A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
Phase 1 Recruiting
124 enrolled
A Phase 1/1b Study of IAM1363 in HER2 Cancers
Phase 1 Recruiting
243 enrolled
Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies
Phase 1 Recruiting
90 enrolled
A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer
Phase 1 Recruiting
180 enrolled
A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement
Phase 1 Terminated
65 enrolled 52 charts
A First-In-Human, Phase 1 Study Evaluating Oral TACC3 PPI Inhibitor, AO-252, in Advanced Solid Tumors With or Without Brain Metastases
Phase 1 Recruiting
86 enrolled
Trial of ZN-A-1041 Enteric Capsules in Patients With HER2-Positive Advanced Solid Tumors
Phase 1 Completed
61 enrolled
Study to Evaluate 5-ALA Combined With CV01 Delivery of Ultrasound in Recurrent High Grade Glioma
Phase 1 Completed
22 enrolled
CerebralEDV
Phase 1 Completed
9 enrolled
Safety & Efficacy/Tolerability of Rhenium-186 NanoLiposomes (186RNL) for Patients Who Received a Prior 186RNL Treatment
Phase 1 Recruiting
40 enrolled
BP31510 (Ubidecarenone,USP) Nanosuspension for Intravenous Injection to Patients With Solid Tumors
Phase 1 Completed
97 enrolled
(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations
Phase 1 Terminated
103 enrolled
KONQUER
Phase 1 Terminated
10 enrolled
Safety and Effectiveness of ABM-168 in Adults with Advanced Solid Tumors.
Phase 1 Terminated
12 enrolled
PIRATE
Phase 1 Terminated
2 enrolled
Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma
Phase 1 Terminated
26 enrolled 17 charts
Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors
Phase 1 Terminated
29 enrolled
Study of BLZ-100 in Pediatric Subjects With CNS Tumors
Phase 1 Completed
29 enrolled
Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S
Phase 1 Completed
15 enrolled
BRAINSTORM
Phase 1 Completed
29 enrolled
Monteris AutoLITT™ FIM Safety Trial for Recurrent/Progressive Brain Tumors
Phase 1 Completed
10 enrolled
KOURAGE
Phase 1 Terminated
9 enrolled
Study of Marizomib With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Brain Cancer
Phase 1 Completed
66 enrolled
BLOOM
Phase 1 Completed
108 enrolled
Dose Escalation Study to Determine the Safety of IFN-Beta Gene Transfer in the Treatment of Grade III & Grade IV Gliomas
Phase 1 Completed
12 enrolled
DM-CHOC-PEN
Phase 1 Completed
23 enrolled
Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors
Phase 1 Completed
81 enrolled
Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies
Phase 1 Completed
89 enrolled
A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511
Phase 1 Terminated
65 enrolled
To Evaluate the Safety, Activity and Pharmacokinetics of Marqibo in Children and Adolescents With Refractory Cancer
Phase 1 Completed
22 enrolled
Study of Insulin-like Growth Factor (IGF)-Methotrexate Conjugate in the Treatment of Advanced Tumors Expressing IGF-1R
Phase 1 Completed
92 enrolled
Dendritic Cell Therapy for Brain Metastases From Breast- or Lung Cancer
Phase 1 Unknown
24 enrolled
DNX-2401 (Formerly Known as Delta-24-RGD-4C) for Recurrent Malignant Gliomas
Phase 1 Completed
37 enrolled
A Study of a Retroviral Replicating Vector Combined With a Prodrug Administered to Patients With Recurrent Malignant Glioma
Phase 1 Completed
54 enrolled
Study of a Retroviral Replicating Vector Combined With a Prodrug to Treat Patients Undergoing Surgery for a Recurrent Malignant Brain Tumor
Phase 1 Completed
58 enrolled
Study of a Retroviral Replicating Vector Given Intravenously to Patients Undergoing Surgery for Recurrent Brain Tumor
Phase 1 Completed
17 enrolled
A Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain Metastases
Phase 1 Completed
80 enrolled
PET Imaging of Intracranial Cancers With 18F-FSPG
Phase 1 Terminated
26 enrolled
ALECSAT-GBM
Phase 1 Completed
23 enrolled
AMG 595 First-in-Human in Recurrent Gliomas
Phase 1 Completed
32 enrolled
A Phase 1, Open-Label, Dose Escalation Study of ANG1005 in Patients With Advanced Solid Tumors and Metastatic Brain Cancer
Phase 1 Completed
56 enrolled
Study to Demonstrate the Safety of WBR Administered at the Same Time as Intrathecal Liposomal Cytarabine (DepoCyte®) Versus Intrathecal Liposomal Cytarabine (DepoCyte®) Administered After WBR for the Treatment of Solid Tumour Neoplastic Meningitis in Patients With or Without Brain Metastasis.
Phase 1 Completed
18 enrolled
A Phase I Trial of Enzastaurin (LY317615) in Combination With Carboplatin in Adults With Recurrent Gliomas
Phase 1 Completed
58 enrolled
Yttrium Y 90 SMT 487 in Treating Patients With Refractory or Recurrent Cancer
Phase 1 Completed
60 enrolled
Safety & Radiation Distribution Study of Cotara® in Patients With Recurrent Glioblastoma Multiforme
Phase 1 Completed
12 enrolled
IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma
Phase 1 Completed
24 enrolled
Trans Sodium Crocetinate (TSC) Study of Intra-tumoral Oxygen Concentration, Safety, and Pharmacokinetics in Patients With High Grade Glioma
Phase 1 Terminated
1 enrolled
Phase I : Cediranib in Combination With Lomustine Chemotherapy in Recurrent Malignant Brain Tumour
Phase 1 Completed
20 enrolled
In Vivo Confocal Microscopy Tumor Atlas Study
Phase 1 Unknown
150 enrolled
In Vivo Confocal Endomicroscopy of the Brain
Phase 1 Completed
30 enrolled