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Recent Start date Enrollment

OTHER × Brain Neoplasms × defactinib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Dermatologic 1 CNS 1

Conditions

Pancreatic Neoplasms 6 Glioblastoma 2 Uveal Melanoma 1 Uterine Cervical Neoplasms 1 Thyroid Neoplasms 1 Stomach Neoplasms 1 Phase IB 1 Ovarian Neoplasms 1 Neoplasms 1 Mesothelioma, Malignant 1 Mesothelioma 1 Melanoma 1 Lung Neoplasms 1 Low-Grade Serous Ovarian Cancer 1 Carcinoma, Non-Small-Cell Lung 1 Carcinoma, Endometrioid 1 Brain Neoplasms 1 Advanced Colorectal Cancer 1 Adenocarcinoma of Lung 1

Interventions

Radiosurgery 104 Temozolomide 94 Bevacizumab 64 Magnetic Resonance Spectroscopy 62 Radiotherapy 60 Carboplatin 29 pembrolizumab 26 Irinotecan 24 Surgical Procedures, Operative 22 Nivolumab 22 Etoposide 20 Radiation 19 Magnetic Resonance Imaging 19 Ipilimumab 19 Erlotinib Hydrochloride 19 Cyclophosphamide 19 Surveys and Questionnaires 18 Aminolevulinic Acid 18 Specimen Handling 15 Pemetrexed 15 Mental Status and Dementia Tests 14 Cisplatin 14 Topotecan 13 Carmustine 13 Neuropsychological Tests 12 Drug Therapy 11 Trastuzumab 10 Saline Solution 10 Imatinib Mesylate 10 Gefitinib 10

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT06194929 2025-12-03

DETERMINE

University of Utah

Phase 1/2 Recruiting

CNSDermatologic

Brain Neoplasms, Melanoma

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