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Carcinoma × binimetinib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Conditions

Melanoma 39 Carcinoma, Non-Small-Cell Lung 15 Lung Neoplasms 10 Colorectal Neoplasms 10 Neoplasm Metastasis 9 Neoplasms 8 Brain Neoplasms 8 Pancreatic Neoplasms 6 Triple Negative Breast Neoplasms 5 Skin Neoplasms 5 Uveal Melanoma 3 Ovarian Neoplasms 3 Gastrointestinal Stromal Tumors 3 Biliary Tract Neoplasms 3 Thyroid Neoplasms 2 Skin Diseases 2 Recurrence 2 Rectal Neoplasms 2 Neurofibromatosis 1 2 Multiple Myeloma 2 Leukemia, Hairy Cell 2 Hereditary Sensory and Autonomic Neuropathies 2 Hematologic Neoplasms 2 Glioma 2 Fallopian Tube Neoplasms 2 Colonic Neoplasms 2 Breast Neoplasms 2 Spinocerebellar Degenerations 1 Solid Tumors Harboring a BRAF V600 Mutation 1 Solid Tumors 1

Interventions

Cisplatin 46 Carboplatin 43 pembrolizumab 39 Paclitaxel 38 Gemcitabine 27 Radiotherapy 19 Pemetrexed 19 Magnetic Resonance Spectroscopy 18 Radiotherapy, Intensity-Modulated 17 Docetaxel 17 Cetuximab 16 Specimen Handling 15 Nivolumab 15 Cyclophosphamide 14 durvalumab 13 Fluorouracil 13 Sorafenib 10 Bevacizumab 10 130-nm albumin-bound paclitaxel 10 Sunitinib 9 Platinum 9 osimertinib 8 Radiation 8 Oxaliplatin 8 Irinotecan 8 Everolimus 8 Capecitabine 8 1,2-diaminocyclohexaneplatinum II citrate 8 Ipilimumab 7 Drug Therapy 7

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT02185690 2025-08-21

MEK162

University Health Network, Toronto

Phase 1 Completed

13 enrolled 11 charts

Carcinoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

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