Clinical Trials

Phase 1/2 Active not recruiting

Carcinoma, Hepatocellular

NCT06084884 2026-03-09

ATHENA

94 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT06486454 2026-03-09

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

Recruiting

5,000 enrolled

Phase 1 Active not recruiting

Carcinoma, Hepatocellular, Liver Neoplasms

NCT03264664 2026-03-06

Study of E7386 in Participants With Selected Advanced Neoplasms

60 enrolled

Carcinoma, Hepatocellular, Neoplasms

NCT03847428 2026-03-06

EMERALD-2

908 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT06096779 2026-03-06

Kirros

30 enrolled

Digestive System Neoplasms, Fatty Liver, Fibrosis, Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms

NCT07164313 2026-03-06

A Study of ZW251 in Participants With Advanced Solid Tumors

100 enrolled

Carcinoma, Hepatocellular

NCT05432492 2026-03-04

A Study of AK112 in Patients With Unresectable Hepatocellular Carcinoma (HCC)

Phase 2 Completed

40 enrolled

Phase NA Active not recruiting

Carcinoma, Hepatocellular

NCT05953337 2026-03-04

Radioembolization Trial Utilizing Eye90 Microspheres™ for the Treatment of Hepatocellular Carcinoma (HCC)

120 enrolled

Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms

NCT06530251 2026-03-04

A Study of AK112 in Patients With Advanced Hepatocellular Carcinoma (HCC)

Phase 1/2 Recruiting

280 enrolled

Carcinoma, Hepatocellular

NCT05063565 2026-03-02

ROWAN

100 enrolled

Adenocarcinoma, Carcinoma, Digestive System Diseases, Digestive System Neoplasms, Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial

NCT06910657 2026-03-02

IDOV-Immune for Advanced Solid Tumors

BreastDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

78 enrolled

Adrenal Gland Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Vaccinia, Colorectal Neoplasms

NCT03833700 2026-02-27

A Study of E7386 in Participants With Advanced Solid Tumor Including Colorectal Cancer (CRC)

Phase 1 Active not recruiting

70 enrolled

EndocrineGastrointestinalNETSarcoma

Gastro-enteropancreatic neuroendocrine tumor, Digestive System Neoplasms, Carcinoma, Hepatocellular, Colorectal Neoplasms, Desmoid Tumors, Adrenocortical Carcinoma

NCT04008797 2026-02-27

A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid Tumor

Phase 1/2 Active not recruiting

301 enrolled

GastrointestinalGynecologic

Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT07284121 2026-02-27

A Study to Evaluate Patient-Reported Satisfaction, Effectiveness, and Safety of Atezolizumab in Participants Treated in Routine Clinical Practice

Recruiting

700 enrolled

GastrointestinalThoracic

Carcinoma, Hepatocellular, Lung Neoplasms

NCT05208762 2026-02-23

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

BreastGastrointestinalGynecologicHead & NeckThoracic

714 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Stomach Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT07377487 2026-02-20

INDIGO

Phase NA Recruiting

51 enrolled

EndocrineGastrointestinalNET

Carcinoma, Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Colorectal Neoplasms, Carcinoma, Neuroendocrine, Neuroendocrine Tumors

NCT04039607 2026-02-19

CheckMate 9DW

732 enrolled 1 FDA

Carcinoma, Hepatocellular

NCT05775159 2026-02-18

Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Hepatobiliary Cancer

294 enrolled

Biliary Tract Neoplasms, Carcinoma, Hepatocellular

NCT07197554 2026-02-18

A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies

GastrointestinalGynecologicSarcoma

171 enrolled

Biliary Tract Neoplasms, Carcinoma, Hepatocellular, Neoplasms, Sarcoma, Ewing, Endometrial Neoplasms

NCT02519348 2026-02-17

A Study of Durvalumab or Tremelimumab Monotherapy, or Durvalumab in Combination With Tremelimumab or Bevacizumab in Advanced Hepatocellular Carcinoma

433 enrolled 26 charts

Carcinoma, Hepatocellular

NCT03463876 2026-02-17

A Trial of SHR-1210 (an Anti-PD-1 Inhibitor) in Combination With Apatinib in Patients With Advanced HCC(RESCUE)

Phase 2 Completed

190 enrolled 15 charts

Carcinoma, Hepatocellular

NCT06600321 2026-02-17

A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

158 enrolled

Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms

NCT06953089 2026-02-06

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

DermatologicGastrointestinalGynecologicHead & NeckThoracic

492 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Melanoma, Ovarian Neoplasms

NCT03713593 2026-02-05

LEAP-002

Phase 3 Completed

794 enrolled 30 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Hepatocellular

NCT06242470 2026-02-05

A Study of MGC026 in Participants With Advanced Solid Tumors

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

250 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Small Cell Lung Carcinoma, Prostatic Neoplasms, Castration-Resistant

NCT06679985 2026-02-05

A Trial of Casdozokitug in Combination With Toripalimab Plus Bevacizumab in Participants With Unresectable and/or Locally Advanced or Metastatic Hepatocellular Carcinoma

72 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT03867084 2026-02-04

KEYNOTE-937

Phase 3 Completed

959 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Hepatocellular

NCT04712643 2026-01-30

A Study of TACE Combined With Atezolizumab Plus Bevacizumab or TACE Alone in Patients With Untreated Heaptocellular Carcionma

342 enrolled

CNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Carcinoma, Hepatocellular

NCT04566393 2026-01-28

Expanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered Malignancies

Available

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Glioblastoma, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT07369505 2026-01-27

Sapu003 in Advanced mTOR-sensitive Solid Tumors

EndocrineGastrointestinalGenitourinaryNET

27 enrolled

Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Tuberous Sclerosis, Neuroendocrine Tumors

NCT07368049 2026-01-26

MR 7700 Multinuclear Application Clinical Study

Phase NA Not yet recruiting

100 enrolled

Carcinoma, Hepatocellular

NCT07348211 2026-01-23

SIM0610-101

GastrointestinalHead & NeckThoracic

260 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Colorectal Neoplasms

NCT04373564 2026-01-22

ODYSSEY

Phase 4 Recruiting

2,076 enrolled

BreastEndocrineGastrointestinalGenitourinaryNET

Breast Neoplasms, Carcinoma, Hepatocellular, Prostatic Neoplasms, Colorectal Neoplasms, Neuroendocrine Tumors

NCT05641896 2026-01-22

18F-FAPI-74 GI

Phase 2 Completed

109 enrolled

Phase 3 Not yet recruiting

Gastrointestinal Neoplasms, Carcinoma, Hepatocellular, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT07356037 2026-01-21

Nanocrystalline Megestrol Acetate for Cachectic Stage Locally Advanced Hepatocellular Carcinoma

68 enrolled

Cachexia, Carcinoma, Hepatocellular

NCT06040099 2026-01-20

EMERALD-Y90

56 enrolled

Phase 1 Active not recruiting

Carcinoma, Hepatocellular, Liver Neoplasms

NCT06084481 2026-01-20

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400

302 enrolled

BreastGastrointestinalHead & Neck

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Biliary Tract Neoplasms, Carcinoma, Hepatocellular, Triple Negative Breast Neoplasms

NCT06653023 2026-01-20

Wondercel-UWD3

Phase EARLY_PHASE1 Recruiting

60 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular

NCT06689670 2026-01-20

Needle-based Percutaneous Ablation of Liver Tumors.

Phase NA Recruiting

31 enrolled

Carcinoma, Hepatocellular, Neoplasms

NCT03778957 2026-01-16

EMERALD-1

724 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT03228667 2026-01-14

QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors