Announcements Trials

Browse Landscape Eligibility

Clinical Trials

1 trials

Recent Start date Enrollment

Phase 1/2 × Brain Neoplasms × defactinib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Dermatologic 1 CNS 1

Conditions

Pancreatic Neoplasms 2 Ovarian Neoplasms 1 Neoplasms 1 Neoplasm Metastasis 1 Mesothelioma 1 Melanoma 1 Glioblastoma 1 Carcinoma, Non-Small-Cell Lung 1 Brain Neoplasms 1

Interventions

Temozolomide 23 Radiosurgery 12 Bevacizumab 11 Carboplatin 8 pembrolizumab 7 Radiotherapy 7 Trastuzumab 6 Erlotinib Hydrochloride 5 abemaciclib 4 Paclitaxel 4 Capecitabine 4 tipifarnib 3 temsirolimus 3 Sirolimus 3 Radiation 3 Irinotecan 3 Ipilimumab 3 Everolimus 3 Aminolevulinic Acid 3 tucatinib 2 pertuzumab 2 durvalumab 2 alovudine 2 Vorinostat 2 Surgical Procedures, Operative 2 Sorafenib 2 Nivolumab 2 NVP-BKM120 2 Mental Status and Dementia Tests 2 Interleukin-2 2

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT06194929 2025-12-03

DETERMINE

University of Utah

Phase 1/2 Recruiting

CNSDermatologic

Brain Neoplasms, Melanoma

Data powered by HemOnc (CC BY 4.0) Colophon ⚡