Clinical Trials

Carcinoma, Non-Small-Cell Lung

NCT05431270 2025-01-31

Dose Escalation/Expansion Study of Mavrostobart (PT199), an Anti-CD73 MAb, Administered Alone and in Combination with a PD-1 Inhibitor or Chemotherapy (the MORNINGSTAR Study)

Phase 1/2 Recruiting

40 enrolled

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT06467617 2024-12-16

Adebrelimab Plus Chemo and Recaticimab in Perioperative Treatment of Resectable NSCLC

Phase 2 Recruiting

35 enrolled

Phase 3 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT04956692 2024-12-03

MK-3475-A86

531 enrolled 18 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Non-Small-Cell Lung

NCT05501665 2024-10-17

Split Course Adaptive Radiation Therapy With Pembrolizumab With/Without Chemotherapy for Treating Stage IV Lung Cancer

Phase 1/2 Recruiting

25 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02775435 2024-10-08

KEYNOTE-407

559 enrolled 18 charts 1 FDA

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Non-Small-Cell Lung

NCT02250326 2024-09-19

abound2L+

240 enrolled 23 charts

Phase 2 Not yet recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms

NCT06475755 2024-06-26

Neoadjuvant/Adjuvant Tislelizumab Combined With Anlotinib and Platinum Doublet Chemotherapy With Resectable NSCLC

178 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05377658 2024-02-21

AK104 With Chemotherapy as Neoadjuvant and Adjuvant Therapy for Resectable Non-small Cell Lung Cancer

Phase 2 Recruiting

43 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02716038 2023-12-12

Neoadjuvant MPDL3280A, Nab-paclitaxel and Carboplatin (MAC) in NSCLC

39 enrolled 8 charts

Carcinoma, Non-Small-Cell Lung

NCT02710396 2023-07-24

Genetic Predictors of Benefit to Pembrolizumab

Phase 2 Terminated

19 enrolled 12 charts

Carcinoma, Non-Small-Cell Lung

NCT03345810 2023-06-15

DURATION

200 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02382406 2023-05-23

Carboplatin/Nab-Paclitaxel and Pembrolizumab in NSCLC

Phase 1/2 Terminated

46 enrolled 24 charts

DermatologicHead & NeckLymphoidThoracic

Carcinoma, Non-Small-Cell Lung

NCT02376699 2023-05-01

Safety Study of SEA-CD40 in Cancer Patients

Phase 1 Terminated

159 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Hodgkin Disease, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Neoplasm Metastasis, Neoplasms, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse, Neoplasms, Squamous Cell

NCT03138889 2023-03-10

PROPEL

Phase 1/2 Terminated

162 enrolled 21 charts

Carcinoma, Non-Small-Cell Lung

NCT04338620 2023-03-06

Camrelizumab Combined With Albumin-bound Paclitaxel and Platinum in Neoadjuvant Treatment of Resectable NSCLC

Phase 2 Unknown

94 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02039674 2022-11-08

MK-3475-021

Phase 1/2 Completed

267 enrolled 24 charts

Carcinoma, Non-Small-Cell Lung

NCT02967133 2022-09-08

A Study of Nivolumab +/- Nab-paclitaxel in Non-small Cell Lung Cancer

Phase 2 Terminated

7 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung

NCT00347412 2022-07-25

Study of NOV-002 in Combination With Chemotherapy to Treat Lung Cancer

903 enrolled

Carcinoma, Non-Small-Cell Lung, Pericardial Effusion

NCT04459611 2022-07-12

neoSCORE

Phase 2 Unknown

60 enrolled

Carcinoma, Non-Small-Cell Lung

NCT00533949 2022-06-21

High-Dose or Standard-Dose Radiation Therapy and Chemotherapy With or Without Cetuximab in Treating Patients With Newly Diagnosed Stage III Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery

544 enrolled 21 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Radiation Injuries

NCT02662634 2022-03-18

A Safety and Feasibility Study of AGS-003-LNG for the Treatment of Stage 3 Non Small Cell Lung Cancer

Phase 2 Withdrawn

Carcinoma, Non-Small-Cell Lung

NCT02799862 2021-10-06

NEPTUN

Completed

408 enrolled

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT01620190 2021-07-16

Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Previously Treated Advanced Non-small Cell Lung Cancer

26 enrolled 12 charts

Phase 2 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT04304248 2021-05-06

NeoTAP01

30 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04725448 2021-04-06

Toripalimab Combined With Bevacizumab, Nab-paclitaxel and Carboplatin for Untreated Metastatic Pulmonary Sarcomatoid Carcinoma

Phase 2 Unknown

27 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Diseases, Thoracic Neoplasms

NCT02392507 2020-11-19

A Study of Nab-Paclitaxel and Carboplatin Plus Necitumumab (LY3012211) in Participants With Stage IV Squamous NSCLC

54 enrolled 16 charts

Carcinoma, Carcinoma, Non-Small-Cell Lung

NCT02730247 2020-11-19

Clinical Trial of the Safety and Efficacy of the Addition of Ramucirumab to Nab-paclitaxel in Previously Treated Patients With Advanced Non-small Cell Lung Cancer (NSCLC)

7 enrolled 16 charts

Carcinoma, Non-Small-Cell Lung

NCT01702844 2020-10-08

Single Arm on the Tolerability of Weekly Nab-paclitaxel

42 enrolled 20 charts

Carcinoma, Non-Small-Cell Lung

NCT02027428 2020-08-17

Safety and Efficacy Study of Abraxane as Maintenance Treatment After Abraxane Plus Carboplatin in 1st Line Stage IIIB / IV Squamous Cell Non-small Cell Lung Cancer

427 enrolled 29 charts

Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Lung Neoplasms

NCT00274443 2019-11-12

An Open Label Study in Patients With Advanced NSCLC With ABI-007(Abraxane) in Combination With Carboplatin

250 enrolled

GastrointestinalGenitourinaryGynecologicThoracic

Carcinoma, Non-Small-Cell Lung

NCT01478685 2019-11-12

A Phase 1 Study of CC-486 as a Single Agent and in Combination With Carboplatin or ABI-007 in Subjects With Relapsed or Refractory Solid Tumors

Phase 1 Completed

169 enrolled

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Fallopian Tube Neoplasms, Ovarian Neoplasms, Peritoneal Neoplasms, Recurrence, Tumor Virus Infections, Carcinoma, Pancreatic Ductal

NCT04153734 2019-11-06

Evolution

Phase 2 Not yet recruiting

21 enrolled

Carcinoma, Non-Small-Cell Lung

NCT00540514 2019-10-29

Albumin-bound Paclitaxel (ABI-007) for Patients With Advanced Non-Small Cell Lung Cancer

1,052 enrolled 31 charts

BreastGastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung

NCT02309177 2019-05-31

Safety Study of Nivolumab With Nab-Paclitaxel Plus or Minus Gemcitabine in Pancreatic Cancer, Nab-Paclitaxel / Carboplatin in Stage IIIB/IV Non-Small Cell Lung Cancer or Nab-Paclitaxel in Recurrent Metastatic Breast Cancer

Phase 1 Completed

114 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pancreatic Neoplasms, Triple Negative Breast Neoplasms

NCT02289456 2018-12-07

AboundPS2

40 enrolled 24 charts

Carcinoma, Non-Small-Cell Lung

NCT02151149 2018-09-24

ABOUND 70+

Phase 4 Completed

143 enrolled 25 charts

Adenocarcinoma, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Lung Neoplasms, Carcinoma, Large Cell

NCT00470548 2018-01-10

Abraxane and Alimta in Advanced Solid Tumors

Phase 1/2 Terminated

49 enrolled 10 charts

BreastThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Breast Neoplasms, Male

NCT02172846 2017-12-08

Hypofractionated Proton Beam Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With Stage II-III Non-Small Cell Lung Cancer

Phase 1 Completed

23 enrolled