Clinical Trials

15 enrolled

Carcinoma, Hepatocellular, Pancreatic Neoplasms, Cholangiocarcinoma

NCT06282575 2026-02-24

Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

Phase 3 Recruiting

286 enrolled

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT07260175 2026-02-23

adIVO

40 enrolled

Cholangiocarcinoma

NCT05876754 2026-02-19

ProvIDHe

Phase 3 Recruiting

220 enrolled

Cholangiocarcinoma

NCT07023731 2026-02-19

A Study to Evaluate ARV-806 in Adults With Advanced Cancer That Has the KRAS G12D Mutation

DermatologicGastrointestinalGynecologicHead & NeckThoracic

159 enrolled

Adenocarcinoma Of Esophagus, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Gallbladder Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT07146646 2026-02-19

Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer

27 enrolled

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT07334119 2026-02-19

Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of MT-304 in Adults With Advanced HER2-Expressing Solid Tumors

BreastGastrointestinalGenitourinaryGynecologicThoracic

Adenocarcinoma Of Esophagus, Carcinoma, Ovarian Epithelial, Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT03445585 2026-02-17

Biobank for Cholestatic Liver Diseases.

9,150 enrolled

Liver Cirrhosis, Biliary, Liver Neoplasms, Cholangitis, Sclerosing, Cholangiocarcinoma

NCT04753996 2026-02-17

Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC Patients

300 enrolled

Cholangitis, Sclerosing, Cholangiocarcinoma

NCT07223307 2026-02-09

REGULUS: MRI-guided Adaptive SABR for Liver Cancers

62 enrolled

Liver Neoplasms, Cholangiocarcinoma

NCT01915225 2026-02-05

Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer

1,800 enrolled

Bile Duct Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT07201519 2026-02-04

Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy

80 enrolled

Cholangiocarcinoma

NCT06313203 2026-02-02

TOMCAT

39 enrolled

Cholangiocarcinoma

NCT05150691 2026-01-28

A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

BreastGastrointestinalGynecologicThoracic

796 enrolled

Bile Duct Neoplasms, Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Liver Neoplasms, Neoplasm Metastasis, Neoplasms, Recurrence, Stomach Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT04421820 2026-01-27

BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours

220 enrolled

Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT06048133 2026-01-23

Study of Gemcitabine, Cisplatin, AB680 and AB122 During First Line Treatment of Advanced Biliary Tract Cancers (QUIC)

33 enrolled

Bile Duct Neoplasms, Cholangiocarcinoma

NCT07265674 2026-01-23

Beacon-BTC

Phase 3 Recruiting

480 enrolled

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT05874414 2026-01-22

Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma

74 enrolled

Bile Duct Neoplasms, Cholangiocarcinoma

NCT07359586 2026-01-22

Laryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia

GastrointestinalHead & NeckThoracic

1,200 enrolled

Carcinoma, Hepatocellular, Hoarseness, Lung Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thyroid Neoplasms, Cholangiocarcinoma

NCT04145141 2026-01-21

National Translational Science Network of Precision-based Immunotherapy for Primary Liver Cancer

500 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms, Cholangiocarcinoma

NCT06302621 2026-01-15

Pemigatinib + Afatinib in Advanced Refractory Solid Tumors

70 enrolled

Neoplasm Metastasis, Cholangiocarcinoma

NCT07235007 2026-01-13

BRAVE

120 enrolled

Biliary Tract Neoplasms, Cholangiocarcinoma

NCT07337850 2026-01-13

FAPi-2

Cirrhosis, Familial, with Pulmonary Hypertension, Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT06399757 2026-01-07

A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

BreastGastrointestinalGenitourinaryGynecologic

100 enrolled

Adenocarcinoma, Mucinous, Ovarian Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma, Triple Negative Breast Neoplasms

NCT05727176 2025-12-29

FOENIX-CCA4

120 enrolled

Cholangiocarcinoma

NCT07169734 2025-12-18

A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors

GastrointestinalGenitourinary

180 enrolled

Carcinoma, Transitional Cell, Colorectal Neoplasms, Cholangiocarcinoma

NCT07291063 2025-12-18

Anti-PD-1/PD-L1 Antibodies Plus Gemcitabine and Cisplatin for Advanced CCA

50 enrolled

Cholangiocarcinoma

NCT07291947 2025-12-18

PULSAR Combined With Immunotherapy and Chemotherapy

Cholangiocarcinoma

NCT06416397 2025-12-16

PROTEOBILE

200 enrolled

Disease, Neoplasms, Cholangiocarcinoma

NCT03823144 2025-12-11

Intravital Microscopy in Human Solid Tumors

BreastCNSGastrointestinalSarcoma

85 enrolled

Brain Neoplasms, Breast Neoplasms, Carcinoma, Hepatocellular, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT06546969 2025-12-10

Chemoimmunotherapy Combined With Hyperthermia and Spatially-Fractionated Radiotherapy in Advanced Biliary Tract Cancer

15 enrolled

Biliary Tract Neoplasms, Cholangiocarcinoma

NCT06735560 2025-12-08

ELEGANCE

EndocrineGastrointestinalNET

Cirrhosis, Familial, with Pulmonary Hypertension, Carcinoma, Hepatocellular, Cholangiocarcinoma, Neuroendocrine Tumors

NCT07263217 2025-12-04

Mechanistic Study on the Protective and Regenerative Effects of Spirulina in Hepatectomy-Related Liver Injury

30 enrolled

Cholangiocarcinoma

NCT06440993 2025-12-01

Durvalumab + Intraductal Radiofrequency Ablation (ID-RFA) in Extrahepatic Cholangiocarcinoma

42 enrolled

Cholangiocarcinoma

NCT06925516 2025-11-28

ACADEMY

38 enrolled

Cirrhosis, Familial, with Pulmonary Hypertension, Cholangiocarcinoma

NCT04891289 2025-11-24

Gemcitabine and Oxaliplatin Chemotherapy With or Without a Floxuridine and Dexamethasone Pump in People With Cholangiocarcinoma That Cannot Be Removed With Surgery

164 enrolled

Cholangiocarcinoma

NCT07106827 2025-11-24

A Study of GV20-0251 in Advanced or Refractory Solid Tumors

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

10 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Melanoma, Testicular Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT06529718 2025-11-17

SEVILLA

72 enrolled

Biliary Tract Neoplasms, Cholangiocarcinoma

NCT05732831 2025-11-14

Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors

GastrointestinalOther solid neoplasmSarcomaThoracic

225 enrolled

Mesothelioma, Sarcoma, Cholangiocarcinoma, Neurofibrosarcoma

NCT06503146 2025-11-12

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection