prospective Cohort to Study the Effect of Temozolomide on IDH Mutational Low Grade Gliomas

Phase 2 Unknown

Astrocytoma, Oligodendroglioma

NCT01044966 2019-02-12

A Study of Intraventricular Liposomal Encapsulated Ara-C (DepoCyt) in Patients With Recurrent Glioblastoma

Phase 1/2 Terminated

12 enrolled 12 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT00313729 2019-02-07

Temozolomide in Treating Patients With Low-Grade Glioma

Phase 2 Completed

120 enrolled 8 charts

Astrocytoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT01868906 2018-08-24

FMISOPETSCS

Phase 2 Terminated

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT03633552 2018-08-16

Efficacy of Two Temozolomide Regimens in Adjuvant Treatment of Patients With Brain High Grade Glioma

Phase 3 Unknown

Astrocytoma, Glioblastoma

NCT00471653 2018-07-09

Pharmacokinetics in Patients With Newly Diagnosed High-Grade Glioma Receiving Temozolomide and Radiation Therapy

CNSClassical hematologySarcoma

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Thrombocytopenia, Central Nervous System Neoplasms, Gliosarcoma

NCT00003176 2018-06-27

Temozolomide and Carmustine in Treating Patients With Anaplastic Glioma

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00006025 2018-06-27

Temozolomide Plus Irinotecan in Treating Patients With Recurrent Malignant Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00027625 2018-06-27

Gefitinib Plus Temozolomide in Treating Patients With Malignant Primary Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00841555 2018-04-18

Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Astrocytoma

Phase 1 Completed

9 enrolled 10 charts

Astrocytoma, Glioblastoma, Gliosarcoma

NCT01765088 2018-02-23

A Phase III Trial on Adjuvant Temozolomide With or Without Interferon-alpha in Newly Diagnosed High-grade Gliomas

Phase 3 Unknown

Astrocytoma, Glioblastoma, Glioma

NCT00619112 2018-01-31

Temozolomide in Treating Patients With Recurrent High-Grade Glioma

Phase 2 Completed

60 enrolled 9 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00362570 2017-11-30

Temozolomide in Patients With Newly Diagnosed Anaplastic Oligodendroglioma and Mixed Oligoastrocytoma

Phase 2 Completed

Astrocytoma, Oligodendroglioma

NCT02039778 2017-06-05

STRONG

Phase NA Terminated

4 enrolled 8 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT02976441 2017-02-20

Autologous Stem Cell Collection and Reinfusion in Newly Diagnosed High Grade Gliomas

Phase EARLY_PHASE1 Withdrawn

Astrocytoma, Ependymoma, Glioma, Oligodendroglioma, Optic Nerve Glioma

NCT00498927 2016-02-29

Temozolomide in Treating Patients With Recurrent Glioblastoma Multiforme or Other Malignant Glioma

Phase 2 Completed

47 enrolled 7 charts

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Glioma, Subependymal, Gliosarcoma

NCT00006263 2015-08-05

Carboplatin, Temozolomide, and Filgrastim in Treating Patients With Newly Diagnosed or Recurrent High-Grade Glioma

Phase 2 Withdrawn

Astrocytoma, Glioblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT01517776 2015-07-21

HGG-CilMetro

Phase 2 Terminated

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma, Recurrence

NCT00005951 2014-08-22

Irinotecan Plus Temozolomide in Treating Patients With Recurrent Primary Malignant Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00616005 2014-08-18

Ph. II Treatment of Adults w Primary Malignant Glioma w Irinotecan + Temozolomide

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT00897377 2014-08-05

Treatment Strategy for Low-grade Gliomas

Phase 3 Terminated

Astrocytoma, Oligodendroglioma

NCT00003466 2014-07-09

Temozolomide in Treating Patients With Progressive Low-Grade Glioma

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Glioma, Subependymal, Optic Nerve Glioma

NCT00575887 2013-12-20

Efficacy of Protracted Temozolomide in Patients With Progressive High Grade Glioma

Phase 2 Completed

25 enrolled 5 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma

NCT00610571 2013-10-25

Ph I Oral Topotecan and Temozolomide for Patients With Malignant Gliomas

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT00005952 2013-06-20

Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors

Phase 1/2 Completed

CNSGenitourinaryGynecologicHead & NeckSarcoma

Familial ependymoma, Testicular Germ Cell Tumor, Astrocytoma, Head and Neck Neoplasms, Kidney Neoplasms, Medulloblastoma, Nasopharyngeal Neoplasms, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

NCT00005955 2013-06-20

Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors

Phase 2 Completed

Astrocytoma, Neuroblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms

NCT00006474 2013-06-20

Temozolomide and O6-benzylguanine in Treating Patients With Newly Diagnosed, Recurrent, or Progressive Anaplastic Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00004113 2013-06-19

Temozolomide in Treating Patients With Recurrent Malignant Glioma

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00354068 2013-03-28

Imatinib Mesylate and Temozolomide in Treating Patients With Malignant Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma