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NCT01068782 2026-02-25

Multiple Doses and Regimens of Cabozantinib in Subjects With Grade IV Astrocytic Tumors in First or Second Relapse

Phase 2 Terminated

19 enrolled 10 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT06098248 2025-12-15

cCeLLExvivo

Phase NA Terminated

285 enrolled 5 charts

Brain Neoplasms

NCT04543188 2025-10-23

A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement

Phase 1 Terminated

65 enrolled 52 charts

CNSDermatologicThoracic

Brain Diseases, Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasms, Central Nervous System Neoplasms

NCT04712721 2025-10-10

Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins.

Phase EARLY_PHASE1 Terminated

Brain Neoplasms, Breast Neoplasms, Glioblastoma

NCT03149575 2025-09-04

STAR-3

Phase 3 Terminated

Brain Neoplasms, Glioblastoma, Glioma

NCT06038760 2025-07-30

PEAR-GLIO

Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Neoplasms, Oligodendroglioma

NCT00538343 2025-05-29

RTA 744 in Breast Cancer Patients With Progression of Previously Irradiated Brain Metastases

Phase 2 Terminated

Brain Neoplasms, Breast Neoplasms

NCT05241873 2025-02-10

(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations

Phase 1 Terminated

Adenocarcinoma, Brain Neoplasms, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT03717142 2025-01-15

Feasibility of the LUM Imaging System for Detection of Cancer to the Brain

Phase NA Terminated

Brain Neoplasms, Glioblastoma

NCT04771897 2024-12-20

KONQUER

Phase 1 Terminated

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Glioma

NCT05831995 2024-12-06

Safety and Effectiveness of ABM-168 in Adults with Advanced Solid Tumors.

Phase 1 Terminated

CNSDermatologicGastrointestinalThoracic

Brain Neoplasms, Glioblastoma, Lung Neoplasms, Melanoma, Pancreatic Neoplasms, Colorectal Neoplasms

NCT04525014 2024-10-31

PIRATE

Phase 1 Terminated

Brain Neoplasms, Neoplasms, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT03250299 2024-06-24

Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Phase 1 Terminated

26 enrolled 17 charts

Brain Neoplasms, Glioblastoma

NCT04901806 2024-03-28

Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors

Phase 1 Terminated

Brain Neoplasms, Desmoplastic Small Round Cell Tumor

NCT03911869 2023-05-31

POLARIS

Phase 2 Terminated

13 enrolled 55 charts

CNSDermatologic

Brain Neoplasms, Melanoma

NCT01986348 2023-01-26

KING

Phase 2 Terminated

76 enrolled 16 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT00479765 2022-06-22

A Phase 1 / 2 Dose Escalation Study of Locally-Administered OncoGel™ in Subjects With Recurrent Glioma

Phase 1/2 Terminated

4 enrolled 5 charts

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Recurrence

NCT02154529 2022-04-27

Study of the Combination of KD019 and Trastuzumab in Subjects With HER2-Positive Metastatic Breast Cancer

Phase 1/2 Terminated

17 enrolled 19 charts

Brain Neoplasms

NCT02765165 2021-07-23

Phase 1/2 Study of USL311 +/- Lomustine in Advanced Solid Tumors or Relapsed/Recurrent Glioblastoma Multiforme (GBM)

Phase 1/2 Terminated

26 enrolled 20 charts

Brain Neoplasms, Glioblastoma, Neoplasms, Recurrence

NCT03967093 2021-07-22

KOURAGE

Phase 1 Terminated

Brain Neoplasms, Ependymoma, Neoplasms

NCT04327011 2020-03-30

A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511

Phase 1 Terminated

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT01497665 2019-01-22

GRABM-L

Phase 2 Terminated

16 enrolled 7 charts

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT01978236 2018-08-17

Dabrafenib/Trametinib, BRAF or BRAF AND MEK Pre-op With BRAF and MEK Post-op, Phase IIB, Melanoma With Brain Mets,Biomarkers and Metabolites

Phase 2 Terminated

6 enrolled 9 charts

CNSDermatologic

Brain Neoplasms, Melanoma

NCT01229644 2018-07-05

Study of Crenolanib, a Selective and Potent Inhibitor of PDGFR, for the Treatment of Adult Gliomas

Phase 2 Terminated

Brain Neoplasms, Glioma

NCT01870726 2018-05-30

Safety and Efficacy of INC280 and Buparlisib (BKM120) in Patients With Recurrent Glioblastoma

Phase 1/2 Terminated

43 enrolled 22 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT00638963 2017-06-14

STOP

Phase 2 Terminated

6 enrolled 9 charts

Brain Neoplasms, Breast Neoplasms, Neoplasms, Second Primary

NCT00171938 2017-02-24

Open-label Trial of Imatinib Mesylate in Patients With Unresectable Recurrent Glioblastoma Multiforme Expressing PDGFR (Platelet Derived Growth Factor Receptors)

Phase 2 Terminated

Brain Neoplasms, Glioblastoma

NCT02370563 2016-09-02

PET Imaging of Intracranial Cancers With 18F-FSPG

Phase 1 Terminated

Brain Neoplasms

NCT01132664 2016-08-17

Phase 1b/2 Study of BKM120 Plus Trastuzumab in Patients With HER2-positive Breast Cancer

Phase 1/2 Terminated

72 enrolled 15 charts

Brain Neoplasms, Breast Neoplasms

NCT01756729 2016-03-02

Post-approval Study of NovoTTF-100A in Recurrent GBM Patients

Phase 4 Terminated

Brain Neoplasms, Glioblastoma, Recurrence

NCT00437073 2015-10-15

Brain Metastases In ErbB2-Positive Breast Cancer

Phase 2 Terminated

22 enrolled 8 charts

Brain Neoplasms, Breast Neoplasms

NCT00121420 2014-05-09

Study of Motexafin Gadolinium With Whole Brain Radiation Therapy Followed by Stereotactic Radiosurgery Boost in the Treatment of Patients With Brain Metastases

Phase 2 Terminated

BreastCNSDermatologicGenitourinaryThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis

NCT01369121 2013-07-30

Tolerability Study of Xerecept® in Pediatric Patients

Phase 1/2 Terminated

Brain Edema, Brain Neoplasms, Edema

NCT00696943 2013-02-15

18F ML-10 for Early Detection of Response of Brain Metastases to SRS

Phase 2 Terminated

Brain Neoplasms

NCT00872482 2011-07-01

A Study of Nimotuzumab in Combination With Radiation Therapy in Patients With Brain Metastases

Phase 2 Terminated

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT01018290 2011-06-08

Navigated Transcranial Magnetic Stimulation in Tumor Surgery

Brain Neoplasms

NCT00826930 2010-08-12

Trans Sodium Crocetinate (TSC) Study of Intra-tumoral Oxygen Concentration, Safety, and Pharmacokinetics in Patients With High Grade Glioma

Phase 1 Terminated

Brain Neoplasms, Glioma

NCT00730262 2009-12-30

Efficacy Study of TLN-4601 in Patients With Recurring Glioblastoma Multiforme

Phase 2 Terminated

Brain Neoplasms, Glioblastoma

NCT00234442 2009-06-30

Iressa in the Treatment of Brain Metastases From Non Small Cell Lung Cancer

Phase 2 Terminated

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT00691522 2009-01-09

Imaging Study of XERECEPT® Treatment for Peritumoral Brain Edema (PBE)

Phase 2 Terminated

Brain Neoplasms

NCT00115453 2008-08-18

Boron Neutron Capture Therapy (BNCT) as Treatment of Glioblastoma

Phase 1/2 Terminated

Brain Neoplasms, Glioblastoma