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Phase 3 × Colonic Neoplasms × Temozolomide × Clear all

Phase

Phase 3 1 Phase 1/2 1

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Gastrointestinal 1

Conditions

Glioblastoma 35 Brain Neoplasms 15 Astrocytoma 15 Central Nervous System Neoplasms 9 Oligodendroglioma 8 Gliosarcoma 8 Melanoma 6 Glioma 6 Recurrence 4 Neoplasms 3 Neoplasm Metastasis 2 Diffuse Intrinsic Pontine Glioma 2 Choroid Plexus Neoplasms 2 Carcinoma, Non-Small-Cell Lung 2 Sarcoma, Ewing 1 Sarcoma 1 Rhabdoid Tumor 1 Rare Diseases 1 Optic Nerve Glioma 1 Neurotoxicity Syndromes 1 Neuroendocrine Tumors 1 Neuroectodermal Tumors, Primitive, Peripheral 1 Neuroblastoma 1 Neoplasms, Neuroepithelial 1 Neoplasms, Connective and Soft Tissue 1 Neoplasms, Connective Tissue 1 Neoplasms, Bone Tissue 1 Neoplasms by Histologic Type 1 Melanoma Neuroendocrine Tumors Neuroectodermal Tumors Neoplasms Germ Cell and Embryonal Neoplasms by Histologic Type Neoplasms Neoplasms 1 Lymphoma, Follicular 1

Interventions

Fluorouracil 57 Leucovorin 56 Oxaliplatin 38 Irinotecan 25 Folfox protocol 19 Capecitabine 18 Bevacizumab 17 Cetuximab 12 Chemotherapy, Adjuvant 11 Aspirin 6 Laparoscopy 5 Celecoxib 5 XELOX 4 dehydroftorafur 3 Panitumumab 3 Observation 3 Levamisole 3 Floxuridine 3 pertuzumab 2 encorafenib 2 atezolizumab 2 Trastuzumab 2 Tegafur 2 Standard of Care 2 Octreotide 2 Occult Blood 2 Nivolumab 2 Neoadjuvant Therapy 2 Mitomycin 2 Immunoglobulin G 2

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT06490536 2025-08-29

The Sagittarius Trial

IFOM ETS - The AIRC Institute of Molecular Oncology

Phase 3 Recruiting

Gastrointestinal

Colonic Neoplasms

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