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Chordoma × Afatinib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Conditions

Carcinoma, Non-Small-Cell Lung 58 Neoplasms 21 Squamous Cell Carcinoma of Head and Neck 12 Breast Neoplasms 11 Lung Neoplasms 10 Head and Neck Neoplasms 10 Neoplasm Metastasis 8 Carcinoma, Squamous Cell 6 Esophageal Squamous Cell Carcinoma 5 Stomach Neoplasms 4 Pancreatic Neoplasms 4 Prostatic Neoplasms 3 Glioblastoma 3 Esophageal Neoplasms 3 Colorectal Neoplasms 3 Adenocarcinoma 3 Solid Tumors 2 Non-small-cell Lung Cancer With Somatic EGFR Mutations 2 NSCLC 2 Multiple Myeloma 2 Brain Neoplasms 2 Adenocarcinoma of Lung 2 Urologic Neoplasms 1 Urinary Bladder Neoplasms 1 Urethral Neoplasms 1 Ureteral Neoplasms 1 Triple Negative Breast Neoplasms 1 Thrombocytosis 1 Thoracic Neoplasms 1 Squamous Non-small Cell Lung Cancer 1

Interventions

Nivolumab 6 Imatinib Mesylate 4 Ipilimumab 3 palbociclib 2 Specimen Handling 2 Radiosurgery 2 Protons 2 Proton Therapy 2 Pemetrexed 2 Magnetic Resonance Spectroscopy 2 Cyclophosphamide 2 Cetuximab 2 tazemetostat 1 spartalizumab 1 relatlimab 1 pembrolizumab 1 camrelizumab 1 avelumab 1 atezolizumab 1 apatinib 1 Zoledronic Acid 1 X-Rays 1 Tiragolumab 1 Thiotepa 1 Surveys and Questionnaires 1 Radiotherapy, Intensity-Modulated 1 Radiotherapy 1 Radiation 1 Photochemotherapy 1 Phantoms, Imaging 1

Date Range

30 days 90 days 1 year All

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Has results Has announcements

NCT03083678 2025-02-13

Afatinib in Locally Advanced and Metastatic Chordoma

Leiden University Medical Center

Phase 2 Completed

Chordoma

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