Clinical Trials

Carcinoma, Basal Cell, Melanoma, Carcinoma, Merkel Cell

NCT07482956 2026-03-19

BCC-One-Stop-Study

290 enrolled

Phase 2 Active not recruiting

Carcinoma, Basal Cell, Skin Neoplasms

NCT02834013 2026-03-18

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

818 enrolled

CNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckSarcoma

Nasopharyngeal Carcinoma, Bile Duct Neoplasms, Carcinoma, Basal Cell, Adenocarcinoma, Bronchiolo-Alveolar, Adenocarcinoma, Mucinous, Carcinoma, Transitional Cell, Carcinosarcoma, Chordoma, Carcinoma, Adenoid Cystic, Fibroma, Gallbladder Neoplasms, Hemangiosarcoma, Mouth Neoplasms, Paget Disease, Extramammary, Paraganglioma, Paranasal Sinus Neoplasms, Parathyroid Neoplasms, Pheochromocytoma, Pseudomyxoma Peritonei, Somatostatinoma, Thyroid Neoplasms, Vulvar Neoplasms, Desmoid Tumors, Seminoma, Carcinoma, Acinar Cell, Adrenocortical Carcinoma, Carcinoma, Endometrioid, Cholangiocarcinoma, Cystadenocarcinoma, Mucinous, Cystadenocarcinoma, Serous, Carcinoma, Giant Cell, Neurofibrosarcoma, Gestational Trophoblastic Disease, Rare Diseases, Gastrointestinal Stromal Tumors, Perivascular Epithelioid Cell Neoplasms

NCT02978625 2026-03-18

Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers

Phase 2 Active not recruiting

68 enrolled

DermatologicLymphoid

Microcystic adnexal carcinoma, Adenocarcinoma, Papillary, Carcinoma, Basal Cell, Carcinoma, Basosquamous, Mycosis Fungoides, Paget Disease, Extramammary, Sezary Syndrome, Carcinoma, Merkel Cell, Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Carcinoma, Signet Ring Cell, Muir-Torre Syndrome, Eccrine Porocarcinoma

NCT07241585 2026-03-17

Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT)

54 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell

NCT05814900 2026-03-13

Investigation of Mohs Surgical Margins Using Two Photon Microscopy

135 enrolled 8 charts

Carcinoma, Basal Cell

NCT06981325 2026-03-11

CEMI-first

34 enrolled

Carcinoma, Basal Cell, Skin Neoplasms

NCT06919809 2026-03-09

Effectiveness and Safety of X A-DERM™ Microsurfaced Acellular Dermal Matrix for Wound Healing After MOHS Surgery

16 enrolled

Phase 2 Not yet recruiting

Carcinoma, Basal Cell, Carcinoma, Squamous Cell

NCT07227870 2026-03-09

L19IL2/TNF in Patients With Basal Cell Carcinoma

92 enrolled

Phase 2 Not yet recruiting

Carcinoma, Basal Cell

NCT07455331 2026-03-06

LANCE

60 enrolled

Carcinoma, Basal Cell, Skin Neoplasms

NCT04349436 2026-02-27

ARTACUS

Phase 1/2 Recruiting

90 enrolled

Carcinoma, Carcinoma, Basal Cell, Neoplasms, Skin Neoplasms, Carcinoma, Merkel Cell

NCT07428941 2026-02-24

LegitHealth PH

Completed

9 enrolled

Phase EARLY_PHASE1 Not yet recruiting

Carcinoma, Basal Cell, Melanoma, Nevus, Pigmented, Skin Diseases, Urticaria, Hidradenitis Suppurativa, Keratosis, Actinic

NCT07286318 2026-02-19

A Randomized Controlled Trial of Topical 5% Niacinamide for Skin Cancer Prevention in Transplant Recipients

Phase EARLY_PHASE1 Recruiting

Carcinoma, Basal Cell, Skin Neoplasms, Keratosis, Actinic

NCT07144384 2026-02-13

Intratumoral Injection of Standard Universal Donor Expanded Natural Killer Cells and TGF-beta Imprinted Natural Killer Cells for the Treatment of Skin Squamous Cell Carcinoma and Basal Cell Carcinoma

40 enrolled

Carcinoma, Basal Cell

NCT06624475 2026-02-05

NEON

30 enrolled

Carcinoma, Basal Cell

NCT07182240 2026-02-04

Pilot Study of Line-Field Confocal Optical Coherence Tomography for Detection of Mohs Micrographic Surgery Margins of Basal Cell Carcinomas

Phase NA Recruiting

60 enrolled

Carcinoma, Basal Cell

NCT07384078 2026-02-03

HIFUvsCRYO

294 enrolled

Bowen's Disease, Carcinoma, Basal Cell

NCT06623201 2026-01-29

Blue-Light Photodynamic Therapy and Sonidegib for Multiple Basal Cell Carcinomas

Phase 1 Recruiting

Phase 2 Active not recruiting

Carcinoma, Basal Cell

NCT06422936 2026-01-26

SPOTLIGHT204

60 enrolled

Carcinoma, Basal Cell

NCT07257094 2026-01-26

Nasal Reconstruction FACE-Q : French Validation of the Nasal Reconstruction FACE-Q Questionnaire for Reconstruction/Rehabilitation Following Nasal Skin Cancer

346 enrolled

Carcinoma, Carcinoma, Basal Cell, Carcinoma, Squamous Cell

NCT07361666 2026-01-23

HFUS-CLEAR

Not yet recruiting

400 enrolled

Phase 3 Not yet recruiting

Margins of Excision, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Recurrence, Skin Neoplasms

NCT05212246 2026-01-22

B3C

1,630 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Patient Compliance, Keratosis, Actinic

NCT07358637 2026-01-22

Artificial Intelligence Enhanced Optical Coherence Tomography (AI-OCT) Imaging for Pre-surgical Margin Detection of Basal Cell Carcinoma

Not yet recruiting

30 enrolled

Carcinoma, Basal Cell

NCT03889912 2026-01-21

Intralesional Cemiplimab for Adult Patients With Cutaneous Squamous Cell Carcinoma or Basal Cell Carcinoma

Phase 1 Completed

97 enrolled

Carcinoma, Basal Cell

NCT07347392 2026-01-16

DOSCA-2

Enrolling by invitation

2,900 enrolled

Phase 1 Active not recruiting

Carcinoma, Basal Cell

NCT04616248 2026-01-07

In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors

14 enrolled

BreastDermatologicSarcoma

Bone Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Melanoma, Sarcoma, Osteosarcoma, Carcinoma, Merkel Cell

NCT07311070 2026-01-06

Treatment of Basal Cell Carcinoma (BCC) of the Skin, of the Morpheiform, Infiltrative, and Noduloulcerative Types in Inoperable Patients and Not Suitable for Radiotherapy Using Formulated Methylene Blue

Phase 3 Enrolling by invitation

Carcinoma, Basal Cell

NCT07285044 2025-12-22

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidMyeloidPlasma cellThoracic

27 enrolled

Amyloidosis, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Glioblastoma, Carcinoma, Hepatocellular, Hodgkin Disease, Lung Neoplasms, Melanoma, Multiple Myeloma, Myelodysplastic Syndromes, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Lymphoma, Mantle-Cell

NCT03509467 2025-12-19

Using MC1R Genotype to Impact Melanoma Risk Behavior

2,054 enrolled 92 charts

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Melanoma, Skin Neoplasms, Neoplasms, Basal Cell, Neoplasms, Squamous Cell

NCT06608511 2025-12-17

Liquid Biomarker Study in Melanoma and Non-Melanoma Skin Cancers

Carcinoma, Basal Cell, Melanoma, Skin Neoplasms

NCT03534947 2025-12-16

SONIB

Phase 2 Completed

16 enrolled

Carcinoma, Basal Cell, Skin Neoplasms

NCT03886181 2025-12-08

Alpha Radiation Emitters Device for the Treatment of Cutaneous, Mucosal and Superficial Soft Tissue Neoplasia (DaRT)

Phase NA Terminated

2 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Lip Neoplasms, Sarcoma, Kaposi, Skin Neoplasms, Soft Tissue Neoplasms, Tongue Neoplasms

NCT05859074 2025-12-03

A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer

Phase 1 Recruiting

56 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Hemangiosarcoma, Melanoma, Neoplasm Metastasis, Neoplasms, Paget Disease, Extramammary, Sarcoma, Kaposi, Skin Neoplasms, Carcinoma, Merkel Cell, Adenocarcinoma, Sebaceous, Carcinoma, Skin Appendage

NCT03889899 2025-12-02

Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia.

Phase NA Recruiting

30 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Lip Neoplasms, Sarcoma, Kaposi, Skin Neoplasms, Soft Tissue Neoplasms, Tongue Neoplasms

NCT04540588 2025-12-02

Retreatment With Intratumoral Diffusing Alpha Radiation Emitters

2 enrolled

Phase NA Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Lip Neoplasms, Recurrence, Sarcoma, Kaposi, Skin Neoplasms, Soft Tissue Neoplasms, Tongue Neoplasms

NCT05935995 2025-11-28

HISTOBLOC

42 enrolled

DermatologicHead & Neck

Margins of Excision, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell

NCT05020912 2025-11-26

Alteration of the Immune Microenvironment in Basal Cell Carcinoma Following Photodynamic Therapy

28 enrolled

Carcinoma, Basal Cell

NCT06132191 2025-11-20

Expanded Access Use of Cemiplimab in Patients With Solid Tumors

Approved for marketing

DermatologicThoracic

Carcinoma, Basal Cell, Carcinoma, Non-Small-Cell Lung

NCT07201012 2025-11-17

SMT-SL

DermatologicGastrointestinal

150 enrolled

Carcinoma, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Colorectal Neoplasms, Hereditary Nonpolyposis, Skin Neoplasms, Muir-Torre Syndrome

NCT04272034 2025-10-16

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Phase 1 Terminated

105 enrolled

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Nasopharyngeal Carcinoma, Esophageal Squamous Cell Carcinoma, Anus Neoplasms, Carcinoma, Basal Cell, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Mesothelioma, Neoplasm Metastasis, Carcinoma, Merkel Cell, Endometrial Neoplasms, Small Cell Lung Carcinoma

NCT03836105 2025-10-15

CASE

Completed

287 enrolled

Carcinoma, Basal Cell

NCT05473507 2025-10-09

A Study of Observation and Follow-up in People With Basal Cell Carcinoma

Active not recruiting

26 enrolled

Phase NA Active not recruiting

Carcinoma, Basal Cell

NCT05133427 2025-10-03

BCC-HIFU2101

40 enrolled

Carcinoma, Basal Cell, Skin Neoplasms

NCT06880848 2025-09-24

Sonidegib in Adult Patients With Locally Advanced Basal Cell Carcinoma (laBCC) in China

Phase 4 Completed

160 enrolled

Carcinoma, Carcinoma, Basal Cell

NCT06813833 2025-09-19

RNA-OCT-BCC

Completed

50 enrolled

Carcinoma, Basal Cell, Skin Neoplasms

NCT06536257 2025-09-18

PIP-PREDICT

1,000 enrolled

Carcinoma, Basal Cell, Melanoma, Carcinoma, Merkel Cell

NCT07010692 2025-09-17

Treating Basal and Squamous Cell Carcinomas With Fractional Laser and Tirbanibulin Ointment

Phase 1/2 Recruiting

100 enrolled

Phase NA Active not recruiting

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Skin Neoplasms

NCT07177638 2025-09-17

A Community-based Educational Initiative to Raise Awareness of Melanoma and Other Skin Cancers.

45 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Melanoma, Skin Neoplasms

NCT06600165 2025-09-09

Intraoperative Confocal Laser Scanning Microscopy With Use of AI for Optimized Surgical Excision of Basal Cell Carcinoma

1,000 enrolled

Carcinoma, Basal Cell

NCT06683846 2025-08-24

Ivonescimab in the Treatment of Multiple Advanced Tumors