Clinical Trials Browser

Completed × Central Nervous System Neoplasms × Temozolomide × Clear all

NCT02975882 2025-01-14

Nanoparticle Albumin-Bound Rapamycin, Temozolomide, and Irinotecan Hydrochloride in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors

Phase 1 Completed

33 enrolled 15 charts

Central Nervous System Neoplasms

NCT03323034 2024-10-22

Pevonedistat, Irinotecan, and Temozolomide in Treating Patients With Recurrent or Refractory Solid Tumors or Lymphoma

Phase 1 Completed

30 enrolled 19 charts

Lymphoma, Central Nervous System Neoplasms

NCT00114140 2024-07-08

Temozolomide and Radiation Therapy in Treating Patients With Gliomas

Phase 2 Completed

136 enrolled 9 charts

Astrocytoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00482677 2023-08-22

Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 3 Completed

562 enrolled 11 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00387400 2023-08-04

Temozolomide + Everolimus in Newly Diagnosed, Recurrent, or Progressive Malignant Glioblastoma Multiforme

Phase 1 Completed

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00876993 2023-07-03

Study of Irinotecan and Bevacizumab With Temozolomide in Refractory/Relapsed Central Nervous System (CNS) Tumors

Phase 1 Completed

26 enrolled 16 charts

Central Nervous System Neoplasms

NCT00100802 2023-02-15

Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas

Phase 2 Completed

118 enrolled 8 charts

Astrocytoma, Glioblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Gliosarcoma

NCT00275002 2022-02-11

O6-Benzylguanine and Temozolomide in Treating Young Patients With Recurrent or Progressive Gliomas or Brain Stem Tumors

Phase 2 Completed

41 enrolled 9 charts

Central Nervous System Neoplasms

NCT00112502 2021-10-18

Temozolomide Alone or in Combination With Thalidomide and/or Isotretinoin and/or Celecoxib in Treating Patients Who Have Undergone Radiation Therapy for Glioblastoma Multiforme

Phase 2 Completed

178 enrolled 23 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00049361 2021-09-09

Radiation Therapy Plus Thalidomide and Temozolomide in Treating Patients With Newly Diagnosed Brain Metastases

Phase 2 Completed

Brain Neoplasms, Central Nervous System Neoplasms

NCT01217437 2021-07-23

Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors

Phase 2 Completed

108 enrolled 14 charts

Medulloblastoma, Pinealoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Neuroectodermal Tumors, Primitive

NCT02116777 2021-03-26

Talazoparib and Temozolomide in Treating Younger Patients With Refractory or Recurrent Malignancies

Phase 1/2 Completed

40 enrolled 32 charts

Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral

NCT00905060 2021-03-24

HeatShock

Phase 2 Completed

70 enrolled 12 charts

Central Nervous System Neoplasms

NCT01013285 2020-09-21

Bevacizumab, Temozolomide, and External Beam Radiation Therapy as First-Line Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

Phase 2 Completed

70 enrolled 18 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00553150 2020-02-13

Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Phase 1/2 Completed

122 enrolled 11 charts

Astrocytoma, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00869401 2020-02-13

Dasatinib or Placebo, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 1/2 Completed

217 enrolled 12 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00004259 2019-09-12

Radiation Therapy Combined With Chemotherapy in Treating Patients With Anaplastic Astrocytoma or Mixed Gliomas

Phase 3 Completed

230 enrolled 14 charts

Astrocytoma, Glioma, Central Nervous System Neoplasms

NCT00486603 2019-07-10

Hydroxychloroquine, Radiation, and Temozolomide Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 1/2 Completed

92 enrolled 18 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01480050 2019-05-22

Mibefradil Dihydrochloride and Temozolomide in Treating Patients With Recurrent Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT01164189 2019-02-28

TAVAREC

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00313729 2019-02-07

Temozolomide in Treating Patients With Low-Grade Glioma

Phase 2 Completed

120 enrolled 8 charts

Astrocytoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00400816 2018-09-18

Temozolomide in Treating Patients With Newly Diagnosed Anaplastic Oligodendroglioma or Mixed Oligoastrocytoma

Phase 2 Completed

Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT01019434 2018-07-09

Radiation Therapy and Temsirolimus or Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Phase 2 Completed

Glioblastoma, Central Nervous System Neoplasms

NCT00003176 2018-06-27

Temozolomide and Carmustine in Treating Patients With Anaplastic Glioma

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00006025 2018-06-27

Temozolomide Plus Irinotecan in Treating Patients With Recurrent Malignant Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00027625 2018-06-27

Gefitinib Plus Temozolomide in Treating Patients With Malignant Primary Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00770471 2018-06-27

ABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 1 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00006358 2018-06-26

Temozolomide Plus Thalidomide in Treating Patients With Recurrent or Progressive Brain Tumor

Phase 2 Completed

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00077207 2018-05-16

Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade Glioma

Phase NA Completed

66 enrolled 13 charts

Brain Neoplasms, Oligodendroglioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT00974987 2018-04-25

Boron Neutron Capture Therapy, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 2 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00547131 2018-04-17

Temozolomide in Treating Patients With Primary Brain Tumors or Metastatic Brain Tumors

Phase 1 Completed

Brain Neoplasms, Neoplasm Metastasis, Central Nervous System Neoplasms

NCT00068250 2018-02-07

Combination Chemotherapy, Monoclonal Antibody, and Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma

Phase 1/2 Completed

60 enrolled 10 charts

Lymphoma, Central Nervous System Neoplasms

NCT01390571 2018-02-05

Olaparib and Temozolomide in Treating Patients With Relapsed Glioblastoma

Phase 1 Completed

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00619112 2018-01-31

Temozolomide in Treating Patients With Recurrent High-Grade Glioma

Phase 2 Completed

60 enrolled 9 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00086879 2017-07-27

Erlotinib Compared With Temozolomide or Carmustine in Treating Patients With Recurrent Glioblastoma Multiforme

Phase 2 Completed

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00047294 2017-07-11

Temozolomide, Thalidomide, and Celecoxib Following Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 2 Completed

Glioblastoma, Glioma, Central Nervous System Neoplasms, Gliosarcoma

NCT01026493 2017-07-02

Veliparib and Temozolomide in Treating Patients With Recurrent Glioblastoma

Phase 1/2 Completed

257 enrolled 16 charts

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00182819 2016-10-12

Radiation Therapy or Temozolomide in Treating Patients With Gliomas

Phase 3 Completed

Astrocytoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00498927 2016-02-29

Temozolomide in Treating Patients With Recurrent Glioblastoma Multiforme or Other Malignant Glioma

Phase 2 Completed

47 enrolled 7 charts

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Glioma, Subependymal, Gliosarcoma

NCT01222221 2015-10-14

Vaccine Therapy, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 1 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00020150 2015-04-29

Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors

Phase 1 Completed

CNSGastrointestinalGenitourinaryGynecologicSarcoma

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

NCT00098865 2014-10-07

Thalidomide and Temozolomide in Relapsed or Progressive CNS Disease or Neuroblastoma

Phase 2 Completed

15 enrolled 9 charts

Neuroblastoma, Central Nervous System Neoplasms

NCT00005951 2014-08-22

Irinotecan Plus Temozolomide in Treating Patients With Recurrent Primary Malignant Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003466 2014-07-09

Temozolomide in Treating Patients With Progressive Low-Grade Glioma

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Glioma, Subependymal, Optic Nerve Glioma

NCT00028795 2014-02-21

Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Glioblastoma Multiforme, Gliosarcoma, or Diffuse Intrinsic Pontine Glioma

Phase 2 Completed

Astrocytoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT00006024 2014-02-13

Temozolomide Plus Lomustine Followed by Radiation Therapy in Treating Patients With High-Grade Malignant Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Central Nervous System Neoplasms

NCT00099125 2014-01-24

Radiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 2 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00253487 2014-01-06

Combination Chemotherapy and Radiation Therapy in Treating Younger Patients Who Are Undergoing an Autologous Stem Cell Transplant for Newly Diagnosed Gliomas

Phase NA Completed

Astrocytoma, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00052455 2013-12-18

Temozolomide Compared to Procarbazine, Lomustine, and Vincristine in Treating Patients With Recurrent Malignant Glioma

Phase 3 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003464 2013-06-20

Temozolomide in Treating Adults With Newly Diagnosed Primary Malignant Glioblastoma Multiforme

Phase 2 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma