Clinical Trials

Phase 2 Active not recruiting

Attenuated familial adenomatous polyposis, Duodenal Neoplasms, Adenomatous Polyposis Coli, Colorectal Neoplasms

NCT05419011 2026-03-18

Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome

186 enrolled

Colorectal Neoplasms, Hereditary Nonpolyposis, Colorectal Neoplasms

NCT05630794 2026-03-18

Testing for Safety and Colorectal Cancer Preventive Effects of ONC201

36 enrolled

Adenomatous Polyposis Coli, Colorectal Neoplasms

NCT05691491 2026-03-18

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

Phase 1/2 Recruiting

58 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT05803382 2026-03-18

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

30 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT06102902 2026-03-18

Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer

30 enrolled

Phase 2 Not yet recruiting

Colorectal Neoplasms

NCT06557733 2026-03-18

An Investigational Drug (TPST-1495) in Patients With Familial Adenomatous Polyposis

38 enrolled

Adenomatous Polyposis Coli, Colorectal Neoplasms

NCT06654037 2026-03-18

Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

39 enrolled

Colorectal Neoplasms

NCT06696768 2026-03-18

Clinical Trial of an Anti-cancer Drug, CA-4948 (Emavusertib), in Combination With Chemotherapy Treatment (FOLFOX Plus Bevacizumab) in Metastatic Colorectal Cancer

24 enrolled

Colorectal Neoplasms

NCT06269978 2026-03-10

Intraperitoneal Oxaliplatin and Fluorouracil for the Treatment of Patients With Peritoneal Metastases From Colorectal Cancer

24 enrolled

Phase 1/2 Active not recruiting

Colorectal Neoplasms

NCT05078866 2026-03-03

Cancer Preventive Vaccine Nous-209 for Lynch Syndrome Patients

45 enrolled

Phase 2 Active not recruiting

Colorectal Neoplasms, Hereditary Nonpolyposis, Colorectal Neoplasms

NCT04767984 2026-01-21

Testing Atorvastatin to Lower Colon Cancer Risk in Longstanding Ulcerative Colitis

42 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Colitis, Ulcerative, Colorectal Neoplasms

NCT07327489 2026-01-08

ELEPHAS-05

Recruiting

2,000 enrolled

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Melanoma, Neoplasms, Skin Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT06626256 2025-12-24

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Phase 1 Withdrawn

DermatologicGastrointestinalGenitourinaryGynecologic

Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms

NCT04729322 2025-12-23

Fecal Microbiota Transplant and Re-introduction of Anti-PD-1 Therapy (Pembrolizumab or Nivolumab) for the Treatment of Metastatic Colorectal Cancer in Anti-PD-1 Non-responders

Phase 2 Active not recruiting

15 enrolled

Phase 3 Not yet recruiting

Colorectal Neoplasms

NCT07271355 2025-12-09

Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial

129 enrolled

Appendiceal Neoplasms, Colorectal Neoplasms

NCT06730100 2025-10-06

CBX-12 for the Treatment of Metastatic Chemotherapy-Refractory Microsatellite Stable Colorectal Cancer

Phase 2 Withdrawn

Colorectal Neoplasms

NCT06130826 2025-05-30

Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer

24 enrolled

BreastGastrointestinal

Breast Neoplasms, Colorectal Neoplasms

NCT06425133 2024-12-24

CARE

Phase 2 Recruiting

174 enrolled

Phase 1 Active not recruiting

Colonic Neoplasms, Colorectal Neoplasms

NCT04535401 2024-10-10

Testing the Addition of an Anticancer Drug, BAY 1895344, to the Usual Chemotherapy With FOLFIRI in Advanced or Metastatic Cancers of the Stomach and Intestines

10 enrolled

Stomach Neoplasms, Colorectal Neoplasms

NCT05518032 2024-09-26

Pembrolizumab and Autologous Dendritic Cells for the Treatment of Refractory Colorectal Cancer (CRC)

Phase 2 Withdrawn

Colorectal Neoplasms

NCT03089268 2023-10-02

SERRACOLON

Active not recruiting

700 enrolled

Colonic Neoplasms, Colonic Polyps, Colorectal Neoplasms

NCT00470353 2023-08-04

Cholecalciferol and Calcium Carbonate in Treating Patients With Colon Cancer That Has Been Removed by Surgery

Phase NA Terminated

8 enrolled

Colonic Neoplasms, Colorectal Neoplasms

NCT05945082 2023-07-14

Fusobacterium Nucleatum at Colorectal Cancer Sites

Phase NA Unknown

150 enrolled

Periodontitis, Colorectal Neoplasms

NCT03563651 2021-11-18

Collection of Blood, Urine, and Stool to Monitor MetastaticColorectal Cancers

29 enrolled

DermatologicGastrointestinal

Colorectal Neoplasms

NCT01336985 2019-12-17

Safety and Pharmacokinetics of Treating Liver Cancer With Drug-Eluting Beads

Phase 1 Terminated

5 enrolled

Liver Neoplasms, Melanoma, Neoplasm Metastasis, Colorectal Neoplasms

NCT02332213 2018-08-21

VOLGACORE

2,022 enrolled

Adenoma, Gastritis, Atrophic, Gastrointestinal Neoplasms, Peptic Ulcer, Stomach Neoplasms, Colorectal Neoplasms

NCT03228095 2018-08-21

Volatolome

Unknown

3,000 enrolled

Gastritis, Atrophic, Gastrointestinal Neoplasms, Influenza, Human, Liver Cirrhosis, Liver Neoplasms, Pancreatic Neoplasms, Peptic Ulcer, Stomach Neoplasms, Tuberculosis, Colorectal Neoplasms, Inflammatory Bowel Diseases, Pancreatitis, Chronic

NCT00550628 2015-12-23

Fludeoxyglucose F 18 PET Imaging in Determining Protein and Gene Expression Signatures in Patients With Premalignant Polyps or Colon Cancer

8 enrolled

Colonic Neoplasms, Colorectal Neoplasms

NCT00390364 2014-10-08

Everolimus in Treating Patients With Advanced or Metastatic Colorectal Cancer That Did Not Respond to Previous Therapy

Phase 2 Terminated

1 enrolled 7 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00369109 2013-04-08

Skin Biopsies and DNA Analysis in Patients Receiving Irinotecan or Gemcitabine For Advanced Solid Tumors

60 enrolled

BreastGastrointestinal

Breast Neoplasms, Colonic Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00608595 2013-03-05

Celecoxib in Treating Patients With Early-Stage Rectal Cancer

Phase NA Terminated

10 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00513266 2009-08-07

Combination Chemotherapy and Monoclonal Antibody Therapy in Treating Patients With Advanced Colorectal Cancer With Liver Metastases or Lung Metastases That Are Potentially Removable by Surgery

Phase 2 Unknown

35 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00331786 2009-02-09

Nitric Oxide-Releasing Acetylsalicyclic Acid in Preventing Colorectal Cancer in Patients at High Risk of Colorectal Cancer

Phase 1 Completed

240 enrolled