NCT05488314 2026-03-13METalmarkJanssen Research & Development, LLCPhase 1/2 Active not recruiting57 enrolled
NCT05110196 2025-12-03Study of Capmatinib in Indian Patients With MET Exon 14 Skipping Mutation Positive Advanced NSCLC.NovartisPhase 4 Completed50 enrolled
NCT04575025 2025-09-15Special Drug Use-results Surveillance of Tabrecta TabletsNovartisCompleted109 enrolled
NCT05703516 2025-01-14A Post Approval Commitment Study on Tabrecta® (Capmatinib) in South KoreaNovartisRecruiting250 enrolled
NCT04139317 2024-10-09Safety and Efficacy of Capmatinib (INC280) Plus Pembrolizumab vs Pembrolizumab Alone in NSCLC With PD-L1≥ 50%NovartisPhase 2 Terminated76 enrolled 17 charts
NCT04323436 2024-10-09Study of Capmatinib and Spartalizumab/Placebo in Advanced NSCLC Patients With MET Exon 14 Skipping MutationsNovartisPhase 2 Terminated31 enrolled 21 charts
NCT02414139 2024-03-20Study of Oral cMET Inhibitor INC280 in Patients With EGFR Wild-type (wt), Advanced Non-small Cell Lung Cancer (NSCLC) (Geometry Mono-1)NovartisPhase 2 Completed373 enrolled 34 charts 3 FDA
NCT02335944 2023-06-18Study of Safety and Efficacy of EGFR-TKI EGF816 in Combination With cMET Inhibitor INC280 in Adult Patients With EGFR Mutated Non Small Cell Lung Cancer.NovartisPhase 1/2 Terminated177 enrolled 48 charts
NCT05675683 2023-01-09Real-World Assessment of Clinical Outcomes in Metastatic NSCLC Patients With MET Exon 14 Skipping Mutation and Brain Metastases Treated With CapmatinibNovartisCompleted68 enrolled
NCT02323126 2022-02-28Study of Efficacy and Safety of Nivolumab in Combination With EGF816 and of Nivolumab in Combination With INC280 in Patients With Previously Treated Non-small Cell Lung CancerNovartisPhase 2 Terminated64 enrolled 28 charts
NCT03647488 2022-01-24Study of Capmatinib and Spartalizumab Combination Therapy vs Docetaxel in Non-small Cell Lung CancerNovartisPhase 2 Completed18 enrolled 23 charts
NCT01610336 2021-04-08A Safety and Efficacy Study of INC280 and Gefitinib in Patients With EGFR Mutated, c-MET-amplified NSCLC Who Have Progressed After EGFRi TreatmentNovartisPhase 2 Completed161 enrolled 32 charts
NCT04460729 2020-12-03A Phase II, Open-Label, Multicenter Study of Capmatinib in Subjects With MET Exon 14 Skipping Mutation Positive, Advanced, NSCLC With Brain MetastasesNovartisPhase 2 Withdrawn