Clinical Trials

Breast Neoplasms

NCT04119024 2026-03-17

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

BreastCNSDermatologicEndocrineHead & NeckNETThoracic

Adenocarcinoma of Lung, Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Breast Neoplasms, Adenoma, Islet Cell, Melanoma, Neoplasm Metastasis, Paraganglioma, Pheochromocytoma, Thyroid Neoplasms, Adrenocortical Carcinoma, Neuroendocrine Tumors

NCT03725436 2026-03-16

ALRN-6924 and Paclitaxel in Treating Patients With Advanced, Metastatic, or Unresectable Solid Tumors

28 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT03742245 2026-03-16

Olaparib in Combination With Vorinostat in Patients With Relapsed/Refractory and/or Metastatic Breast Cancer

28 enrolled

Breast Neoplasms, Neoplasm Metastasis, Recurrence

NCT04253561 2026-03-16

IPATHER

17 enrolled

Breast Neoplasms

NCT06332508 2026-03-13

Pulsed Electromagnetic Fields (PEMFs) - A Highly Selective Breast CAncer Treatment pLatform (PASCAL)

14 enrolled

Breast Neoplasms

NCT07457541 2026-03-12

Molecular Imaging of Fibroblast Activation Protein Expression Using Labeled Technetium-99m HYNIC-FAPI

BreastGastrointestinalThoracic

15 enrolled

Breast Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms

NCT06229392 2026-03-11

A Study to Evaluate the Intratumoral Influenza Vaccine Administration in Patients With Breast Cancer

Phase 1 Withdrawn

Phase 1 Enrolling by invitation

Breast Neoplasms, Influenza, Human, Triple Negative Breast Neoplasms

NCT07080463 2026-03-10

VascuLens RCT

Breast Neoplasms

NCT07454668 2026-03-06

Trastuzumab Deruxtecan + Stereotactic Radiosurgery (SRS) in HER2+ Breast Cancer Brain Metastases

20 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis, Neoplasms

NCT06251544 2026-03-04

TRAIL-R2 and HER2 Bi-Specific Chimeric Antigen Receptor (CAR) T Cells for the Treatment of Metastatic Breast Cancer

27 enrolled

Breast Neoplasms, Mammary Neoplasms, Animal

NCT04270149 2026-02-27

Cancer Peptides Plus GM-CSF and Adjuvant in Breast Cancer

8 enrolled

Breast Neoplasms

NCT03641755 2026-02-23

Olaparib + Sapacitabine in BRCA Mutant Breast Cancer

10 enrolled

Breast Neoplasms

NCT02063724 2026-02-20

Adjuvant

15 enrolled 8 charts

Breast Neoplasms

NCT02157051 2026-02-17

Vaccine Therapy in Treating Patients With HER2-Negative Stage III-IV Breast Cancer

42 enrolled

Breast Neoplasms

NCT02776436 2026-02-17

REDEX

46 enrolled

BreastGenitourinary

Breast Neoplasms, Prostatic Neoplasms

NCT06678269 2026-02-12

A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer

28 enrolled

Breast Neoplasms

NCT05412225 2026-02-11

A Study of an Alternative Treatment Approach (Preoperative Radiotherapy, Then Mastectomy, Then Immediate Reconstruction Surgery) in People With T4 Breast Cancer

Breast Neoplasms

NCT06623396 2026-02-11

A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer

BreastGastrointestinalGynecologic

Adenocarcinoma Of Esophagus, Breast Neoplasms, Diabetes Mellitus, Peritoneal Neoplasms

NCT03237572 2026-02-09

Breast-48

Phase 1 Terminated

13 enrolled 10 charts

Breast Neoplasms

NCT07055854 2026-02-09

MAC

Breast Neoplasms

NCT03740256 2026-02-06

VISTA

BreastGastrointestinalGenitourinaryHead & NeckThoracic

45 enrolled

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Salivary Gland Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT05504707 2026-02-05

DecipHER

30 enrolled

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT07387445 2026-02-04

A Multi-site Pilot Trial of Time Restircted Eating During Chemotheraply for Breast Cancer.

40 enrolled

Intermittent Fasting, Breast Neoplasms, Fasting

NCT06171607 2026-02-02

Contrast Enhanced Ultrasound Medical Imaging for Identifying Breast Masses

100 enrolled

Breast Neoplasms

NCT02999477 2026-01-29

A Study Of Changes In PD-L1 Expression During Preoperative Treatment With Nab-Paclitaxel And Pembrolizumab In Hormone Receptor-Positive Breast Cancer

32 enrolled 23 charts

Breast Neoplasms

NCT05996107 2026-01-28

Study of Ribociclib Administered Concurrently With Postoperative Radiation Therapy in Patients With High-Risk, HR+/HER2- Breast Cancer

30 enrolled

Breast Neoplasms

NCT06966388 2026-01-27

Study to Evaluate the Feasibility of Twice Daily Use of Topical Azelaic Acid in Breast Cancer Patients Undergoing Radiation

33 enrolled

Breast Neoplasms

NCT06324240 2026-01-26

Personalized Vaccine Immunotherapy in Combination With Checkpoint Inhibitor for Treatment of Triple Negative Breast Cancer

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT03863457 2026-01-22

[18F]F-GLN

40 enrolled

Breast Neoplasms

NCT04340180 2026-01-22

Evaluating the Performance of AI in Evaluating Breast MRI Performed With Dose Reduction

20 enrolled

Breast Neoplasms

NCT04360941 2026-01-21

PAveMenT

45 enrolled

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT05633979 2026-01-20

Phase 1b Study of EZH1/2 Inhibitor Valemetostat in Combination With Trastuzumab Deruxtecan in Subjects With HER2 Low/Ultra-low/Null Metastatic Breast Cancer

17 enrolled

Breast Neoplasms

NCT02284919 2026-01-09

ISO-1Primary

30 enrolled

Breast Neoplasms

NCT04521764 2026-01-08

A Vaccine (MV-s-NAP) for the Treatment of Patients With Invasive Metastatic Breast Cancer

54 enrolled

Breast Neoplasms

NCT04616248 2026-01-07

In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors

BreastDermatologicSarcoma

14 enrolled

Bone Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Melanoma, Sarcoma, Osteosarcoma, Carcinoma, Merkel Cell

NCT07300202 2025-12-23

CLINICAL RESEARCH PROTOCOL [A Phase I, Single-arm, Open-label, Dose-escalation Clinical Study to Evaluate the Safety and Tolerability of Orialpha (BD-C) in Healthy Adult Volunteers]

15 enrolled

Breast Neoplasms

NCT03955640 2025-12-22

Hyperthermia and Olaparib in Treating Breast Cancer Patients With Chest Wall Recurrences

Phase 1 Terminated

3 enrolled

Breast Neoplasms

NCT03542175 2025-12-08

A Study of Rucaparib Administered With Radiation in Patients With Triple Negative Breast Cancer With an Incomplete Response Following Chemotherapy

31 enrolled 12 charts

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT03807765 2025-12-04

Stereotactic Radiation and Nivolumab in the Management of Metastatic Breast Cancer Brain Metastases

14 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT06691035 2025-12-04

Immunologic Targeting of ESR1 Receptor for Hormone Receptor Expressing Metastatic Breast Cancer

Breast Neoplasms

NCT02950259 2025-12-03

Pre-operative IRX-2 in Early Stage Breast Cancer (ESBC)

16 enrolled 10 charts

Breast Neoplasms, Breast Neoplasms, Male, Triple Negative Breast Neoplasms

NCT07250386 2025-11-26

PBC102

48 enrolled

BreastThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT02639026 2025-11-25

Trial Of Hypofractionated Radiotherapy In Combination With MEDI4736 And Tremelimumab For Patients With Metastatic Melanoma And Lung, Breast And Pancreatic Cancers

BreastDermatologicGastrointestinalThoracic

53 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms

NCT05900895 2025-11-20

PHOEBE

6 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT06139107 2025-11-14

RADIANT: Pre-op Radiation With Abemaciclib and Letrozole

15 enrolled

Breast Neoplasms

NCT07178665 2025-11-14

Pilot Trial of Preop Partial Radiation in Breast Cancer Patients

Phase 1 Suspended

98 enrolled

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT06959537 2025-11-10

A Phase Ib Study of Novel Combination (New) of Low Dose Oral CyclophoSphamide (s) to Potentiate Axatilimab (A) + Retifanlimab (R) in Treating Metastatic Triple Negative Breast Cancer (TNBC)

24 enrolled

Breast Neoplasms

NCT01552434 2025-10-14

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease