Clinical Trials

21 enrolled 12 charts

Phase 1 Active not recruiting

Brain Neoplasms, Glioblastoma

NCT04460937 2025-07-08

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers

4 enrolled 9 charts

CNSGastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Brain Neoplasms, Meningeal Carcinomatosis

NCT00838929 2025-05-04

Study of the Combination of Vorinostat and Radiation Therapy for the Treatment of Patients With Brain Metastases

17 enrolled 8 charts

BreastCNSThoracic

Brain Neoplasms, Breast Neoplasms, Lung Neoplasms

NCT00639262 2025-05-02

Combination of Sorafenib and Radiation for Brain Metastases and Primary Brain Tumors

35 enrolled

Brain Neoplasms

NCT03250299 2024-06-24

Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

26 enrolled 17 charts

Brain Neoplasms, Glioblastoma

NCT06137651 2024-04-01

Trotabresib in Combination With Vinorelbine and Radiation Therapy for the Treatment of HER2+ Breast Cancer With Central Nervous System or Leptomeningeal Metastasis

Phase 1 Withdrawn

BreastCNS

Brain Neoplasms, Breast Neoplasms, Meningeal Carcinomatosis

NCT03705351 2024-03-04

Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBM

7 enrolled 12 charts

Brain Neoplasms, Glioblastoma

NCT03696355 2023-01-18

Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas

27 enrolled

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms

NCT02903069 2021-04-19

Study of Marizomib With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Brain Cancer

66 enrolled

Brain Neoplasms, Glioblastoma, Glioma

NCT00734526 2018-11-09

Phase I Portion of Phase I/II Sorafenib With Radiation and Temozolomide in Newly Diagnosed Glioblastoma or Gliosarcoma

18 enrolled

CNSSarcoma

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT02149459 2017-10-27

SMC 0712-13

Phase 1 Unknown

18 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Insulin Resistance, Ketosis

NCT00946673 2017-10-06

Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer

17 enrolled

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00328575 2016-10-21

Using Intensity Modulated Radiation Therapy (IMRT) for Brain Metastases

10 enrolled

Brain Neoplasms, Neoplasm Metastasis, Neoplasms

NCT00003625 2014-07-28

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Brain Stem Glioma

7 enrolled

Brain Neoplasms, Central Nervous System Neoplasms

NCT00003935 2014-07-28

Combination Chemotherapy Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma

31 enrolled

Brain Neoplasms, Central Nervous System Neoplasms

NCT00650923 2014-05-30

Aflibercept, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme, Gliosarcoma, or Other Malignant Glioma

61 enrolled

CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT00469937 2012-02-28

Ph I Study of Lithium During Whole Brain Radiotherapy For Patients With Brain Metastases

9 enrolled

Brain Neoplasms, Radiation Injuries, Central Nervous System Neoplasms, Neurotoxicity Syndromes

NCT00089427 2011-07-04

IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma

24 enrolled