Clinical Trials Browser

Phase 3 × Colorectal Neoplasms × Oxaliplatin × Clear all

NCT02997228 2026-03-18

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Phase 3 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT05253651 2026-03-16

MOUNTAINEER-03

Phase 3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT05239741 2026-03-10

MK-3475-C66

Phase 3 Recruiting

Gastrointestinal

Parkinson Disease 4, Autosomal Dominant Lewy Body, Colorectal Neoplasms

NCT04230187 2026-03-05

TRIBE-C

Phase 3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07228832 2026-03-03

HARMONi-GI3

Phase 3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT05863195 2026-03-02

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Phase 3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT05171660 2026-02-17

Combination With Sintilimab and XELOX+Bevacizumab as 1st Line Therapy in RAS-mutant Metastatic Colorectal Cancer

Phase 3 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT04854668 2026-01-30

A Study of Anlotinib Hydrochloride Capsule Combined With Chemotherapy as First-line Treatment in Subjects With RAS/BRAF Wild Metastatic Colorectal Cancer

Phase 3 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT05008809 2025-12-12

AIO-KRK-0418

Phase 3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06733038 2025-12-08

AtezoTRIBE2

Phase 3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06783491 2025-11-24

FOXHIPECT4

Phase 3 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT04008030 2025-10-03

CheckMate 8HW

Phase 3 Active not recruiting

839 enrolled 22 charts 1 FDA

Gastrointestinal

Colorectal Neoplasms

NCT04607421 2025-08-14

A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

Phase 3 Active not recruiting

831 enrolled 2 FDA

Gastrointestinal

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Rectal Diseases, Rectal Neoplasms, Colorectal Neoplasms

NCT02885753 2025-07-09

OSCAR

Phase 3 Recruiting

Gastrointestinal

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT07025239 2025-06-17

QL1706 Injection Plus Bevacizumab and XELOX vs Placebo Plus Bevacizumab and XELOX as First-Line Treatment of Unresectable Metastatic Colorectal Cancer

Phase 3 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT04861558 2025-05-30

EFFIPEC

Phase 3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT01167725 2024-12-27

Standard Therapy With or Without Surgery and Mitomycin C in Treating Patients With Advanced Limited Peritoneal Dissemination of Colon Cancer

Phase 3 Terminated

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT05954078 2024-05-20

Circulating Tumor DNA Methylation Guided Postoperative Adjuvant Chemotherapy for High-risk Stage II/III Colorectal Cancer

Phase 3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT02394795 2023-11-01

PARADIGM

Phase 3 Completed

823 enrolled 20 charts

Gastrointestinal

Colorectal Neoplasms

NCT05081687 2023-10-11

BRAZIL-TNT

Phase 3 Unknown

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00958737 2023-09-29

IDEA

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT03950154 2023-08-01

Study of Chemotherapy Combination With Autologous Cell Immunotherapy in the Recurrent and Metastatic Colorectal Cancer

Phase 3 Unknown

Gastrointestinal

Colorectal Neoplasms

NCT00202774 2023-04-12

Safety and Efficacy Study of XELOX vs. Oxaliplatin+5-FU CI as First Line Treatment in Metastatic Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT01718873 2023-04-12

OBELICS

Phase 3 Completed

230 enrolled 12 charts

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT05699746 2023-01-26

CAPEOX vs Observation in Colorectal Cancer Patients With Positive MRD

Phase 3 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT03231722 2023-01-05

TRIPLETE

Phase 3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT05236972 2022-12-30

PACE: PD-1 Antibody For dMMR/MSI-H Stage III Colorectal Cancer

Phase 3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT02121405 2022-05-11

PSSR

Phase 3 Suspended

Gastrointestinal

Radiation Injuries, Colorectal Neoplasms

NCT01150045 2022-03-22

Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery

Phase 3 Unknown

2,527 enrolled 14 charts

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT00070213 2021-09-27

Leucovorin and Fluorouracil With or Without Oxaliplatin Compared to Capecitabine With or Without Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00227747 2021-02-17

Radiation Therapy and Capecitabine With or Without Oxaliplatin in Treating Patients Who Are Undergoing Surgery for Stage II or Stage III Rectal Cancer

Phase 3 Completed

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT03300609 2020-06-11

5-FU Based Maintenance Therapy in RAS Wild Type Metastatic Colorectal Cancer After Induction With FOLFOX Plus Panitumumab

Phase 3 Terminated

Gastrointestinal

Colorectal Neoplasms

NCT00265850 2020-05-07

Cetuximab and/or Bevacizumab Combined With Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer

Phase 3 Completed

2,334 enrolled 9 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00003594 2020-04-29

Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00069121 2020-03-06

A Study of Xeloda (Capecitabine) Plus Oxaliplatin in Patients With Colon Cancer

Phase 3 Completed

1,886 enrolled 16 charts

Gastrointestinal

Colorectal Neoplasms

NCT03448549 2020-03-06

SOX Versus XELOX as Adjuvant Chemotherapy for Stage III Colorectal Cancer Patients

Phase 3 Unknown

Gastrointestinal

Patient Compliance, Colorectal Neoplasms

NCT02339116 2020-02-05

TRIBE2

Phase 3 Unknown

Gastrointestinal

Colorectal Neoplasms

NCT01228734 2020-01-28

TAILOR

Phase 3 Completed

553 enrolled 13 charts

Gastrointestinal

Colorectal Neoplasms

NCT00115765 2018-10-17

PACCE: Panitumumab Advanced Colorectal Cancer Evaluation Study

Phase 3 Completed

1,053 enrolled 25 charts

Gastrointestinal

Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00749450 2018-07-27

Combination Chemotherapy After Surgery in Treating Patients With High-Risk Stage II or Stage III Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00077233 2018-05-16

FOLFIRI or FOLFOX With or Without Cetuximab in Patients With Metastatic Adenocarcinoma of the Colon or Rectum

Phase 3 Terminated

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01279681 2017-12-08

Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer

Phase 3 Terminated

32 enrolled 14 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Neurotoxicity Syndromes

NCT01308086 2017-08-09

Adjuvant Therapy(3 vs. 6 Months) With the FOLFOX 4 or XELOX for Stage II or Stage III Colon Cancer

Phase 3 Unknown

Gastrointestinal

Neoplasms, Colorectal Neoplasms

NCT00399035 2016-12-28

HORIZON II

Phase 3 Completed

1,254 enrolled 14 charts

Gastrointestinal

Colorectal Neoplasms

NCT00766155 2016-10-12

PETACC-6

Phase 3 Completed

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00069095 2016-10-06

A Study of Capecitabine (Xeloda) and Bevacizumab as a First-line Therapy in Patients With Metastatic Colorectal Cancer

Phase 3 Completed

2,035 enrolled 33 charts

Gastrointestinal

Colorectal Neoplasms

NCT00769405 2016-08-30

Systemic Chemotherapy With or Without Intraperitoneal Chemohyperthermia in Treating Patients Undergoing Surgery for Peritoneal Carcinomatosis From Colorectal Cancer

Phase 3 Completed

GastrointestinalGynecologic

Colonic Neoplasms, Peritoneal Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT02785146 2016-06-08

Adjuvant Chemotherapy Combined With Huaier Granule for Treating High-risk Stage II, Stage III Colorectal Cancer

Phase 3 Unknown

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT00305188 2016-05-04

Evaluation of the Efficacy of Xaliproden (SR57746A) in Preventing the Neurotoxicity of Oxaliplatin / 5FU/LV Chemotherapy.

Phase 3 Completed

Gastrointestinal

Neoplasm Metastasis, Paresthesia, Colorectal Neoplasms, Neurotoxicity Syndromes

NCT00058474 2016-03-23

Radiation Therapy and Either Capecitabine or Fluorouracil With or Without Oxaliplatin Before Surgery in Treating Patients With Resectable Rectal Cancer

Phase 3 Unknown

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms