Clinical Trials

Phase 1 Active not recruiting

Carcinoma, Squamous Cell, Oropharyngeal Neoplasms

NCT04391049 2026-01-30

Testing the Addition of the Anti-cancer Viral Therapy Telomelysin™ to Chemoradiation for Patients With Advanced Esophageal Cancer and Are Not Candidates for Surgery

16 enrolled 15 charts

Carcinoma, Squamous Cell, Neoplasms, Squamous Cell

NCT02819752 2026-01-21

PEACH

Phase 1 Terminated

3 enrolled 12 charts

Phase 2 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell

NCT01512589 2025-10-10

Proton Beam Therapy (PBT) Versus Intensity-Modulated Radiation Therapy (IMRT) Trial

147 enrolled

Phase 2 Active not recruiting

Adenocarcinoma, Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT05574101 2025-08-08

A Study of Radiation Therapy and Cemiplimab for People With Skin Cancer

34 enrolled

Dermatologic

Carcinoma, Squamous Cell, Skin Neoplasms

NCT06940180 2025-06-26

Toripalimab With Chemotherapy for Sinus Cancer

Phase 2 Recruiting

20 enrolled

Sinonasal undifferentiated carcinoma, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Paranasal Sinus Neoplasms

NCT05608369 2025-04-04

HPV

Phase 2 Withdrawn

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell

NCT05784012 2025-03-13

RADIAN

Phase 1/2 Recruiting

34 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Laryngeal Diseases, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT03715946 2025-01-13

Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer

40 enrolled 69 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms

NCT03641547 2024-07-18

CHARIOT

36 enrolled 24 charts

Adenocarcinoma Of Esophagus, Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT02285543 2023-11-22

A Phase II Trial of TPF Induction Chemotherapy in cN2 OSCC Patients

10 enrolled

Carcinoma, Squamous Cell, Mouth Neoplasms

NCT02229656 2023-11-07

Olaparib and Radiotherapy in Head and Neck Cancer

Phase 1 Unknown

12 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Neoplasms

NCT02158234 2023-01-19

Stereotactic Body Radiotherapy and Concurrent Cisplatin for Re-Irradiation of Unresectable, Recurrent Squamous Cell Carcinomas of Head and Neck

20 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Diseases

NCT02357992 2022-10-14

Lung Cancer STARS Trial - STARS Revised Clinical Trial Protocol: Stereotactic Ablative Radiotherapy (SABR) in Stage I Non-small Cell Lung Cancer Patients Who Can Undergo Lobectomy

Phase NA Completed

122 enrolled 10 charts

EndocrineThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Lung Neoplasms, Carcinoma, Neuroendocrine

NCT00573131 2022-06-22

Efficacy and Safety of OncoGel™ Added to Chemotherapy and Radiation Before Surgery in Subjects With Esophageal Cancer

137 enrolled 9 charts

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Carcinoma, Squamous Cell, Esophageal Neoplasms, Neoplasms

NCT00660218 2021-11-08

A Phase I/II Study of Radiation Therapy, Paclitaxel Poliglumex and Cetuximab in Advanced Head and Neck Cancer

Phase 1/2 Completed

53 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT01077999 2021-04-21

Chemoradiation and Panitumumab for Esophageal Cancer

78 enrolled

Adenocarcinoma, Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT01217060 2021-04-13

Trimodality Management of T1b Esophageal Cancers

Phase 1/2 Completed

4 enrolled 8 charts

Adenocarcinoma, Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT02526953 2021-02-09

Efficacy Study of Chemoradiotherapy With or Without Paclitaxel in Squamous-cell Anal Carcinoma Patients

Phase 3 Unknown

314 enrolled

Anus Diseases, Anus Neoplasms, Carcinoma, Carcinoma, Squamous Cell, Neoplasms, Neoplasms, Squamous Cell

NCT01445405 2019-12-17

Radiation Therapy and Bortezomib and Cetuximab With or Without Cisplatin to Treat Head and Neck Cancer

3 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Pharyngeal Neoplasms

NCT00011778 2019-12-12

PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck

25 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT00563784 2019-11-20

TARCEVA (Erlotinib) in Combination With Chemoradiation in Patients With Stage IIIA/B Non-Small Cell Lung Cancer (NSCLC)

68 enrolled 11 charts

Thoracic

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Lung Neoplasms, Adenocarcinoma, Clear Cell, Carcinoma, Giant Cell

NCT00389727 2019-07-15

Simultaneous Integrated Boost (SIB)- IMRT

22 enrolled

Tumor-Agnostic

Carcinoma, Squamous Cell

NCT01511081 2017-12-07

Stereotactic Body Radiotherapy (SBRT) Versus Stereotactic Body Proton Therapy (SBPT)

21 enrolled 5 charts

Thoracic

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Recurrence, Carcinoma, Large Cell

NCT00490061 2017-03-06

Lapatinib and Radiation for Stage III-IV Head and Neck Cancer Patients Who Cannot Tolerate Concurrent Chemotherapy

17 enrolled 7 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT00937612 2017-02-08

Postoperative Concurrent Chemoradiation for Head and Neck Cancer With Multiple Minor Risk

Phase NA Terminated

10 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT02985255 2016-12-07

Role of Neo-adjuvant Chemotherapy in Tongue Preservation in Locally Advanced Squamous Cell Carcinoma of Oral Tongue

Phase 2 Unknown

30 enrolled

Carcinoma, Squamous Cell, Tongue Neoplasms

NCT00101582 2016-09-27

Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer

Phase 3 Completed

188 enrolled 19 charts

Head & NeckOther

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Diseases, Stomatitis, Xerostomia, Oral Ulcer, Mucositis

NCT01232374 2015-08-20

Nimotuzumab in Combination With Chemoradiation for Local Advanced Esophageal Squamous Cell Carcinoma

Phase 2 Unknown

144 enrolled

Tumor-Agnostic

Carcinoma, Squamous Cell

NCT00113347 2012-02-27

Erlotinib and Docetaxel With Concomitant Boost Radiation Therapy (XRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)

10 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT00233636 2011-01-27

Iressa and Radiotherapy in the Treatment of the Locally Advanced Inoperable Squamous Cell Carcinoma of the Head and Neck

Phase 2 Withdrawn

28 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT00751543 2010-06-29

The Character of Perfusion Parameters Derived From MDCT Between Adenocarcinoma and Squamous Cell Carcinoma of Lung in the Treatment Course of Radiation Therapy

Phase NA Unknown

20 enrolled

Tumor-Agnostic

Adenocarcinoma, Carcinoma, Squamous Cell

NCT00094081 2010-02-15

Concomitant Radiation and Cisplatin With and Without Tirapazamine in Treatment of Advanced Head and Neck Cancer

Phase 3 Completed

861 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Diseases

NCT00229723 2009-08-04

IRESSA™ (Gefitinib) With Cisplatin Plus Radiotherapy for the Treatment of Previously Untreated Unresected Late Stage III/IV Non-Metastatic Head and Neck Squamous Cell Carcinoma

224 enrolled 21 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Neoplasms, Squamous Cell

NCT00197444 2009-02-20

Low-Dose Nedaplatin (CDGP:Cis-Diammine-Glycolatoplatinum)/5-FU Combined With Radiation for Esophageal Cancer

33 enrolled

Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT00001442 2008-03-04

A Pilot Study of Paclitaxel With Radiation Therapy for Locally Advanced Head and Neck Cancer

35 enrolled