Clinical Trials

Ependymoma, Glioblastoma, Central Nervous System Neoplasms

NCT03270059 2026-02-27

Gadolinium and Ferumoxytol MRI in Diagnosing Patients With Abnormalities in the Central Nervous System

Phase 2 Recruiting

150 enrolled

Phase 2 Active not recruiting

Brain Neoplasms, Cranial Nerve Diseases, Central Nervous System Neoplasms

NCT03155620 2026-02-10

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

1,376 enrolled

CNSGastrointestinalGenitourinaryLymphoidMyeloidSarcoma

Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Lymphoma, Non-Hodgkin, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Xanthogranuloma, Juvenile, Central Nervous System Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor, Histiocytic Sarcoma

NCT03213704 2025-12-03

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

Phase 2 Active not recruiting

9 enrolled 12 charts

CNSGastrointestinalGenitourinaryLymphoidMyeloidSarcoma

Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Lymphoma, Non-Hodgkin, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT05720624 2025-10-22

Pharmacodynamic Analyses of Metabolic Agents Following Brain Radiation

Phase 1 Withdrawn

CNSGastrointestinalGenitourinaryLymphoidMyeloidSarcoma

Central Nervous System Neoplasms

NCT03213678 2025-01-27

Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)

Phase 2 Completed

18 enrolled 12 charts

Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Lymphoma, Non-Hodgkin, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT04276194 2024-03-21

Vertebral Body Sparing Craniospinal Irradiation for Pediatric Patients With Cancer of the Central Nervous System

10 enrolled

Central Nervous System Neoplasms

NCT03565367 2023-12-21

Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Detecting Lactate and Bicarbonate in Participants With Central Nervous System Tumors

Phase 1 Completed

9 enrolled 6 charts

Central Nervous System Neoplasms

NCT00633958 2021-10-20

FLT

Phase 1 Terminated

2 enrolled

Disease, Central Nervous System Neoplasms

NCT00597246 2020-12-17

Imaging Brain Tumors With FACBC and Methionine

30 enrolled 7 charts

Brain Neoplasms, Central Nervous System Neoplasms

NCT00276770 2019-02-27

Positron Emission Tomography Using Fluorothymidine F 18 in Finding Recurrent Disease in Patients With Gliomas

12 enrolled

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00274755 2014-05-20

Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging in Evaluating Patients Who Are Undergoing Treatment for Gliomas

Phase 2 Completed

250 enrolled

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Glioma, Subependymal, Gliosarcoma

NCT00005084 2013-12-18

Magnetic Resonance Imaging in Treating Children With Progressive Low-Grade Astrocytoma

Phase 2 Unknown

24 enrolled

Astrocytoma, Central Nervous System Neoplasms

NCT00087815 2013-12-18

Hyperbaric Oxygen Therapy in Treating Patients With Radiation Necrosis of the Brain

Phase NA Unknown

30 enrolled

Brain Neoplasms, Radiation Injuries, Central Nervous System Neoplasms

NCT00258453 2013-08-02

Observation of Young Patients Who Are Undergoing Surgery for Craniopharyngioma

120 enrolled

Body Weight Changes, Postoperative Complications, Central Nervous System Neoplasms

NCT00003410 2013-06-26

Motexafin Gadolinium With MRI-Guided Surgery in Treating Patients With High-Grade Gliomas

Phase 1 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00005082 2013-01-08

Magnetic Resonance Imaging in Determining Extent of Cancer in Patients With Newly Diagnosed Glioma

1 enrolled

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT00005083 2012-10-04

Functional Magnetic Resonance Imaging and 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Treating Patients With Newly Diagnosed Brain Tumors

Phase 2 Withdrawn

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT00005790 2012-06-11

Perfusion Magnetic Resonance Imaging in Measuring the Growth of Blood Vessels in Newly Diagnosed Brain Tumors

Phase NA Withdrawn