Clinical Trials Browser

Phase 3 × Colorectal Neoplasms, Hereditary Nonpolyposis × Clear all

NCT02912559 2026-02-02

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

Phase 3 Active not recruiting

712 enrolled

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, DNA Repair-Deficiency Disorders

NCT02000089 2025-10-09

CAPS5

Phase 3 Recruiting

9,000 enrolled

BreastGastrointestinal

Hereditary pancreatitis, Breast Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Dysplastic Nevus Syndrome, Hereditary Sensory and Autonomic Neuropathies, Pancreatic Neoplasms, Peutz-Jeghers Syndrome

NCT04711434 2021-01-20

PD-1 Antibody for The Prevention of Adenomatous Polyps and Second Primary Tumors in Lynch Syndrome Patients

Phase 3 Unknown

260 enrolled

Gastrointestinal

Colorectal Neoplasms, Hereditary Nonpolyposis

NCT00566644 2013-07-10

Intrauterine Levonorgestrel and Observation or Observation Alone in Preventing Atypical Endometrial Hyperplasia and Endometrial Cancer in Women With Hereditary Non-Polyposis Colorectal Cancer or Lynch Syndrome

Phase 3 Terminated

600 enrolled

GastrointestinalGynecologic

Colorectal Neoplasms, Hereditary Nonpolyposis, Endometrial Neoplasms