Clinical Trials

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT05806931 2026-03-18

SCOTI

50 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT06802991 2026-03-18

Optimised Post-discharge Care in Older Patients After Surgery for Colon Cancer (ERAS 3.0)

60 enrolled

Frailty, Colonic Neoplasms

NCT07284849 2026-03-16

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

Phase 3 Recruiting

700 enrolled

Colonic Neoplasms, Colorectal Neoplasms

NCT00905047 2026-03-13

COLOCROSS

Phase 3 Completed

89 enrolled

Phase 1 Active not recruiting

Colonic Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT06607185 2026-03-13

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

750 enrolled

GastrointestinalGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT06704724 2026-03-13

A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene.

Phase 1 Active not recruiting

30 enrolled

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT06567782 2026-03-12

AZUR-4

120 enrolled

Colonic Neoplasms

NCT07468630 2026-03-12

TRIUNITE-08

106 enrolled

Phase EARLY_PHASE1 Active not recruiting

Colonic Neoplasms

NCT06011772 2026-03-11

EGF-Depleting Therapy CIMAvax-EGF in Combination With Standard Therapy for RAS- and BRAF Wild-Type Metastatic Colorectal Cancer

2 enrolled

Phase NA Enrolling by invitation

Colonic Neoplasms

NCT06191185 2026-03-11

IMPACTT

2,000 enrolled

Phase 3 Active not recruiting

Colonic Neoplasms, Colorectal Neoplasms

NCT01918527 2026-03-10

Neoadjuvant Chemotherapy Versus Standard Treatment in Patients With Locally Advanced Colon Cancer

250 enrolled

Colonic Neoplasms

NCT03446157 2026-03-10

Palbociclib and Cetuximab in Metastatic Colorectal Cancer

Phase 2 Completed

24 enrolled 14 charts

Phase 2/3 Not yet recruiting

Colonic Neoplasms

NCT07462143 2026-03-10

A Phase Ⅱ/Ⅲ Clinical Trial of RC148 Plus Chemotherapy as 1L Therapy for Unresectable or Metastatic Colorectal Cancer

700 enrolled

Colonic Neoplasms

NCT00102011 2026-03-09

00-046

Phase 3 Completed

4,952 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT05677048 2026-03-09

Feasibility Study: IGNITE-TX (Identifying Individuals for Genetic Testing & Treatment) Intervention

BreastGastrointestinalGynecologic

205 enrolled

Breast Neoplasms, Colonic Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Ovarian Neoplasms, Pancreatic Neoplasms, Uterine Neoplasms, Endometrial Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT06835569 2026-03-09

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

188 enrolled

Carcinoma, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Pancreatic Neoplasms, Colorectal Neoplasms

NCT06281925 2026-03-06

Cryotherapy & Oxaliplatin

Phase NA Suspended

40 enrolled

Colonic Neoplasms, Peripheral Nervous System Diseases

NCT07432399 2026-03-06

PILDI

100 enrolled

Colonic Neoplasms, Colorectal Neoplasms

NCT03026140 2026-03-05

NICHE

353 enrolled

Colonic Neoplasms

NCT03151564 2026-03-05

Lesion Detection Assessment in the Liver: Standard vs Low Radiation Dose Using Varied Post-Processing Techniques

146 enrolled

Colonic Neoplasms, Digestive System Diseases, Colorectal Neoplasms

NCT05433142 2026-03-05

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

GastrointestinalGenitourinaryThoracic

307 enrolled

Carcinoma, Renal Cell, Colonic Neoplasms, Kidney Neoplasms, Lung Neoplasms

NCT05672108 2026-03-05

Phase II Trial of Lung Chemoemobolization

GastrointestinalSarcomaThoracic

30 enrolled

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Mediastinal Neoplasms, Pleural Neoplasms, Sarcoma

NCT05722327 2026-03-04

Phase I Trial of Adagrasib (MRTX849) in Combination With Cetuximab and Irinotecan in Patients With Colorectal Cancer

Phase 1 Active not recruiting

24 enrolled

Colonic Neoplasms, Colorectal Neoplasms

NCT05080673 2026-03-03

FORTE

9,500 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT05174169 2026-03-03

CIRCULATE-US

Phase 2/3 Recruiting

1,912 enrolled

Colonic Neoplasms

NCT07321106 2026-03-03

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

80 enrolled

Phase 1/2 Active not recruiting

Colonic Neoplasms, Neoplasms, Colorectal Neoplasms

NCT04068610 2026-03-02

COLUMBIA-1: Novel Oncology Therapies in Combination With Chemotherapy and Bevacizumab as First- Line Therapy in MSS-CRC

61 enrolled 35 charts

Colonic Neoplasms

NCT05108298 2026-03-02

Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials

BreastCNSDermatologicGastrointestinalGynecologicHead & NeckLymphoidOther hematologic neoplasmSarcoma

400 enrolled

Bone Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Leukemia, Lymphoma, Melanoma, Sarcoma, Thyroid Neoplasms, Central Nervous System Neoplasms, Pyloric Stenosis, Hypertrophic

NCT06447662 2026-02-25

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

330 enrolled

Phase NA Not yet recruiting

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT07406087 2026-02-25

Navigation Intervention for Adolescent and Young Adult Cancer Survivors

25 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcoma

Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Melanoma, Ovarian Neoplasms, Sarcoma, Testicular Neoplasms, Thyroid Neoplasms, Endometrial Neoplasms

NCT05579340 2026-02-24

POET-mCRC

66 enrolled

GastrointestinalGynecologic

Colonic Neoplasms

NCT06625515 2026-02-24

First-in-Human Study of ATX-559, an Oral Inhibitor of DHX9, in Patients With Advanced or Metastatic Solid Tumors, and Molecularly Defined Cancers

Phase 1 Terminated

17 enrolled

Colonic Neoplasms, Rectal Neoplasms, Endometrial Neoplasms, Microsatellite Instability

NCT04426669 2026-02-23

A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering

Phase 1/2 Completed

23 enrolled

Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT07427537 2026-02-23

miR-CIPN#1

90 enrolled

Colonic Neoplasms, Lung Neoplasms, Neuritis, Colorectal Neoplasms

NCT07427901 2026-02-23

Quality Of Life In Colorectal Cancer Survivors

368 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT07428239 2026-02-23

Pilot Study of Individualized Comprehensive Rehabilitation in Patients With Colorectal Cancer

Phase NA Completed

150 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT03523546 2026-02-20

Oncology Episode Payment Model in Hawaii

BreastGastrointestinalThoracic

7 enrolled

Breast Neoplasms, Colonic Neoplasms, Lung Neoplasms

NCT04258813 2026-02-20

ONE TEAM

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

313 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Cardiovascular Diseases, Colonic Neoplasms, Diabetes Mellitus, Esophageal Neoplasms, Head and Neck Neoplasms, Hypercholesterolemia, Hypertension, Liver Neoplasms, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms

NCT04907643 2026-02-20

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

EndocrineGastrointestinalNET

360 enrolled

Cancer Pain, Anus Neoplasms, Appendiceal Neoplasms, Bile Duct Neoplasms, Biliary Tract Neoplasms, Carcinoid Tumor, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Stomach Neoplasms, Neuroendocrine Tumors, Visceral Pain

NCT06051695 2026-02-20

EVEREST-2

Phase 1/2 Recruiting

474 enrolled

GastrointestinalGynecologicOther solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Colorectal Neoplasms

NCT06446557 2026-02-20

DIAMOND

Phase 3 Not yet recruiting

408 enrolled

Phase 2 Not yet recruiting

Colonic Neoplasms

NCT07409844 2026-02-20

RESET C2

152 enrolled

Colonic Neoplasms

NCT05578092 2026-02-19

A Phase 1 Study of MRTX0902 in Solid Tumors With Mutations in the KRAS MAPK Pathway

Phase 1 Terminated

64 enrolled