Clinical Trials

90 enrolled

Breast

Breast Neoplasms, Carcinoma, Neoplasms

NCT07408635 2026-02-13

IBI363 (PD-1/IL-2α-bias) in Combination With Chemotherapy as Neoadjuvant Therapy in Initially Unresectable Stage III Non-Small Cell Lung Cancer

43 enrolled

Thoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung

NCT06027086 2026-02-12

DRP-104 (Glutamine Antagonist) in Combination With Durvalumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)

27 enrolled

Fibrolamellar hepatocellular carcinoma, Carcinoma

NCT06636734 2026-02-11

Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial

28 enrolled

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT00349830 2026-02-10

Novel Serum Markers for Monitoring Response to Anti-Cancer Therapy

2,000 enrolled

Adenocarcinoma, Carcinoma, Neoplasms

NCT06532279 2026-02-02

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

98 enrolled

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms, Stomatitis

NCT07257094 2026-01-26

Nasal Reconstruction FACE-Q : French Validation of the Nasal Reconstruction FACE-Q Questionnaire for Reconstruction/Rehabilitation Following Nasal Skin Cancer

346 enrolled

Dermatologic

Carcinoma, Carcinoma, Basal Cell, Carcinoma, Squamous Cell

NCT06612827 2025-12-24

OCAPI

20 enrolled

Carcinoma

NCT05917106 2025-12-11

Renal Cancer Monitoring Based on ctDNA Methylomics: A Prospective Cohort Study (MEMORY Study)

450 enrolled

Genitourinary

Carcinoma, Carcinoma, Renal Cell, Kidney Neoplasms

NCT06564623 2025-12-05

Targeting Driver Oncogenes With a Peptide Vaccine Plus Durvalumab and Tremelimumab for Patients With Biliary Tract Cancers (BTC)

Phase 1 Recruiting

25 enrolled

Diabetes Mellitus, Insulin-Dependent, 12, Biliary Tract Neoplasms, Carcinoma

NCT06676527 2025-12-05

Vorolanib in the Second-line Treatment of Patients With Unresectable or Metastatic Renal Cell Carcinoma

39 enrolled

Genitourinary

Urogenital Diseases, Carcinoma, Carcinoma, Renal Cell, Kidney Diseases, Kidney Neoplasms, Neoplasms, Urogenital Neoplasms, Urologic Diseases, Urologic Neoplasms, Female Urogenital Diseases, Male Urogenital Diseases

NCT06001658 2025-12-03

Perioperative Gemcitabine, Cisplatin, and Pembrolizumab in Potentially Resectable Biliary Tract Cancers

27 enrolled

Biliary Tract Neoplasms, Carcinoma

NCT06782932 2025-12-03

Comparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectable Pancreatic Cancer

38 enrolled

Adenocarcinoma, Carcinoma, Pancreatic Neoplasms

NCT06941857 2025-12-03

NC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in Patients With Untreated Metastatic Pancreatic Cancer

20 enrolled

Carcinoma, Pancreatic Neoplasms

NCT07252323 2025-11-26

A Single-arm Phase II Clinical Study Investigating the Safety and Efficacy of Carbon Ion Radiotherapy in Patients With Hepatocellular Carcinoma Previously Treated With Transarterial Radioembolization (TARE)

48 enrolled

Carcinoma, Carcinoma, Hepatocellular

NCT07246668 2025-11-24

A Phase II Single-Arm Clinical Study to Evaluate the Efficacy and Safety of Carbon Ion Radiotherapy With Atezolizumab and Bevacizumab Combination Therapy in Patients With Advanced Hepatocellular Carcinoma

52 enrolled

Carcinoma, Carcinoma, Hepatocellular, Liver Neoplasms

NCT05541016 2025-11-04

De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNA

455 enrolled

Carcinoma, Oropharyngeal Neoplasms

NCT06445114 2025-11-04

Using CircuLating Tumor DNA to Risk Adapt Post-Operative Therapy for HPV-associated Oropharyngeal Cancer

50 enrolled

Carcinoma, Oropharyngeal Neoplasms

NCT03010150 2025-11-03

Blood Tests and Questionnaires in Studying Adherence to Preventative Swallowing Exercises in Participants With Metastatic Head and Neck Cancer

471 enrolled

CNSDermatologicGastrointestinalGenitourinarySarcoma

Nasopharyngeal Carcinoma, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Neoplasms, Unknown Primary, Oropharyngeal Neoplasms

NCT04897321 2025-10-24

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

Phase 1 Recruiting

32 enrolled

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT07145801 2025-10-07

TARE

30 enrolled

Carcinoma, Carcinoma, Hepatocellular, Liver Neoplasms

NCT06096688 2025-09-04

Discovering New Targets for Colorectal and Endometrial Cancer Risk Reduction

GastrointestinalGynecologic

1,120 enrolled

Carcinoma, Neoplastic Syndromes, Hereditary, Polyps, Colorectal Neoplasms, Endometrial Neoplasms

NCT06683846 2025-08-24

Ivonescimab in the Treatment of Multiple Advanced Tumors

CNSDermatologicEndocrineGenitourinarySarcoma

400 enrolled

Urachal cancer, Carcinoma, Carcinoma, Basal Cell, Carcinoma, Transitional Cell, Kidney Neoplasms, Paget Disease, Extramammary, Paraganglioma, Penile Neoplasms, Pheochromocytoma, Prostatic Neoplasms, Rhabdomyosarcoma, Sarcoma, Angiomyolipoma, Carcinoma, Neuroendocrine, Perivascular Epithelioid Cell Neoplasms

NCT05457595 2025-08-06

CYCLOPS

55 enrolled

Gynecologic

Carcinoma, Ovarian Neoplasms, Recurrence, Vulvar Neoplasms

NCT03370406 2025-06-15

Intralesional 5-Fluorouracil (5FU), Topical Calcipotriene Treatment for SCC

Phase 1 Recruiting

30 enrolled

Carcinoma, Carcinoma, Squamous Cell

NCT06279143 2025-05-20

dOCT-pBCC

210 enrolled

Dermatologic

Carcinoma, Carcinoma, Basal Cell, Eyelid Diseases, Eyelid Neoplasms, Hypersensitivity, Neoplasms, Glandular and Epithelial, Recurrence, Skin Diseases, Skin Neoplasms

NCT06969534 2025-05-15

Safety and Efficacy of Pucotenlimab in pLECC

33 enrolled

Carcinoma

NCT05559879 2025-05-04

Cabozantinib and Dostarlimab in Recurrent Gynecologic Carcinosarcoma

37 enrolled

Gynecologic

Carcinoma, Uterine Neoplasms, Endometrial Neoplasms

NCT06950814 2025-04-30

Prognostic Impact of Adjuvant Therapy in Primary Hepatic Sarcomatoid Carcinoma

50 enrolled

Carcinoma, Liver Neoplasms

NCT06833229 2025-04-11

FDG Immun Comb

200 enrolled

Thoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung

NCT06662058 2025-04-10

Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation

118 enrolled

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT05297734 2025-03-19

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicMyeloidSarcomaThoracic

2,996 enrolled

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Death, Esophageal Neoplasms, Glioblastoma, Lung Diseases, Lung Neoplasms, Melanoma, Myelodysplastic Syndromes, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Sarcoma, Osteosarcoma, Skin Neoplasms, Stomach Neoplasms, Thoracic Neoplasms, Urogenital Neoplasms, Disease Progression, Small Cell Lung Carcinoma

NCT04261855 2025-02-14

GoTHAM

19 enrolled

DermatologicEndocrineNET

Carcinoma, Carcinoma, Merkel Cell, Neuroendocrine Tumors

NCT06827353 2025-02-14

OVNI-B

300 enrolled

Gynecologic

Carcinoma, Ovarian Neoplasms

NCT03708224 2025-01-28

Preoperative Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck

55 enrolled

Carcinoma, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Neoplasms

NCT05917158 2025-01-22

1

30 enrolled

Phase EARLY_PHASE1 Recruiting

Carcinoma

NCT05141474 2024-11-07

NEXTGENTIL-ACT

10 enrolled

Carcinoma

NCT04747054 2024-10-26

PembroMetaRT

Phase 3 Recruiting

102 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Carcinoma, Squamous Cell, Neoplasm Metastasis

NCT02292641 2024-10-17

Beyond TME Origins

383 enrolled

Adenocarcinoma, Carcinoma, Neoplasms

NCT06380816 2024-08-20

A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer