NCT07416188 2026-03-18
Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma
National Institutes of Health Clinical Center (CC)
Phase 1/2 Not yet recruiting
Clinical Trials
57 trialsNCT07039760 2026-03-11
Asciminib With or Without Sildenafil for Brain Tumors
Washington University School of Medicine
Phase EARLY_PHASE1 Not yet recruiting
NCT07462507 2026-03-10
Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1
Washington University School of Medicine
Phase 2 Not yet recruiting
NCT07458113 2026-03-09
BERLIN
Yale University
Phase 2 Not yet recruiting
NCT07454668 2026-03-06
Trastuzumab Deruxtecan + Stereotactic Radiosurgery (SRS) in HER2+ Breast Cancer Brain Metastases
Baptist Health South Florida
Phase 1 Not yet recruiting
NCT07402343 2026-03-04
T-BRAIN
Maastricht University Medical Center
Phase 2 Not yet recruiting
NCT07449481 2026-03-04
A Single-Arm, Open-Label, Phase II Clinical Study of Utidelone and Bevacizumab With or Without Etoposide in Patients With Brain Metastases From Malignant Solid Tumors
Tianjin Medical University Cancer Institute and Hospital
Phase 2 Not yet recruiting
NCT07210632 2026-02-27
Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)
Vanderbilt-Ingram Cancer Center
Phase EARLY_PHASE1 Not yet recruiting
NCT07439172 2026-02-27
PRC
The Cooper Health System
Phase 2 Not yet recruiting
NCT07428616 2026-02-24
A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma
Exelixis
Phase 2 Not yet recruiting
NCT07271966 2026-02-20
BALANCE
Duke University
Phase NA Not yet recruiting
NCT07384884 2026-02-19
SLITT-GBM
King's College Hospital NHS Trust
Phase NA Not yet recruiting
NCT07415668 2026-02-17
MENTOR
Insel Gruppe AG, University Hospital Bern
Phase NA Not yet recruiting
NCT07278440 2026-02-13
An Exercise Intervention for Improving Mental and Physical Health in Patients With Primary Brain Tumors and Their Caregivers, ET-NEURO Trial
OHSU Knight Cancer Institute
Phase NA Not yet recruiting
NCT07390539 2026-02-05
B7-H3.CD28Z.CART in CNS Neoplasms
Dana-Farber Cancer Institute
Phase 1 Not yet recruiting
NCT07383649 2026-02-03
Trial to Study Anti- HCMV Therapy in Breast Cancer Patients With Progressive Intracranial Metastases and CMV Infection
The Methodist Hospital Research Institute
Phase 2 Not yet recruiting
NCT07376304 2026-01-29
BrainUS-AI
Hospital del Rio Hortega
Phase 3 Not yet recruiting
NCT07365410 2026-01-26
Furmonertinib 160mg vs 80mg + Chemotherapy in EGFR-Mutated NSCLC With Brain Metastases: Efficacy and Safety Study
Tianjin Medical University Cancer Institute and Hospital
Phase 2 Not yet recruiting
NCT06907485 2026-01-21
A Multicenter Study to Assess the Feasibility of 5-Aminolevulinic Acid (5-ALA) in Pediatric Brain Tumor Patients
University of Pittsburgh
Phase 2 Not yet recruiting
NCT07343479 2026-01-15
Sacituzumab Tirumotecan Plus Third-Generation TKI With/Without Radiotherapy for EGFR-Mutant NSCLC Brain Metastases
Zhejiang Cancer Hospital
Phase 2 Not yet recruiting
NCT04745156 2026-01-12
A Study Using Brain Stimulation and Behavioral Therapy to Increase Extent of Resection in Low-Grade Gliomas
Medical College of Wisconsin
Phase NA Not yet recruiting
NCT07329634 2026-01-09
RENESANS
Prof. Franciszek Lukaszczyk Memorial Oncology Center
Phase 3 Not yet recruiting
NCT07331064 2026-01-09
GABRIEL
Medical College of Wisconsin
Phase 1 Not yet recruiting
NCT07313709 2026-01-02
Measuring the Feasibility and Effect of a Virtual Reality Cognitive Training Intervention for Brain Cancer Survivors.
University of Cincinnati
Phase NA Not yet recruiting
NCT07274397 2025-12-10
EARLYBRAINPET
Beta Emitting Accurate Monitored Systems
Phase NA Not yet recruiting
NCT07206849 2025-10-29
Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG)
Nationwide Children's Hospital
Phase 2 Not yet recruiting
NCT07199413 2025-09-30
Allogeneic, Antigen-Presenting, GM-CSF-secreting, SV-BR-1-GM Whole Cell-Therapeutic Vaccine and Immunotherapy: A Phase I Pilot Safety and Feasibility Study for Solid Tumor Patients With CNS Metastases
Medical College of Wisconsin
Phase 1 Not yet recruiting
NCT07197008 2025-09-29
Sacituzumab Tirumotecan (Sac-TMT) Plus Bevacizumab in 3rd Generation EGFR-TKI Treated Advanced EGFR-mutant Nonsquamous NSCLC With Brain Metastasis
Sun Yat-sen University
Phase 2 Not yet recruiting
NCT07177950 2025-09-17
A Two-cohort Study of SHR-A1811 in the Treatment of HER2-positive Breast Cancer With Brain Metastases
Peking University Cancer Hospital & Institute
Phase 1/2 Not yet recruiting
NCT07170436 2025-09-12
BRAIN-MAP
University Hospital, Toulouse
Phase NA Not yet recruiting
NCT07167134 2025-09-11
SISMIC
Centre Paul Strauss
Phase 3 Not yet recruiting
NCT06455189 2025-08-13
Magnetic Resonance Fingerprinting Guided Extended Resection in Glioblastomas
Case Comprehensive Cancer Center
Phase 1 Not yet recruiting
NCT06974370 2025-05-15
ACTION-Brain
University of Vermont Medical Center
Phase 2 Not yet recruiting
NCT06929819 2025-04-16
Research on the Safety and Efficacy of Intraoperative Radiation Therapy in Malignant Cerebral Tumor
First Affiliated Hospital, Sun Yat-Sen University
Phase NA Not yet recruiting
NCT06678867 2025-03-27
P5A
University College, London
Phase 2 Not yet recruiting
NCT06887673 2025-03-20
Lipid Mediators & Cancer: Montelukast, SPM, and Almonds
University of South Florida
Phase EARLY_PHASE1 Not yet recruiting
NCT06863064 2025-03-07
Brain Tumor Surgery and Postoperative Delirium
Kaohsiung Medical University Chung-Ho Memorial Hospital
Phase NA Not yet recruiting
NCT06618703 2025-02-25
BIChE-1
University Hospital, Angers
Phase NA Not yet recruiting
NCT06831695 2025-02-18
Comparison of Surgical Outcomes of Craniotomy and Craniectomy in Posterior Fossa Lesions
University of Health Sciences Lahore
Phase NA Not yet recruiting
NCT06810336 2025-02-05
Pain Control and Quality of Recovery After Intravenous Methadone Versus Intravenous Remifentanil in Craniotomy Surgery
University of Virginia
Phase EARLY_PHASE1 Not yet recruiting
NCT05897658 2024-10-23
LeviTaTe Pilot
Hamilton Health Sciences Corporation
Phase 3 Not yet recruiting
NCT06611306 2024-10-15
BEAT-Breast
Imperial College London
Phase NA Not yet recruiting
NCT06559566 2024-08-19
Evaluation of Postoperative Intracranial Pressure in Patients Undergoing Intracranial Tumor Surgery
Bagcilar Training and Research Hospital
Phase NA Not yet recruiting
NCT06466031 2024-07-30
Application of MET-PET in Fusion With MRI in the Treatment of Glioblastoma Multiforme
Copernicus Memorial Hospital
Phase NA Not yet recruiting
NCT06511323 2024-07-19
Evaluation of Brain Metastases Treated With Stereotactic Radiotherapy Using Dynamic [18F]FDG PET
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Phase NA Not yet recruiting
NCT06483672 2024-07-03
LungBrain001
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Phase 2 Not yet recruiting
NCT06477939 2024-06-27
THREE-GLEES
Institut de cancérologie Strasbourg Europe
Phase 3 Not yet recruiting
NCT06462079 2024-06-17
Sacituzumab Govitecan Combined With Head Radiotherapy for Her2-negative Breast Cancer Brain Metastases
Guangzhou Medical University
Phase 2 Not yet recruiting
NCT06417658 2024-05-16
Comparing Cosmetic Outcomes: Endoscopic vs. Conventional Craniotomy for Frontal Skull Base Lesions
University of Health Sciences Lahore
Phase NA Not yet recruiting
NCT06374888 2024-04-19
Nilatinib Maleate Tablets Combined With Capecitabine in the Treatment of HER2-positive Advanced Esophageal/Esophagogastric Junction/Gastric Adenocarcinoma With Brain Metastases
Convalife (Shanghai) Co., Ltd.
Phase 2 Not yet recruiting