Clinical Trials

Chordoma

NCT05861245 2026-01-23

Hypofractionated Protontherapy in Chordomas and Chondrosarcomas of the Skull Base

Phase NA Recruiting

20 enrolled

Chondrosarcoma, Chordoma

NCT06957327 2026-01-21

A Study of ERAS-601 in People With Chordoma

Phase 1/2 Recruiting

46 enrolled

Phase 1 Active not recruiting

Chordoma

NCT02989636 2026-01-06

Nivolumab With or Without Stereotactic Radiosurgery in Treating Patients With Recurrent, Advanced, or Metastatic Chordoma

21 enrolled

Phase 2 Active not recruiting

Chordoma

NCT04416568 2025-12-17

Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers

45 enrolled

Phase 2 Active not recruiting

Chordoma, Sarcoma, Rhabdoid Tumor

NCT00496119 2025-12-16

Proton Beam Therapy for Chordoma Patients

19 enrolled

Chordoma

NCT01449149 2025-12-05

Proton Radiation for Chordomas and Chondrosarcomas

54 enrolled 11 charts

Chondrosarcoma, Chordoma

NCT05407441 2025-10-03

Tazemetostat+Nivo/Ipi in INI1-Neg/SMARCA4-Def Tumors

Phase 1/2 Recruiting

49 enrolled

DermatologicGastrointestinalGenitourinarySarcomaThoracic

Chordoma, Sarcoma, Rhabdoid Tumor

NCT03190174 2025-02-17

Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers

Phase 1/2 Completed

34 enrolled 14 charts

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Chordoma, Carcinoma, Hepatocellular, Melanoma, Sarcoma, Sarcoma, Ewing, Colorectal Neoplasms, Desmoid Tumors, Perivascular Epithelioid Cell Neoplasms

NCT03083678 2025-02-13

Afatinib in Locally Advanced and Metastatic Chordoma

43 enrolled

Chordoma

NCT06794645 2025-01-27

Pembrolizumab and Pemetrexed for Progressive Chordoma

Phase 2 Recruiting

21 enrolled

Chordoma

NCT06029218 2024-09-25

P1V2

Phase NA Recruiting

106 enrolled

Chondrosarcoma, Chordoma, Sarcoma, Ewing, Osteosarcoma

NCT03623854 2024-04-16

Nivolumab and Relatlimab in Treating Participants With Advanced Chordoma

10 enrolled

Chordoma

NCT03242382 2024-01-23

PalboSarc

40 enrolled

Chordoma, Sarcoma, Osteosarcoma

NCT01811394 2023-12-06

ISAC

100 enrolled

Chordoma

NCT06140732 2023-11-20

Apatinib Combined With Camrelizumab in Treating Participants With Advanced Chordoma

30 enrolled

Chordoma

NCT05707767 2023-07-19

A Prospective Study of Surgical Treatment Strategies for Chordoma

Phase NA Unknown

100 enrolled

Chordoma

NCT03110744 2023-03-27

NCT-PMO-1601

43 enrolled

Chordoma

NCT03955042 2023-03-07

Pemetrexed for the Treatment of Chordoma

Phase 1 Completed

15 enrolled

Chordoma

NCT02520128 2020-12-02

IMRiS

191 enrolled

Bone Neoplasms, Chordoma, Sarcoma, Sarcoma, Ewing

NCT01347307 2020-06-18

Stereotactic Body Radiotherapy for Spine Tumors

38 enrolled 11 charts

CNSEndocrineSarcoma

Arteriovenous Malformations, Chordoma, Meningioma, Neurilemmoma, Neurofibroma, Paraganglioma

NCT01966809 2019-08-20

Photodynamic Therapy (PDT) For Recurrent High Grade Gliomas

Phase 2 Terminated

1 enrolled 5 charts

CNSEndocrineSarcoma

Astrocytoma, Brain Neoplasms, Chordoma, Craniopharyngioma, Glioblastoma, Glioma, Meningioma, Neoplasms, Germ Cell and Embryonal, Oligodendroglioma, Pituitary Neoplasms, Germinoma, Optic Nerve Glioma

NCT04042597 2019-08-05

CSSG-03

60 enrolled

Chordoma

NCT01682746 2019-02-25

Photodynamic Therapy (PDT) for Recurrent Pediatric Brain Tumors

Phase 1 Completed

5 enrolled

CNSEndocrineSarcoma

Astrocytoma, Brain Neoplasms, Chordoma, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasms, Germ Cell and Embryonal, Oligodendroglioma, Pituitary Neoplasms, Germinoma, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Optic Nerve Glioma

NCT00464620 2018-11-23

Trial of Dasatinib in Advanced Sarcomas

CNSGastrointestinalGenitourinaryGynecologicOther solid neoplasmSarcoma

366 enrolled 16 charts

GastrointestinalSarcoma

Chondrosarcoma, Chordoma, Hemangiopericytoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Giant Cell Tumor of Bone, Sarcoma, Alveolar Soft Part, Neurofibrosarcoma, Gastrointestinal Stromal Tumors, Solitary Fibrous Tumors

NCT00003926 2017-11-29

Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors

Phase 1 Terminated

13 enrolled

Ovarian Germ Cell Cancer, Astrocytoma, Brain Neoplasms, Chordoma, Ependymoma, Glioma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Ovarian Neoplasms, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Neuroectodermal Tumors, Hepatoblastoma, Desmoplastic Small Round Cell Tumor

NCT00592748 2017-06-16

Charged Particle RT for Chordomas and Chondrosarcomas of the Base of Skull or Cervical Spine

Phase 1/2 Completed

381 enrolled

Chondrosarcoma, Chordoma

NCT00713037 2017-02-03

Hypoxia-positron Emission Tomography (PET) and Intensity Modulated Proton Therapy (IMPT) Dose Painting in Patients With Chordomas

20 enrolled

Chordoma

NCT01175109 2012-12-27

Study of Imatinib, a Platelet-derived Growth Factor Receptor Inhibitor, and LBH589, a Histone Deacetylase Inhibitor, in the Treatment of Newly Diagnosed and Recurrent Chordoma

Phase 1 Unknown

36 enrolled

Chordoma

NCT01182779 2010-08-17

HIT-1

Phase 3 Unknown

319 enrolled