Clinical Trials Browser

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Noonan Syndrome, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT05379985 2025-11-12

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

Phase 1/2 Recruiting

754 enrolled

DermatologicGastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Gastrointestinal Neoplasms, Intestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplastic Processes, Pancreatic Neoplasms, Thoracic Neoplasms, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT05293496 2025-10-14

A Study of MGC018 in Combination With MGD019 in Participants With Advanced Solid Tumors

Phase 1 Completed

31 enrolled

DermatologicGastrointestinalGenitourinaryGynecologic

Carcinoma, Ovarian Epithelial, Carcinoma, Renal Cell, Liver Neoplasms, Melanoma, Carcinoma, Pancreatic Ductal, Prostatic Neoplasms, Castration-Resistant

NCT05461430 2025-09-15

TraveraRTGx

Recruiting

200 enrolled

BreastDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

Anus Neoplasms, Appendiceal Neoplasms, Ascites, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Laryngeal Neoplasms, Lung Neoplasms, Melanoma, Mesothelioma, Mouth Neoplasms, Nasopharyngeal Neoplasms, Neoplasms, Unknown Primary, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Penile Neoplasms, Stomach Neoplasms, Thymoma, Vulvar Neoplasms, Pleural Effusion, Malignant, Carcinoma, Neuroendocrine, Cholangiocarcinoma, Carcinoma, Small Cell, Carcinoma, Pancreatic Ductal, Gastrointestinal Stromal Tumors

NCT07153289 2025-09-03

ResCPa

Phase 1/2 Not yet recruiting

38 enrolled

Gastrointestinal

Pancreatic Neoplasms, Carcinoma, Pancreatic Ductal

NCT03856658 2025-06-17

Hepatic Artery Infusional Floxuridine to Treat Pancreatic Cancer Liver Metastases

Phase 2 Active not recruiting

14 enrolled

Gastrointestinal

Pancreatic Neoplasms, Carcinoma, Pancreatic Ductal

NCT04121286 2025-05-20

A Study of JAB-3312 in Adult Patients With Advanced Solid Tumors in China

Phase 1 Completed

17 enrolled

BreastGastrointestinalHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Noonan Syndrome, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT05288205 2025-04-04

Phase 1/2a Study of JAB-21822 Plus JAB-3312 in Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation

Phase 1/2 Recruiting

240 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

Clinical Trials

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene.

ENACT

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

Relacorilant With Nab-Paclitaxel and Gemcitabine in Patients With Metastatic Pancreatic Adenocarcinoma

PACsign

A Clinical Trial of PF-08046037 Alone or With Sasanlimab in Patients With Advanced or Metastatic Malignancies

A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors