Clinical Trials Browser

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT01622868 2023-10-17

Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer

Phase 2 Completed

143 enrolled 24 charts

BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT00883688 2020-08-26

Bevacizumab and Lapatinib in Children With Recurrent or Refractory Ependymoma

Phase 2 Completed

24 enrolled 5 charts

CNS

Brain Neoplasms, Ependymoma, Neuroectodermal Tumors, Primitive, Glioma, Subependymal

NCT00263588 2019-12-12

Lapatinib for Brain Metastases In ErbB2-Positive Breast Cancer

Phase 2 Completed

242 enrolled 19 charts

BreastCNS

Brain Neoplasms, Breast Neoplasms, Neoplasms

NCT00820222 2019-04-02

Lapatinib Plus Capecitabine Versus Trastuzumab Plus Capecitabine in ErbB2 (HER2) Positive Metastatic Breast Cancer

Phase 3 Completed

540 enrolled 18 charts

BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT00826241 2019-03-22

Dose-Dense Temozolomide + Lapatinib for Recurrent Ependymoma

Phase 2 Completed

58 enrolled 11 charts

CNS

Brain Neoplasms, Ependymoma, Spinal Cord Neoplasms

NCT00107003 2018-07-05

GW572016 to Treat Recurrent Malignant Brain Tumors

Phase 2 Completed

9 enrolled

CNSSarcoma

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Gliosarcoma

NCT00437073 2015-10-15

Brain Metastases In ErbB2-Positive Breast Cancer

Phase 2 Terminated

22 enrolled 8 charts

BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT01218529 2014-12-31

Lapatinib and WBRT for Patients With Brain Metastases From Lung or Breast Tumors

Phase 2 Completed

82 enrolled

BreastCNSThoracic

Brain Neoplasms, Breast Neoplasms, Lung Neoplasms

NCT00099060 2014-01-27

Lapatinib in Treating Patients With Recurrent Glioblastoma Multiforme

Phase 1/2 Completed

24 enrolled

CNSSarcoma

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00098605 2013-06-06

Lapatinib in Treating Brain Metastases in Patients With Stage IV Breast Cancer and Brain Metastases

Phase 2 Completed

37 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms, Breast Neoplasms, Male

NCT00967031 2013-01-18

Lapatinib Ditosylate and Capecitabine in Treating Patients With Stage IV Breast Cancer and Brain Metastases

Phase 2 Completed

45 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis, Breast Neoplasms, Male

NCT00614978 2012-09-19

LAPTEM

Phase 1 Completed

18 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms

Clinical Trials

Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma

Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer

Bevacizumab and Lapatinib in Children With Recurrent or Refractory Ependymoma

Lapatinib for Brain Metastases In ErbB2-Positive Breast Cancer

Lapatinib Plus Capecitabine Versus Trastuzumab Plus Capecitabine in ErbB2 (HER2) Positive Metastatic Breast Cancer

Dose-Dense Temozolomide + Lapatinib for Recurrent Ependymoma

GW572016 to Treat Recurrent Malignant Brain Tumors

Brain Metastases In ErbB2-Positive Breast Cancer

Lapatinib and WBRT for Patients With Brain Metastases From Lung or Breast Tumors

Lapatinib in Treating Patients With Recurrent Glioblastoma Multiforme

Lapatinib in Treating Brain Metastases in Patients With Stage IV Breast Cancer and Brain Metastases

Lapatinib Ditosylate and Capecitabine in Treating Patients With Stage IV Breast Cancer and Brain Metastases

LAPTEM