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Recent Start date Enrollment

Astrocytoma × binimetinib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1 CNS 1

Conditions

Melanoma 39 Carcinoma, Non-Small-Cell Lung 15 Lung Neoplasms 10 Colorectal Neoplasms 10 Neoplasm Metastasis 9 Neoplasms 8 Brain Neoplasms 8 Pancreatic Neoplasms 6 Triple Negative Breast Neoplasms 5 Skin Neoplasms 5 Uveal Melanoma 3 Ovarian Neoplasms 3 Gastrointestinal Stromal Tumors 3 Biliary Tract Neoplasms 3 Thyroid Neoplasms 2 Skin Diseases 2 Recurrence 2 Rectal Neoplasms 2 Neurofibromatosis 1 2 Multiple Myeloma 2 Leukemia, Hairy Cell 2 Hereditary Sensory and Autonomic Neuropathies 2 Hematologic Neoplasms 2 Glioma 2 Fallopian Tube Neoplasms 2 Colonic Neoplasms 2 Breast Neoplasms 2 Spinocerebellar Degenerations 1 Solid Tumors Harboring a BRAF V600 Mutation 1 Solid Tumors 1

Interventions

Temozolomide 107 Radiotherapy 59 Carboplatin 28 Bevacizumab 28 Carmustine 26 Magnetic Resonance Spectroscopy 24 Filgrastim 20 Surgical Procedures, Operative 18 Irinotecan 18 Radiation 16 Lomustine 16 Vincristine 14 Etoposide 13 Specimen Handling 11 Radiotherapy, Intensity-Modulated 11 Procarbazine 11 Peripheral Blood Stem Cell Transplantation 11 O(6)-benzylguanine 11 Erlotinib Hydrochloride 11 Cyclophosphamide 11 sargramostim 10 Chemotherapy, Adjuvant 10 Cisplatin 9 antineoplaston AS 2-1 8 antineoplaston A10 8 Thiotepa 8 Granulocyte Colony-Stimulating Factor 8 Flucytosine 8 Everolimus 7 vocimagene amiretrorepvec 6

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT03973918 2024-10-31

BRAF

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 2 Terminated

5 enrolled 15 charts

Astrocytoma, Glioblastoma, Glioma, Gliosarcoma

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