Clinical Trials

240 enrolled 14 charts

Colonic Neoplasms, Rectal Neoplasms

NCT04505553 2026-01-21

Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer

EndocrineGastrointestinalNET

78 enrolled 14 charts

Gastro-enteropancreatic neuroendocrine tumor, Anus Neoplasms, Appendiceal Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Carcinoma, Hepatocellular, Adenoma, Islet Cell, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT05169437 2025-10-29

PAVO

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

22 enrolled 17 charts

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms, Urologic Neoplasms, Endometrial Neoplasms

NCT05678257 2025-09-12

A Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer

180 enrolled 16 charts

Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT00766142 2025-08-29

COCHISE

GastrointestinalGynecologic

18 enrolled 9 charts

Colonic Neoplasms, Peritoneal Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT03442569 2025-07-01

PhII Trial Panitumumab, Nivolumab, Ipilimumab in Kras/Nras/BRAF Wild-type MSS Refractory mCRC

56 enrolled 13 charts

Colonic Neoplasms

NCT02368886 2025-06-18

Lower or Standard Dose Regorafenib in Treating Patients With Refractory Metastatic Colorectal Cancer

123 enrolled 21 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT04625803 2025-06-17

Neoadjuvant Therapy for Locally Advanced Colon Cancer

64 enrolled 11 charts

Colonic Neoplasms

NCT03642067 2025-06-15

Study of Nivolumab and Relatlimab in Patients With Microsatellite Stable (MSS) Advanced Colorectal Cancer

59 enrolled 11 charts

Colonic Neoplasms, Rectal Neoplasms, Spinocerebellar Degenerations, Colorectal Neoplasms

NCT02138617 2025-05-18

Genotype-Directed Study Of Irinotecan Dosing In FOLFIRI + BevacizumabTreated Metastatic Colorectal Cancer

100 enrolled 13 charts

Colonic Neoplasms

NCT01652196 2025-02-05

Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer

56 enrolled 14 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01814501 2025-02-05

Panitumumab and Chemotherapy in Patients With Advanced Colorectal Cancer After Prior Therapy With Bevacizumab

16 enrolled 11 charts

Colonic Neoplasms, Rectal Neoplasms

NCT02431676 2024-08-28

SPIRIT

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

121 enrolled 12 charts

Breast Neoplasms, Colonic Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Endometrial Neoplasms

NCT01855607 2024-07-11

Topical Menthol for the Treatment of Chemotherapy Induced Peripheral Neuropathy

12 enrolled 5 charts

BreastGastrointestinal

Breast Neoplasms, Colonic Neoplasms

NCT03631641 2024-07-01

Nivolumab in Preventing Colon Adenomas in Participants With Lynch Syndrome and a History of Partial Colectomy

3 enrolled 5 charts

Phase 2 Active not recruiting

Colonic Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis

NCT03992456 2024-05-21

Panitumumab, Regorafenib, or TAS-102, in Treating Patients With Metastatic and/or Unresectable RAS Wild-Type Colorectal Cancer

12 enrolled 16 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00321828 2024-03-21

Combination Chemotherapy and Bevacizumab in Treating Patients With Stage IV Colon Cancer That Cannot Be Removed By Surgery

90 enrolled 6 charts

Colonic Neoplasms, Colorectal Neoplasms

NCT00407654 2024-03-04

VEGF Trap in Treating Patients With Previously Treated Metastatic Colorectal Cancer

75 enrolled 15 charts

Colonic Neoplasms, Rectal Neoplasms

NCT04171700 2023-10-02

LODESTAR

BreastGastrointestinalGenitourinaryGynecologicSarcomaThoracic

83 enrolled 16 charts

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinosarcoma, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Fallopian Tube Neoplasms, Leiomyosarcoma, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT00098787 2023-07-05

Bevacizumab and Oxaliplatin Combined With Irinotecan or Leucovorin and Fluorouracil in Treating Patients With Metastatic or Recurrent Colorectal Cancer

247 enrolled 10 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01079780 2023-06-28

Irinotecan Hydrochloride and Cetuximab With or Without Ramucirumab in Treating Patients With Advanced Colorectal Cancer With Progressive Disease After Treatment With Bevacizumab-Containing Chemotherapy

136 enrolled 13 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT03428126 2023-06-15

Study of Durvalumab (MEDI4736) (Anti-PD-L1) and Trametinib (MEKi) in MSS Metastatic Colon Cancer

29 enrolled 9 charts

Colonic Neoplasms, Colorectal Neoplasms

NCT03801915 2023-03-21

Perioperative MVT-5873, a Fully Human Monoclonal Antibody Against a CA 19-9 Epitope, for Operable CA 19-9 Producing Pancreatic Cancers, Cholangiocarcinomas, and Metastatic Colorectal Cancers

10 enrolled 14 charts

Colonic Neoplasms, Pancreatic Neoplasms, Cholangiocarcinoma

NCT00819780 2022-12-06

PEAK: Panitumumab Plus mFOLFOX6 vs. Bevacizumab Plus mFOLFOX6 for First Line Treatment of Metastatic Colorectal Cancer (mCRC) Patients With Wild-Type Kirsten Rat Sarcoma-2 Virus (KRAS) Tumors

285 enrolled 31 charts

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00089635 2022-11-07

Panitumumab (ABX-EGF) Monotherapy in Patients With Metastatic Colorectal Cancer

203 enrolled 14 charts

Colonic Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT01464593 2022-10-13

ABLATE

2 enrolled 5 charts

Colonic Neoplasms, Liver Neoplasms

NCT00193219 2022-01-11

Bevacizumab and Cetuximab in Combination With FOLFOX6 in Patients With Metastatic Colorectal Cancer

36 enrolled 8 charts

Colonic Neoplasms

NCT01505166 2021-11-01

FANG-CLM

3 enrolled 9 charts

Colonic Neoplasms, Colorectal Neoplasms

NCT00314353 2021-10-06

Study of Bevacizumab Combined With Capecitabine and Either Oxaliplatin or Irinotecan as First Course of Treatment for Patients With Colorectal Cancer That Has Spread Beyond the Colon

7 enrolled 5 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01535040 2021-09-28

Memantine Hydrochloride in Helping Cancer Survivors Stop Smoking

BreastGastrointestinalGenitourinaryThoracic

130 enrolled 12 charts

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Tobacco Use Disorder, Colorectal Neoplasms

NCT01006369 2021-09-21

Hydroxychloroquine, Capecitabine, Oxaliplatin, and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer

38 enrolled 12 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00361842 2021-07-02

Multicenter Study Of CPX-1 (Irinotecan HCl: Floxuridine) Liposome Injection In Patients With Advanced Colorectal Cancer

65 enrolled 10 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01902953 2021-06-23

Lymphoseek® as Lymphoid Tissue Targeting Agents in Colon Cancer(CNC)

16 enrolled 5 charts

Colonic Neoplasms, Rectal Neoplasms

NCT00748215 2020-12-02

Calcium Aluminosilicate Anti-Diarrheal in Treating and Preventing Diarrhea in Patients With Metastatic Colorectal Cancer Receiving Irinotecan

100 enrolled 17 charts

Colonic Neoplasms, Diarrhea, Rectal Neoplasms, Colorectal Neoplasms

NCT00192114 2020-08-06

Enzastaurin for Patients With Metastatic Colorectal Cancer

28 enrolled 18 charts

Colonic Neoplasms

NCT01471353 2020-07-23

SorCape

43 enrolled 12 charts

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms

NCT01363843 2020-06-11

Complete Neoadjuvant Treatment for REctal Cancer (CONTRE)

39 enrolled 7 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01802320 2019-09-20

Akt Inhibitor MK2206 in Treating Patients With Previously Treated Colon or Rectal Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery

18 enrolled 7 charts

Colonic Neoplasms, Rectal Neoplasms

NCT01662752 2019-08-09

Lymphatic Mapping for Sentinel Node Identification and Analysis

30 enrolled 5 charts

Colonic Neoplasms, Colorectal Neoplasms

NCT01111604 2019-08-06

A Study of Ramucirumab or Icrucumab in Colorectal Cancer

158 enrolled 17 charts

Adenocarcinoma, Colonic Neoplasms, Rectal Neoplasms

NCT00940316 2019-05-07

Dual Epidermal Growth Factor Receptor Inhibition With Erlotinib and Panitumumab With or Without Chemotherapy for Advanced Colorectal Cancer

28 enrolled 11 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01925274 2019-01-08

A Study Of PF-05212384 Plus Irinotecan Vs Cetuximab Plus Irinotecan In Patients With KRAS And NRAS Wild Type Metastatic Colorectal Cancer

19 enrolled 32 charts

Colonic Neoplasms, Colorectal Neoplasms

NCT02305758 2018-11-20

Study Comparing Veliparib Plus FOLFIRI Versus Placebo Plus FOLFIRI With or Without Bevacizumab in Previously Untreated Metastatic Colorectal Cancer

130 enrolled 12 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00257322 2018-10-31

Cellular Immune Augmentation in Colon and Rectal Cancer

20 enrolled 6 charts

Colonic Neoplasms, Rectal Neoplasms

NCT00094809 2018-10-17

Chemotherapy Administered Every 2 Weeks With or Without Pegfilgrastim in Subjects With Advanced or Metastatic Colon Cancer

252 enrolled 19 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00418938 2018-10-17

SPIRITT - Second-Line Panitumumab Irinotecan Treatment Trial

266 enrolled 17 charts

Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00896454 2018-10-17

Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium

BreastGastrointestinalGenitourinaryHead & NeckLymphoidPlasma cellThoracic

33 enrolled 22 charts

Humoral Hypercalcemia Of Malignancy, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Endocrine Gland Neoplasms, Head and Neck Neoplasms, Hodgkin Disease, Hypercalcemia, Kidney Neoplasms, Lung Neoplasms, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Parathyroid Neoplasms, Thyroid Neoplasms

NCT00310076 2018-08-23

Thalidomide in Treating Patients Who Have Undergone Surgery and Chemotherapy for Cancer That Has Spread Throughout the Abdomen Due to Colorectal Cancer or Appendix Cancer

29 enrolled 9 charts

Appendiceal Neoplasms, Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01729923 2018-01-16

ADAPT

27 enrolled 10 charts