Clinical Trials

309 enrolled

Brain Neoplasms, Communication, Glioblastoma

NCT04189172 2026-03-18

MiDura

328 enrolled

Arnold-Chiari Malformation, Brain Neoplasms, Hydrocephalus, Meningioma, Spinal Cord Injuries, Vascular Malformations

NCT04817254 2026-03-18

Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

47 enrolled

CNSSarcoma

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT02429570 2026-03-17

Meclofenamate in Subjects With Recurrent or Progressive Brain Metastasis From Solid Tumor Primary

30 enrolled

Brain Neoplasms

NCT02971501 2026-03-17

Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain Metastases

7 enrolled 9 charts

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06946680 2026-03-13

IMPACT

18 enrolled

Brain Neoplasms, Glioblastoma, Glioma

NCT05865990 2026-03-12

TUXEDO-3

63 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms, Meningeal Neoplasms

NCT06048718 2026-03-10

TUXEDO-4

28 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT01592968 2026-03-09

Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain Metastases

88 enrolled

Brain Neoplasms, Neoplasm Metastasis

NCT02389309 2026-03-09

Dasatinib, Temsirolimus, and Cyclophosphamide in Treating Patients With Advanced, Recurrent, or Refractory Solid Tumors

14 enrolled

Brain Neoplasms

NCT04573140 2026-03-09

PNOC020

28 enrolled

CNSLymphoid

Brain Neoplasms, Glioblastoma, Glioma, Lymphoma, Follicular

NCT05353530 2026-03-09

IMPACT

39 enrolled

Brain Neoplasms, Glioblastoma

NCT05660408 2026-03-09

RNA PRIME

36 enrolled

Brain Neoplasms, Glioma

NCT06254326 2026-03-09

ADAGiO

12 enrolled

Brain Neoplasms, Oligodendroglioma

NCT06389591 2026-03-09

RNA-Lipid Particle (RNA-LP) Vaccines for Recurrent Adult Glioblastoma (GBM)

24 enrolled

Brain Neoplasms, Glioblastoma

NCT02568267 2026-03-06

STARTRK-2

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidNETSarcomaThoracic

534 enrolled 1 FDA

Thyroid Cancer, Papillary, Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Head and Neck Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Colorectal Neoplasms, Lymphoma, Large-Cell, Anaplastic, Cholangiocarcinoma, Neuroendocrine Tumors

NCT03606421 2026-03-06

CBF and NCF Changes With Brain Radiation

110 enrolled

Brain Neoplasms, Cognition Disorders

NCT01644591 2026-03-05

Stereotactic Radiosurgery in Treating Patients With Greater Than 3 Melanoma Brain Metastases

49 enrolled

CNSDermatologic

Brain Neoplasms, Melanoma

NCT04244019 2026-03-05

FLT-PET / MRI Brain Mets

30 enrolled

Brain Neoplasms

NCT04516070 2026-03-05

Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain Metastasis

55 enrolled

CNSThoracic

Brain Neoplasms, Lung Neoplasms, Small Cell Lung Carcinoma

NCT03152318 2026-03-04

rQNestin

62 enrolled

Astrocytoma, Brain Neoplasms, Disease, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Ganglioglioma

NCT07448493 2026-03-04

GASTROBRAIN

230 enrolled

CNSGastrointestinal

Brain Neoplasms, Esophageal Neoplasms, Stomach Neoplasms

NCT07448662 2026-03-04

COLBRAIN

700 enrolled

CNSGastrointestinal

Brain Neoplasms, Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT02574728 2026-03-02

AflacST1502

46 enrolled

CNSMyeloidSarcoma

Brain Neoplasms, Carcinoma, Ependymoma, Histiocytosis, Langerhans-Cell, Medulloblastoma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Neuroblastoma, Pinealoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Rhabdoid Tumor

NCT03244995 2026-03-02

Mind-Body Intervention in Glioma Couples

74 enrolled

Brain Neoplasms, Glioblastoma, Glioma

NCT05413304 2026-02-27

Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral Microdialysis

1 enrolled

Brain Neoplasms, Glioma

NCT05593094 2026-02-25

A Phase 1 Trial of ZN-A-1041 Enteric Capsules or Combination in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Solid Tumors

210 enrolled

Brain Neoplasms

NCT05288439 2026-02-23

A Study of How Proton Beam Radiotherapy (PBRT) Affects Brain Function and Quality of Life in Children and Young Adults Undergoing Treatment for a Brain Tumor

30 enrolled

Brain Neoplasms

NCT00950001 2026-02-20

Stereotactic Radiosurgery Compared to Observation in Treating Patients With Brain Metastases

132 enrolled

Brain Neoplasms

NCT07238322 2026-02-20

[18F]FET PET for Characterization of Progressive or Recurrent Glioma From Treatment Related Changes

400 enrolled

Brain Neoplasms, Glioma

NCT02645487 2026-02-17

SRS

135 enrolled

Brain Neoplasms

NCT04739761 2026-02-11

DESTINY-B12

506 enrolled 27 charts

BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT04478279 2026-02-09

A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors

BreastCNSDermatologicGenitourinary

125 enrolled

Brain Neoplasms, Breast Neoplasms, Glioblastoma, Melanoma, Prostatic Neoplasms

NCT06916715 2026-02-09

MR Elastography in Intracranial Lesions: Feasibility & Accuracy

512 enrolled

Brain Neoplasms

NCT01535911 2026-02-05

Ketones

16 enrolled

Brain Neoplasms, Glioblastoma

NCT02256137 2026-02-05

A Longitudinal Assessment of Frailty in Young Adult Survivors of Childhood Cancer

CNSLymphoidOther hematologic neoplasm

1,564 enrolled

Brain Neoplasms, Hodgkin Disease, Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04459273 2026-02-05

FAPI PET RDRC

CNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckNETOther hematologic neoplasm

26 enrolled

Adrenal Gland Neoplasms, Urinary Bladder Neoplasms, Brain Neoplasms, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Neoplasms, Unknown Primary, Skin Neoplasms, Testicular Neoplasms, Thymus Neoplasms, Thyroid Neoplasms, Cholangiocarcinoma, Neuroendocrine Tumors, Hematologic Neoplasms

NCT07389642 2026-02-05

OligoLung

46 enrolled

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT04114981 2026-01-26

Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease

242 enrolled

Brain Neoplasms

NCT04062305 2026-01-14

nTMS in Planning Stereotactic Radiosurgery in Patients With Brain Metastases in the Motor Cortex

22 enrolled

Brain Neoplasms

NCT05438212 2026-01-14

Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases

237 enrolled

Brain Neoplasms

NCT05023434 2026-01-12

A Study to Measure the Effect of Brain Stimulation on Hand Strength and Function in Patients With Brain Tumors

60 enrolled

Brain Neoplasms

NCT03277638 2026-01-08

Laser Interstitial Thermotherapy (LITT) Combined With Checkpoint Inhibitor for Recurrent GBM (RGBM)

32 enrolled

Brain Neoplasms, Glioblastoma

NCT04049669 2026-01-08

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG

130 enrolled

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioblastoma, Medulloblastoma

NCT03465618 2026-01-07

A First in Human Study Using 89Zr-cRGDY Ultrasmall Silica Particle Tracers for Malignant Brain Tumors

17 enrolled

CNSEndocrine

Brain Neoplasms, Pituitary Neoplasms

NCT02650401 2025-12-24

STARTRK-NG

CNSEndocrineGenitourinaryHead & NeckSarcoma

69 enrolled 1 FDA

Thyroid Cancer, Papillary, Brain Neoplasms, Glioma, Medulloblastoma, Neoplasm Metastasis, Wilms Tumor, Neuroblastoma, Recurrence, Salivary Gland Neoplasms, Sarcoma, Sarcoma, Ewing, Central Nervous System Neoplasms, Nephroma, Mesoblastic

NCT05503251 2025-12-24

Neuropsychological Care for Maintaining Quality of Life After Radiation Therapy in Patients With Brain Metastases

110 enrolled

Brain Neoplasms, Neoplasm Metastasis

NCT05305365 2025-12-23

Study Assessing QBS72S For Treating Brain Metastases