Clinical Trials

47 enrolled

CNSSarcoma

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT02429570 2026-03-17

Meclofenamate in Subjects With Recurrent or Progressive Brain Metastasis From Solid Tumor Primary

30 enrolled

Brain Neoplasms

NCT02971501 2026-03-17

Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain Metastases

7 enrolled 9 charts

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06946680 2026-03-13

IMPACT

18 enrolled

Brain Neoplasms, Glioblastoma, Glioma

NCT05865990 2026-03-12

TUXEDO-3

63 enrolled

Brain Neoplasms, Breast Neoplasms, Meningeal Neoplasms

NCT06048718 2026-03-10

TUXEDO-4

28 enrolled

Brain Neoplasms, Breast Neoplasms

NCT01592968 2026-03-09

Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain Metastases

88 enrolled

Brain Neoplasms, Neoplasm Metastasis

NCT02389309 2026-03-09

Dasatinib, Temsirolimus, and Cyclophosphamide in Treating Patients With Advanced, Recurrent, or Refractory Solid Tumors

14 enrolled

Brain Neoplasms

NCT04573140 2026-03-09

PNOC020

28 enrolled

CNSLymphoid

Brain Neoplasms, Glioblastoma, Glioma, Lymphoma, Follicular

NCT05353530 2026-03-09

IMPACT

39 enrolled

Brain Neoplasms, Glioblastoma

NCT05660408 2026-03-09

RNA PRIME

36 enrolled

Brain Neoplasms, Glioma

NCT06254326 2026-03-09

ADAGiO

12 enrolled

Brain Neoplasms, Oligodendroglioma

NCT06389591 2026-03-09

RNA-Lipid Particle (RNA-LP) Vaccines for Recurrent Adult Glioblastoma (GBM)

24 enrolled

Brain Neoplasms, Glioblastoma

NCT02568267 2026-03-06

STARTRK-2

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidNETSarcomaThoracic

534 enrolled 1 FDA

Thyroid Cancer, Papillary, Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Head and Neck Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Colorectal Neoplasms, Lymphoma, Large-Cell, Anaplastic, Cholangiocarcinoma, Neuroendocrine Tumors

NCT01644591 2026-03-05

Stereotactic Radiosurgery in Treating Patients With Greater Than 3 Melanoma Brain Metastases

49 enrolled

CNSDermatologic

Brain Neoplasms, Melanoma

NCT04516070 2026-03-05

Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain Metastasis

55 enrolled

CNSThoracic

Brain Neoplasms, Lung Neoplasms, Small Cell Lung Carcinoma

NCT03152318 2026-03-04

rQNestin

62 enrolled

Astrocytoma, Brain Neoplasms, Disease, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Ganglioglioma

NCT02574728 2026-03-02

AflacST1502

46 enrolled

CNSMyeloidSarcoma

Brain Neoplasms, Carcinoma, Ependymoma, Histiocytosis, Langerhans-Cell, Medulloblastoma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Neuroblastoma, Pinealoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Rhabdoid Tumor

NCT03244995 2026-03-02

Mind-Body Intervention in Glioma Couples

74 enrolled

Brain Neoplasms, Glioblastoma, Glioma

NCT05413304 2026-02-27

Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral Microdialysis

1 enrolled

Brain Neoplasms, Glioma

NCT05593094 2026-02-25

A Phase 1 Trial of ZN-A-1041 Enteric Capsules or Combination in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Solid Tumors

210 enrolled

Brain Neoplasms

NCT05288439 2026-02-23

A Study of How Proton Beam Radiotherapy (PBRT) Affects Brain Function and Quality of Life in Children and Young Adults Undergoing Treatment for a Brain Tumor

30 enrolled

Brain Neoplasms

NCT00950001 2026-02-20

Stereotactic Radiosurgery Compared to Observation in Treating Patients With Brain Metastases

132 enrolled

Brain Neoplasms

NCT02645487 2026-02-17

SRS

135 enrolled

Brain Neoplasms

NCT04739761 2026-02-11

DESTINY-B12

506 enrolled 27 charts

Brain Neoplasms, Breast Neoplasms

NCT04478279 2026-02-09

A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors

BreastCNSDermatologicGenitourinary

125 enrolled

Brain Neoplasms, Breast Neoplasms, Glioblastoma, Melanoma, Prostatic Neoplasms

NCT01535911 2026-02-05

Ketones

16 enrolled

Brain Neoplasms, Glioblastoma

NCT04459273 2026-02-05

FAPI PET RDRC

CNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckNETOther hematologic neoplasm

26 enrolled

Adrenal Gland Neoplasms, Urinary Bladder Neoplasms, Brain Neoplasms, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Neoplasms, Unknown Primary, Skin Neoplasms, Testicular Neoplasms, Thymus Neoplasms, Thyroid Neoplasms, Cholangiocarcinoma, Neuroendocrine Tumors, Hematologic Neoplasms

NCT04114981 2026-01-26

Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease

242 enrolled

Brain Neoplasms

NCT04062305 2026-01-14

nTMS in Planning Stereotactic Radiosurgery in Patients With Brain Metastases in the Motor Cortex

22 enrolled

Brain Neoplasms

NCT05438212 2026-01-14

Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases

237 enrolled

Brain Neoplasms

NCT03277638 2026-01-08

Laser Interstitial Thermotherapy (LITT) Combined With Checkpoint Inhibitor for Recurrent GBM (RGBM)

32 enrolled

Brain Neoplasms, Glioblastoma

NCT04049669 2026-01-08

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG

130 enrolled

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioblastoma, Medulloblastoma

NCT03465618 2026-01-07

A First in Human Study Using 89Zr-cRGDY Ultrasmall Silica Particle Tracers for Malignant Brain Tumors

17 enrolled

CNSEndocrine

Brain Neoplasms, Pituitary Neoplasms

NCT02650401 2025-12-24

STARTRK-NG

CNSEndocrineGenitourinaryHead & NeckSarcoma

69 enrolled 1 FDA

Thyroid Cancer, Papillary, Brain Neoplasms, Glioma, Medulloblastoma, Neoplasm Metastasis, Wilms Tumor, Neuroblastoma, Recurrence, Salivary Gland Neoplasms, Sarcoma, Sarcoma, Ewing, Central Nervous System Neoplasms, Nephroma, Mesoblastic

NCT05503251 2025-12-24

Neuropsychological Care for Maintaining Quality of Life After Radiation Therapy in Patients With Brain Metastases

110 enrolled

Brain Neoplasms, Neoplasm Metastasis

NCT05305365 2025-12-23

Study Assessing QBS72S For Treating Brain Metastases

21 enrolled

BreastCNSThoracic

Brain Neoplasms, Breast Neoplasms, Lung Neoplasms, Meningeal Neoplasms

NCT00756639 2025-12-17

Prophylactic Cranial Irradiation (PCI) for Small Cell Carcinoma of the Urothelium

31 enrolled

CNSGenitourinary

Adenocarcinoma, Urinary Bladder Neoplasms, Brain Neoplasms, Carcinoma, Transitional Cell

NCT02910700 2025-12-17

Nivolumab With Trametinib and Dabrafenib, or Encorafenib and Binimetinib in Treating Patients With BRAF Mutated Metastatic or Unresectable Stage III-IV Melanoma

52 enrolled

CNSDermatologic

Brain Neoplasms, Melanoma

NCT05128903 2025-12-15

Quantitative Assessment of Radiation-induced Neuroinflammation - A Proof of Principle Study

22 enrolled

Brain Neoplasms, Medulloblastoma

NCT01358058 2025-12-10

Proton Radiation Therapy for Gliomas

63 enrolled

Brain Neoplasms, Glioma

NCT02374242 2025-12-10

ABC

76 enrolled

CNSDermatologic

Brain Neoplasms, Melanoma, Neoplasm Metastasis

NCT02693990 2025-12-10

A Trial of Increased Dose Intensity Modulated Proton Therapy (IMPT) for High-Grade Meningiomas

21 enrolled

Brain Neoplasms, Meningioma

NCT04538742 2025-12-08

DB-07

245 enrolled

Brain Neoplasms, Breast Neoplasms

NCT01503086 2025-12-05

Computer Training Program for Younger Patients With a Brain Tumor Who Underwent Radiation Therapy

45 enrolled 10 charts

Brain Neoplasms

NCT05267587 2025-12-04

Preop fSRS for Resectable Brain Metastases

49 enrolled

Brain Neoplasms

NCT04163315 2025-12-03

ConnecTC

30 enrolled

Phase EARLY_PHASE1 Active not recruiting

Brain Neoplasms

NCT06209567 2025-12-03

A Study of 68Ga-PSMA-11 PET Scans in People With Brain Tumors

11 enrolled