Clinical Trials

35 enrolled 13 charts

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT04743310 2025-06-13

Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System

50 enrolled

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasms, Germ Cell and Embryonal, Neuroma, Acoustic, Pinealoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT04479514 2025-05-01

Preventative Skin Care for Children Undergoing Targeted CNS Tumor Therapy

14 enrolled 6 charts

Dermatitis, Neoplasms, Central Nervous System Neoplasms

NCT03213691 2025-02-05

Selumetinib Sulfate in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

21 enrolled 11 charts

CNSLymphoid

Lymphoma, Non-Hodgkin, Neuroblastoma, Central Nervous System Neoplasms

NCT03213665 2025-01-27

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)

CNSGastrointestinalGenitourinaryLymphoidMyeloidSarcoma

20 enrolled 12 charts

Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Hodgkin Disease, Lymphoma, Non-Hodgkin, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT03213678 2025-01-27

Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)

CNSGastrointestinalGenitourinaryLymphoidMyeloidSarcoma

18 enrolled 12 charts

Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Lymphoma, Non-Hodgkin, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT03220035 2025-01-27

Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)

CNSGastrointestinalGenitourinaryLymphoidMyeloidSarcoma

4 enrolled 12 charts

Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Lymphoma, Non-Hodgkin, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT03233204 2024-12-11

Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)

CNSGastrointestinalGenitourinaryLymphoidMyeloidSarcoma

6 enrolled 12 charts

Familial ependymoma, Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Lymphoma, Non-Hodgkin, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT00114140 2024-07-08

Temozolomide and Radiation Therapy in Treating Patients With Gliomas

136 enrolled 9 charts

Astrocytoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT03257631 2024-04-16

A Study of Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors

53 enrolled 18 charts

Brain Neoplasms, Ependymoma, Glioma, Medulloblastoma, Central Nervous System Neoplasms

NCT00445965 2024-04-04

Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer

CNSDermatologicGynecologicOther solid neoplasmSarcomaThoracic

78 enrolled 11 charts

Familial ependymoma, Uveal Melanoma, Astrocytoma, Brain Neoplasms, Chondrosarcoma, Ependymoma, Glioblastoma, Glioma, Lung Neoplasms, Medulloblastoma, Melanoma, Neoplasm Metastasis, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Glioma, Subependymal, Gliosarcoma, Rhabdoid Tumor, Optic Nerve Glioma, Small Cell Lung Carcinoma, Desmoplastic Small Round Cell Tumor

NCT03012620 2024-02-28

AcSé

CNSEndocrineGynecologicHead & NeckLymphoidSarcoma

334 enrolled

Neoplasms, Germ Cell and Embryonal, Ovarian Neoplasms, Sarcoma, Thyroid Neoplasms, Central Nervous System Neoplasms, Carcinoma, Neuroendocrine, Lymphoma, Extranodal NK-T-Cell

NCT00002965 2023-12-22

Interferon Alfa in Treating Patients With Recurrent Unresectable Meningiomas and Malignant Meningiomas

16 enrolled

Brain Neoplasms, Central Nervous System Neoplasms

NCT00588523 2023-10-27

Intensive Chemotherapy and Autotransplantation for Patients With Newly Diagnosed Anaplastic Oligodendroglioma

60 enrolled 9 charts

Central Nervous System Neoplasms

NCT00895622 2023-09-08

Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma

244 enrolled 15 charts

Brain Neoplasms, Meningioma, Central Nervous System Neoplasms

NCT01290692 2023-07-03

Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma

14 enrolled 11 charts

Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Glioblastoma, Glioma, Neoplasms, Nervous System Diseases, Nervous System Neoplasms, Central Nervous System Neoplasms

NCT00003309 2023-06-22

Combination Chemotherapy Plus Radiation Therapy in Treating Adult Patients With Brain Cancer

33 enrolled

Ependymoma, Medulloblastoma, Central Nervous System Neoplasms

NCT00028678 2023-06-18

Dalteparin and Radiation Therapy in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme

45 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00082797 2023-06-15

High-Dose Methotrexate and Leucovorin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

36 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00187226 2023-05-31

A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects

361 enrolled 11 charts

Brain Neoplasms, Central Nervous System Neoplasms

NCT00100802 2023-02-15

Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas

118 enrolled 8 charts

Astrocytoma, Glioblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Gliosarcoma

NCT00275002 2022-02-11

O6-Benzylguanine and Temozolomide in Treating Young Patients With Recurrent or Progressive Gliomas or Brain Stem Tumors

41 enrolled 9 charts

Central Nervous System Neoplasms

NCT00112502 2021-10-18

Temozolomide Alone or in Combination With Thalidomide and/or Isotretinoin and/or Celecoxib in Treating Patients Who Have Undergone Radiation Therapy for Glioblastoma Multiforme

178 enrolled 23 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00752323 2021-09-17

Imaging Procedure Using ALA in Finding Residual Tumor in Grade IV Malignant Astrocytoma

73 enrolled

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00049361 2021-09-09

Radiation Therapy Plus Thalidomide and Temozolomide in Treating Patients With Newly Diagnosed Brain Metastases

Brain Neoplasms, Central Nervous System Neoplasms

NCT00070161 2021-09-09

Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor

68 enrolled

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Oligodendroglioma, Pinealoma, Radiation Injuries, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT00079092 2021-09-09

Thalidomide and Procarbazine in Treating Patients With Recurrent or Progressive Malignant Glioma

18 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT01381718 2021-08-13

Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor

112 enrolled 16 charts

Fatigue, Central Nervous System Neoplasms, Neurotoxicity Syndromes

NCT01217437 2021-07-23

Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors

108 enrolled 14 charts

Medulloblastoma, Pinealoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Neuroectodermal Tumors, Primitive

NCT00905060 2021-03-24

HeatShock

70 enrolled 12 charts

Central Nervous System Neoplasms

NCT00006119 2021-02-21

Hydroxyurea in Treating Patients With Recurrent and/or Unresectable Meningioma

Brain Neoplasms, Meningioma, Central Nervous System Neoplasms

NCT00006386 2020-10-22

Radiation Therapy Followed by Carmustine in Treating Patients Who Have Supratentorial Glioblastoma Multiforme

80 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00006388 2020-10-22

Radiation Therapy and Tamoxifen in Treating Adults With Newly Diagnosed Supratentorial Glioblastoma Multiforme

77 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01013285 2020-09-21

Bevacizumab, Temozolomide, and External Beam Radiation Therapy as First-Line Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

70 enrolled 18 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00998010 2020-08-28

Bortezomib, Temozolomide, and Regional Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

24 enrolled 10 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00179803 2020-08-05

Stem Cell Transplant for High Risk Central Nervous System (CNS) Tumors

24 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Pinealoma, Supratentorial Neoplasms, Central Nervous System Neoplasms, Rhabdoid Tumor

NCT00003372 2020-04-08

Topotecan in Treating Patients With Recurrent Brain Tumors

17 enrolled

Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00036660 2020-04-06

SarCNU in Treating Patients With Recurrent Malignant Glioma

10 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00337207 2020-02-07

Bevacizumab in Treating Patients With Recurrent or Progressive Glioma

55 enrolled 10 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00027846 2019-08-07

Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma

378 enrolled 16 charts

Brain Neoplasms, Central Nervous System Neoplasms

NCT00238264 2019-08-07

Radiation Therapy in Treating Young Patients With Gliomas

92 enrolled 12 charts

Astrocytoma, Brain Neoplasms, Oligodendroglioma, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT01164189 2019-02-28

TAVAREC

155 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00313729 2019-02-07

Temozolomide in Treating Patients With Low-Grade Glioma

120 enrolled 8 charts

Astrocytoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00348790 2018-10-26

Vatalanib in Treating Patients With Recurrent or Progressive Meningioma

25 enrolled 10 charts

Hemangiopericytoma, Malignant, Brain Neoplasms, Meningioma, Sarcoma, Central Nervous System Neoplasms

NCT00720356 2018-10-26

Bevacizumab and Erlotinib After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

115 enrolled 11 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00400816 2018-09-18

Temozolomide in Treating Patients With Newly Diagnosed Anaplastic Oligodendroglioma or Mixed Oligoastrocytoma

29 enrolled

Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00058123 2018-08-21

Poly-ICLC in Treating Patients With Recurrent or Progressive Anaplastic Glioma

55 enrolled 8 charts

Astrocytoma, Brain Neoplasms, Ependymoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT01019434 2018-07-09

Radiation Therapy and Temsirolimus or Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

111 enrolled

Glioblastoma, Central Nervous System Neoplasms

NCT00003176 2018-06-27

Temozolomide and Carmustine in Treating Patients With Anaplastic Glioma

82 enrolled