Clinical Trials

Brain Neoplasms

NCT06888817 2026-02-25

BRAINS

Phase 3 Recruiting

408 enrolled

Brain Neoplasms, Glioma, Radiation Injuries

NCT02669173 2026-02-23

Capecitabine + Bevacizumab in Patients With Recurrent Glioblastoma

Phase 1 Completed

12 enrolled

Phase 2 Active not recruiting

Brain Neoplasms, Glioblastoma, Recurrence

NCT03175432 2025-11-03

Bevacizumab and Atezolizumab With or Without Cobimetinib in Treating Patients With Untreated Melanoma Brain Metastases

29 enrolled

CNSDermatologic

Brain Neoplasms, Melanoma

NCT01951482 2025-08-17

Pemetrexed/Platinum With or Without Bevacizumab in Brain Metastases From Patients With EGFR/ALK Negative Non-Squamous Non-small Cell Lung Cancer

Phase 3 Completed

160 enrolled

Phase EARLY_PHASE1 Terminated

Brain Neoplasms

NCT04074785 2025-08-17

SCCC-06319

10 enrolled

Brain Neoplasms, Glioblastoma

NCT06471465 2025-08-17

BRADI

Phase 3 Recruiting

84 enrolled

Brain Neoplasms

NCT02681549 2025-08-07

Pembrolizumab Plus Bevacizumab for Treatment of Brain Metastases in Metastatic Melanoma or Non-small Cell Lung Cancer (NSCLC)

41 enrolled 20 charts

CNSDermatologicThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT03698162 2025-08-05

Precise DCE-MRI in Diagnosing Participants With Recurrent High Grade Glioma or Melanoma Brain Metastases

Phase NA Terminated

15 enrolled

CNSDermatologic

Brain Neoplasms, Melanoma

NCT03890952 2025-07-24

Translational Study of Nivolumab in Combination With Bevacizumab for Recurrent Glioblastoma

40 enrolled

Brain Neoplasms

NCT06401824 2025-05-06

Sacituzumab Govitecan and Bevacizumab for NSCLC Brain Metastases

Phase 2 Recruiting

25 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT01083966 2025-04-09

Super-Selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Vestibular Schwannoma

Phase 1 Suspended

30 enrolled

Brain Neoplasms, Neurilemmoma, Neuroma, Neuroma, Acoustic

NCT01894061 2025-02-17

NovoTTF-100A With Bevacizumab (Avastin) in Patients With Recurrent Glioblastoma

25 enrolled 16 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT01814813 2025-01-24

Vaccine Therapy With Bevacizumab Versus Bevacizumab Alone in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery

90 enrolled 13 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT06728865 2024-12-11

Better Brain

Phase 2 Recruiting

70 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Meningeal Carcinomatosis

NCT05807893 2024-11-13

SUPER BRAIN

Phase 2/3 Completed

40 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT05271240 2024-09-19

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

Phase 3 Recruiting

432 enrolled

Brain Neoplasms, Glioblastoma, Glioma

NCT01811498 2024-01-30

Repeated Super-Selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Newly Diagnosed GBM

Phase 1/2 Completed

31 enrolled 7 charts

Phase 2 Not yet recruiting

Brain Neoplasms, Glioblastoma

NCT06210438 2024-01-18

SHR-A1921 Combined With Bevacizumab in Triple-negative Breast Cancer With Brain Metastases

24 enrolled

Brain Neoplasms

NCT04345146 2023-08-28

Bevacizumab Combined With Fractionated Stereotactic Radiotherapy for 1 to 10 Brain Metastases From NSCLC

100 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT02490878 2023-03-23

Corticosteroids + Bevacizumab vs. Corticosteroids + Placebo (BEST) for Radionecrosis After Radiosurgery for Brain Metastases

19 enrolled 15 charts

Brain Neoplasms

NCT02343549 2022-11-03

A Phase II Study of Optune (NovoTTF) in Combination With Bevacizumab (BEV) and Temozolomide (TMZ) in Patients With Newly Diagnosed Unresectable Glioblastoma (GBM)

13 enrolled 23 charts

Brain Neoplasms, Neurologic Manifestations

NCT02843230 2022-04-08

Monitoring Anti-angiogenic Therapy in Brain Tumors by Advanced MRI

Completed

30 enrolled

Brain Neoplasms, Glioblastoma

NCT02010606 2021-11-22

Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma

Phase 1 Completed

39 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms

NCT00879437 2021-07-21

Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma

38 enrolled 53 charts

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neuroepithelial, Gliosarcoma

NCT02185352 2021-05-07

A-Plus

Phase 2 Unknown

120 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT01740258 2021-01-26

BBP

68 enrolled 11 charts

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT01125046 2021-01-22

Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas

50 enrolled 13 charts

Brain Neoplasms, Ependymoma, Meningioma, Neurofibromatosis 1, Neuroma, Acoustic, Neurofibromatosis 2

NCT00924820 2020-12-31

A Pilot Study of Bevacizumab for Neoplastic Meningitis

Phase 1/2 Completed

20 enrolled 7 charts

Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Meningeal Carcinomatosis

NCT00883688 2020-08-26

Bevacizumab and Lapatinib in Children With Recurrent or Refractory Ependymoma

24 enrolled 5 charts

Brain Neoplasms, Ependymoma, Neuroectodermal Tumors, Primitive, Glioma, Subependymal

NCT00795665 2020-05-12

Bevacizumab and Carmustine in Treating Patients With Relapsed or Progressive High-Grade Glioma

7 enrolled 4 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT01067469 2020-03-17

Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM)

83 enrolled 15 charts

Brain Neoplasms, Glioblastoma

NCT00337207 2020-02-07

Bevacizumab in Treating Patients With Recurrent or Progressive Glioma

55 enrolled 10 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01392209 2019-11-22

Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant Glioma

Phase 1 Completed

15 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT00892177 2019-10-21

Dasatinib and Bevacizumab in Treating Patients With Recurrent or Progressive High-Grade Glioma or Glioblastoma Multiforme

144 enrolled 14 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT01582152 2019-06-05

Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma

Phase 1/2 Terminated

12 enrolled 7 charts

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT02120287 2019-05-07

Border Zone Stereotactic Radiosurgery With Bevacizumab in Patients With Glioblastoma Multiforme

16 enrolled 20 charts

Phase EARLY_PHASE1 Completed

Brain Neoplasms, Glioblastoma

NCT02768389 2019-03-15

Feasibility Trial of the Modified Atkins Diet and Bevacizumab for Recurrent Glioblastoma

18 enrolled

Brain Neoplasms, Glioblastoma

NCT02655536 2018-07-10

BRILLIANT

Phase 2 Unknown

109 enrolled

Phase EARLY_PHASE1 Terminated

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT01086345 2018-07-03

Radiosurgery Plus Bevacizumab in Glioblastoma

9 enrolled

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT00621686 2018-05-08

Bevacizumab and Sorafenib in Treating Patients With Recurrent Glioblastoma Multiforme

54 enrolled 8 charts

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00782756 2018-02-06

Bevacizumab, Temozolomide and Hypofractionated Radiotherapy for Patients With Newly Diagnosed Malignant Glioma

40 enrolled 10 charts

Brain Neoplasms, Glioblastoma, Glioma

NCT02672995 2017-08-18

Fractionated Stereotactic Radiosurgery With Concurrent Bevacizumab for Brain Metastases: A Phase I Dose-escalation Trial

Phase 1 Unknown

36 enrolled

Brain Neoplasms

NCT01526837 2017-07-12

Bevacizumab (Avastin) Into the Tumor Resection Cavity in Subjects With Glioblastoma Multiforme at First Recurrence

Phase 1 Terminated

1 enrolled

Brain Neoplasms, Glioblastoma

NCT00595322 2017-05-23

Bevacizumab in the Radiation Treatment of Recurrent Malignant Glioma

Phase NA Completed

25 enrolled

Brain Neoplasms, Glioma

NCT00883298 2017-03-30

Bi-weekly Temozolomide Plus Bevacizumab for Adult Patients With Recurrent Glioblastoma Multiforme

30 enrolled

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT01738646 2017-03-06

Ph II SAHA and Bevacizumab for Recurrent Malignant Glioma Patients

48 enrolled 10 charts

Brain Neoplasms, Glioblastoma, Glioma

NCT02898012 2016-09-13

ATAG

70 enrolled

Brain Neoplasms, Glioblastoma

NCT01105702 2016-08-04

Temodar (Temozolomide), Bevacizumab, Lithium and Radiation for High Grade Glioma

28 enrolled 9 charts