Completed × Has results × Central Nervous System Neoplasms × Clear all Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab
Phase 2 Completed
35 enrolled 13 charts
Preventative Skin Care for Children Undergoing Targeted CNS Tumor Therapy
Phase 2 Completed
14 enrolled 6 charts
Selumetinib Sulfate in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)
Phase 2 Completed
21 enrolled 11 charts
A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent Glioblastoma
Phase 1/2 Completed
116 enrolled 31 charts
Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)
Phase 2 Completed
20 enrolled 12 charts
Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)
Phase 2 Completed
18 enrolled 12 charts
Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)
Phase 2 Completed
4 enrolled 12 charts
Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas
Phase 1 Completed
59 enrolled 20 charts
Nanoparticle Albumin-Bound Rapamycin, Temozolomide, and Irinotecan Hydrochloride in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors
Phase 1 Completed
33 enrolled 15 charts
Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)
Phase 2 Completed
6 enrolled 12 charts
Pevonedistat, Irinotecan, and Temozolomide in Treating Patients With Recurrent or Refractory Solid Tumors or Lymphoma
Phase 1 Completed
30 enrolled 19 charts
Temozolomide and Radiation Therapy in Treating Patients With Gliomas
Phase 2 Completed
136 enrolled 9 charts
Study of Tozuleristide and the Canvas Imaging System in Pediatric Subjects With CNS Tumors Undergoing Surgery
Phase 2/3 Completed
118 enrolled 21 charts
A Study of Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors
Phase 2 Completed
53 enrolled 18 charts
Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer
Phase 2 Completed
78 enrolled 11 charts
Treatment of Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor
Phase 3 Completed
416 enrolled 16 charts
Cabozantinib S-Malate in Treating Younger Patients With Recurrent or Refractory Solid Tumors
Phase 1 Completed
41 enrolled 20 charts
Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Detecting Lactate and Bicarbonate in Participants With Central Nervous System Tumors
Phase 1 Completed
9 enrolled 6 charts
Prexasertib in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors
Phase 1 Completed
30 enrolled 16 charts
Intensive Chemotherapy and Autotransplantation for Patients With Newly Diagnosed Anaplastic Oligodendroglioma
Phase 2 Completed
60 enrolled 9 charts
Entinostat in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors
Phase 1 Completed
21 enrolled 15 charts
Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors
Phase 1/2 Completed
76 enrolled 25 charts
Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma
Phase 2 Completed
244 enrolled 15 charts
Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric Solid Tumors, Including Central Nervous System Tumors
Phase 1/2 Completed
64 enrolled 29 charts
Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme
Phase 3 Completed
562 enrolled 11 charts
Study of Irinotecan and Bevacizumab With Temozolomide in Refractory/Relapsed Central Nervous System (CNS) Tumors
Phase 1 Completed
26 enrolled 16 charts
Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma
Phase 2 Completed
14 enrolled 11 charts
Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV Glioma
Phase 1/2 Completed
12 enrolled 11 charts
A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects
Phase 2 Completed
361 enrolled 11 charts
Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas
Phase 2 Completed
118 enrolled 8 charts
RTOG 0913
Phase 1/2 Completed
279 enrolled 14 charts
O6-Benzylguanine and Temozolomide in Treating Young Patients With Recurrent or Progressive Gliomas or Brain Stem Tumors
Phase 2 Completed
41 enrolled 9 charts
Proton Beam Radiation Therapy in Treating Young Patients Who Have Undergone Biopsy or Surgery for Medulloblastoma or Pineoblastoma
Phase NA Completed
59 enrolled 26 charts
Temozolomide Alone or in Combination With Thalidomide and/or Isotretinoin and/or Celecoxib in Treating Patients Who Have Undergone Radiation Therapy for Glioblastoma Multiforme
Phase 2 Completed
178 enrolled 23 charts
SCUSF1202
Phase NA Completed
187 enrolled 5 charts
A Study of Ramucirumab (LY3009806) in Children With Refractory Solid Tumors
Phase 1 Completed
29 enrolled 12 charts
Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor
Phase 2 Completed
112 enrolled 16 charts
Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors
Phase 2 Completed
108 enrolled 14 charts
GP96 Heat Shock Protein-Peptide Complex Vaccine in Treating Patients With Recurrent or Progressive Glioma
Phase 1/2 Completed
96 enrolled 19 charts
Talazoparib and Temozolomide in Treating Younger Patients With Refractory or Recurrent Malignancies
Phase 1/2 Completed
40 enrolled 32 charts
HeatShock
Phase 2 Completed
70 enrolled 12 charts
Imaging Brain Tumors With FACBC and Methionine
Phase NA Completed
30 enrolled 7 charts
Bevacizumab, Temozolomide, and External Beam Radiation Therapy as First-Line Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma
Phase 2 Completed
70 enrolled 18 charts
Bortezomib, Temozolomide, and Regional Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma
Phase 2 Completed
24 enrolled 10 charts
Intrathecal Radioimmunotherapy, Radiation Therapy, and Chemotherapy After Surgery in Treating Patients With Medulloblastoma
Phase NA Completed
6 enrolled 8 charts
Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma
Phase 1/2 Completed
122 enrolled 11 charts
Dasatinib or Placebo, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Phase 1/2 Completed
217 enrolled 12 charts
Bevacizumab in Treating Patients With Recurrent or Progressive Glioma
Phase 2 Completed
55 enrolled 10 charts
Radiation Therapy Combined With Chemotherapy in Treating Patients With Anaplastic Astrocytoma or Mixed Gliomas
Phase 3 Completed
230 enrolled 14 charts
Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma
Phase 2 Completed
378 enrolled 16 charts