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1 trials

Recent Start date Enrollment

Phase 2 × Astrocytoma × binimetinib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1 CNS 1

Conditions

Melanoma 18 Brain Neoplasms 6 Neoplasms 5 Carcinoma, Non-Small-Cell Lung 5 Pancreatic Neoplasms 3 Neoplasm Metastasis 3 Lung Neoplasms 3 Colorectal Neoplasms 3 Ovarian Neoplasms 2 Multiple Myeloma 2 Leukemia, Hairy Cell 2 Hematologic Neoplasms 2 Uveal Melanoma 1 Triple Negative Breast Neoplasms 1 Thyroid Neoplasms 1 Skin Neoplasms 1 Recurrence 1 Peripheral Nervous System Neoplasms 1 Noonan Syndrome 5 1 Neurofibromatosis 1 1 Neurofibromatoses 1 Neurofibroma, Plexiform 1 Neurofibroma 1 Lymphoma 1 Lymphatic Metastasis 1 Leukemia, Myeloid, Acute 1 Hereditary Sensory and Autonomic Neuropathies 1 Gliosarcoma 1 Glioma 1 Glioblastoma 1

Interventions

Temozolomide 35 Radiotherapy 17 Bevacizumab 13 Magnetic Resonance Spectroscopy 9 Carmustine 9 Carboplatin 9 antineoplaston AS 2-1 8 antineoplaston A10 8 Irinotecan 7 Cyclophosphamide 6 Filgrastim 5 Cisplatin 5 sargramostim 4 Vincristine 4 Surgical Procedures, Operative 4 Specimen Handling 4 Everolimus 4 Etoposide 4 trametinib 3 Thalidomide 3 Sunitinib 3 Radiation 3 Procarbazine 3 Peripheral Blood Stem Cell Transplantation 3 Lomustine 3 FANG vaccine 3 Chemotherapy, Adjuvant 3 talampanel 2 palbociclib 2 dabrafenib 2

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT03973918 2024-10-31

BRAF

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 2 Terminated

5 enrolled 15 charts

Astrocytoma, Glioblastoma, Glioma, Gliosarcoma

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