Clinical Trials Browser

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT02360215 2025-04-23

Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients With Brain Metastases

Phase 3 Completed

518 enrolled 40 charts

CNS

Brain Neoplasms, Cognitive Dysfunction

NCT03632135 2025-04-15

CSCRGBM

Phase 3 Completed

78 enrolled 10 charts

CNS

Brain Neoplasms, Glioblastoma

NCT06496971 2024-11-14

A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients

Phase 3 Recruiting

32 enrolled

CNS

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neoplasms, Nerve Tissue

NCT05897658 2024-10-23

LeviTaTe Pilot

Phase 3 Not yet recruiting

70 enrolled

CNS

Brain Neoplasms, Seizures

NCT05271240 2024-09-19

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

Phase 3 Recruiting

432 enrolled

CNS

Brain Neoplasms, Glioblastoma, Glioma

NCT04395339 2024-08-01

GLORY

Phase 3 Terminated

51 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms, Gangliosidoses, Radiation Injuries, Gangliosidosis, GM1, Cognitive Dysfunction

NCT06477939 2024-06-27

THREE-GLEES

Phase 3 Not yet recruiting

554 enrolled

CNS

Hypoxia, Brain Neoplasms, Glioblastoma

NCT06229483 2024-04-04

The Effects of Intraoperative Tranexamic Acid on Perioperative Bleeding In Craniotomies

Phase 3 Recruiting

102 enrolled

CNS

Brain Neoplasms, Hemorrhage

NCT03149003 2023-11-15

A Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapy

Phase 3 Completed

221 enrolled 17 charts

CNSGenitourinary

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Wilms Tumor

NCT05144867 2023-10-17

SRSvsWBRT

Phase 3 Unknown

98 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT00548756 2023-06-07

Randomized Trial Comparing Radiosurgery With vs Without Whole Brain Radiotherapy

Phase 3 Completed

152 enrolled

CNS

Brain Neoplasms

NCT02573324 2023-05-11

Intellance1

Phase 3 Completed

691 enrolled 28 charts

CNSSarcoma

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT03613181 2023-04-24

ANGLeD

Phase 3 Unknown

150 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms, Meningeal Neoplasms, Meningeal Carcinomatosis

NCT05049707 2023-04-12

Does Perioperative Intravenous Magnesium Affect Postoperative Quality of Recovery in Craniotomy Surgery Patients?

Phase 3 Unknown

110 enrolled

CNS

Brain Neoplasms

NCT02617589 2023-03-28

CheckMate 498

Phase 3 Completed

560 enrolled 14 charts

CNS

Brain Neoplasms

Clinical Trials

IPAX BrIGHT

Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain Metastases

BRAINS

Stereotactic Radiosurgery Compared to Observation in Treating Patients With Brain Metastases

LIBRA

DESTINY-B12

18F-DOPA II - PET Imaging Optimization

18F-FLUC PET/MR in Patients With Brain Mets

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

GDX-44-016

BrainUS-AI

Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease

Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

RENESANS

Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors

EMBRAIN

LIMITLESS

Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile-ROADS (Radiation One and Done Study)

Study Comparing Investigational Drug HBI-8000 + Nivolumab vs. Placebo + Nivolumab in Patients With Advanced Melanoma

SISMIC

ECOG-Anaes

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases

STAR-3

REVELATE

Pemetrexed/Platinum With or Without Bevacizumab in Brain Metastases From Patients With EGFR/ALK Negative Non-Squamous Non-small Cell Lung Cancer

BRADI

Pre- Versus Post-operative SRS for Resectable Brain Metastases

SHARP

CheckMate548

Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients With Brain Metastases

CSCRGBM

A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients

LeviTaTe Pilot

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

GLORY

THREE-GLEES

The Effects of Intraoperative Tranexamic Acid on Perioperative Bleeding In Craniotomies

A Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapy

SRSvsWBRT

Randomized Trial Comparing Radiosurgery With vs Without Whole Brain Radiotherapy

Intellance1

ANGLeD

Does Perioperative Intravenous Magnesium Affect Postoperative Quality of Recovery in Craniotomy Surgery Patients?

CheckMate 498