Clinical Trials Browser

Colorectal Neoplasms × Radiotherapy × Clear all

NCT02888743 2026-03-18

Durvalumab and Tremelimumab With or Without High or Low-Dose Radiation Therapy in Treating Patients With Metastatic Colorectal or Non-small Cell Lung Cancer

Phase 2 Active not recruiting

110 enrolled 21 charts

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms

NCT07467590 2026-03-12

TRIUNITE-07

Phase 2 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07448142 2026-03-04

Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07448662 2026-03-04

COLBRAIN

Active not recruiting

CNSGastrointestinal

Brain Neoplasms, Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00335816 2026-01-14

Radiation Therapy and Fluorouracil With or Without Combination Chemotherapy Followed by Surgery in Treating Patients With Stage II or Stage III Rectal Cancer

Phase 2 Active not recruiting

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT06356584 2025-06-26

Fruquintinib Combined With Sintilimab ± Radiotherapy for Third-line Treatment of Colorectal Cancer With Liver Metastases

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT05704985 2025-05-29

Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors

Phase 1 Active not recruiting

DermatologicGastrointestinalGenitourinaryHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Kidney Neoplasms, Neoplasms, Pancreatic Neoplasms, Skin Neoplasms, Colorectal Neoplasms

NCT06991465 2025-05-28

Hypo-OPRA

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06848465 2025-05-11

LDRT Combined With Immunochemotherapy for Colorectal Cancer With Liver Metastasis

Phase 1 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06120127 2023-11-07

IMPROVE

Phase 2 Unknown

Gastrointestinal

Colorectal Neoplasms

NCT06099951 2023-10-25

Total Neoadjuvant Treatment for pMMR Locally Advanced Low Rectal Cancer: Anti-PD-1 Antibody With FOLFOXIRI and Preoperative Radiation Therapy

Phase 2 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT02535988 2023-09-21

Abscopal Effect for Metastatic Colorectal Cancer

Phase 2 Withdrawn

Gastrointestinal

Colorectal Neoplasms

NCT04304209 2023-02-01

Pd1 Antibody Sintilimab ± Chemoradiotherapy for Locally Advanced Rectal Cancer

Phase 2 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT03122509 2022-07-06

A Clinical Trial of Durvalumab and Tremelimumab, Administered With Radiation Therapy or Ablation in Patients With Colorectal Cancer

Phase 2 Completed

25 enrolled 7 charts

Gastrointestinal

Colorectal Neoplasms

NCT01759238 2022-07-01

OLGA

Phase 2 Terminated

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT02121405 2022-05-11

PSSR

Phase 3 Suspended

Gastrointestinal

Radiation Injuries, Colorectal Neoplasms

NCT05292417 2022-03-31

Radiotherapy in Combination With Sintilimab，GM-CSF and Fruquintinib in Patients With MSS mCRC

Phase 2 Unknown

Gastrointestinal

Colorectal Neoplasms

NCT05160727 2021-12-20

Radiotherapy Combined With Tislelizumab and Irinotecan in MSS/pMMR Recurrence and Metastatic Colorectal Cancer

Phase 2 Unknown

Gastrointestinal

Colorectal Neoplasms

NCT00308516 2021-12-10

5-Fluorouracil, Bevacizumab, and Radiation Followed by Modified FOLFOX6 and Bevacizumab in Stage II/III Rectal Cancer

Phase 2 Completed

66 enrolled 6 charts

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00227747 2021-02-17

Radiation Therapy and Capecitabine With or Without Oxaliplatin in Treating Patients Who Are Undergoing Surgery for Stage II or Stage III Rectal Cancer

Phase 3 Completed

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT01224392 2020-12-30

RectumSIB

Phase 3 Completed

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT02010567 2020-11-03

Neoadjuvant Chemoradiotherapy With CRLX-101 and Capecitabine for Rectal Cancer

Phase 1/2 Terminated

32 enrolled 18 charts

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00006366 2020-10-22

Radiation Therapy Plus Chemotherapy Followed by Surgery in Treating Patients With Locally Advanced Cancer of the Rectum

Phase 2 Completed

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00021398 2020-06-05

Radiation Therapy and Chemotherapy Followed by Surgery and Combination Chemotherapy in Treating Patients With Rectal Cancer

Phase 2 Completed

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00081289 2020-02-27

Neoadjuvant Chemoradiotherapy and Adjuvant Chemotherapy in Treating Patients Who Are Undergoing Surgical Resection for Locally Advanced Rectal Cancer

Phase 2 Completed

146 enrolled 23 charts

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00541112 2020-02-11

Radiation Therapy, Chemotherapy, and Cetuximab Followed by Surgery, Chemotherapy, and Cetuximab in Treating Patients With Locally Advanced or Metastatic Rectal Cancer That Can Be Removed by Surgery

Phase 2 Terminated

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00869570 2019-05-15

External-Beam Radiation Therapy, Capecitabine, and Sorafenib in Treating Patients With Locally Advanced Rectal Cancer

Phase 1/2 Completed

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT03823079 2019-01-30

Comparison of Interleukin-11 and rhTPO for Recurrent Colorectal Cancer Patients With Thrombocytopenia

Phase 2 Unknown

Classical hematologyGastrointestinal

Thrombocytopenia, Colorectal Neoplasms

NCT00613080 2018-09-25

Combination Chemotherapy and Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Locally Advanced Rectal Cancer

Phase 2 Completed

79 enrolled 12 charts

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00686166 2018-05-18

S0713: Oxaliplatin, Capecitabine, Cetuximab, and RT Followed By Surgery in Pts W/Stage II or III Rectal Cancer

Phase 2 Completed

83 enrolled 8 charts

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00114231 2018-03-29

Capecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Stage I Rectal Cancer

Phase 2 Completed

90 enrolled 10 charts

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00625183 2017-11-17

Capecitabine, Oxaliplatin, Selenomethionine, and Radiation Therapy in Treating Patients Undergoing Surgery For Newly Diagnosed Stage II or III Rectal Adenocarcinoma

Phase 2 Terminated

5 enrolled 6 charts

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00004005 2017-04-26

Irinotecan Followed By Fluorouracil and Leucovorin in Treating Patients With Stage III or Stage IV Colorectal Carcinoma (Cancer), Other Refractory Carcinoma, or Metastatic Adenoma (Cancer) of Unknown Primary Origin

Phase 2 Completed

Gastrointestinal

Colonic Neoplasms, Neoplasms, Unknown Primary, Rectal Neoplasms, Colorectal Neoplasms

NCT00081224 2016-12-15

Neoadjuvant Celecoxib and Capecitabine Combined With Pelvic Irradiation in Treating Patients With Stage II or Stage III Adenocarcinoma (Cancer) of the Rectum

Phase 2 Terminated

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT01263171 2016-09-21

COPERNICUS

Phase 2 Completed

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00002523 2016-09-02

Radiation Therapy, Surgery, and Chemotherapy in Treating Patients With Rectal Cancer That Can Be Surgically Removed

Phase 3 Completed

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00296608 2016-05-30

Radiation Therapy With or Without Chemotherapy Before Surgery in Treating Patients With Stage II or Stage III Rectal Cancer

Phase 3 Completed

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00058474 2016-03-23

Radiation Therapy and Either Capecitabine or Fluorouracil With or Without Oxaliplatin Before Surgery in Treating Patients With Resectable Rectal Cancer

Phase 3 Unknown

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00462501 2016-01-20

Combination Chemotherapy and Bevacizumab With or Without Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer

Phase NA Completed

35 enrolled 6 charts

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT02202928 2015-12-28

Adoptive Cell Therapy Plus Chemotherapy and Radiation After Surgery in Treating Patients With Colorectal Cancer

Phase 2 Unknown

Gastrointestinal

Digestive System Neoplasms, Gastrointestinal Diseases, Intestinal Neoplasms, Neoplasms, Colorectal Neoplasms

NCT00004891 2015-12-22

PET and CT Scans in Patients With Locally Advanced Primary Rectal Cancer That Can Be Removed During Surgery

Phase NA Completed

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00084773 2015-12-22

Neoadjuvant Cetuximab, Fluorouracil, and Pelvic Irradiation in Treating Patients With Locally Advanced or Locally Recurrent Rectal Cancer

Phase NA Completed

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT01227707 2015-08-17

A Study of Avastin (Bevacizumab) Plus Xeloda (Capecitabine) in Patients With Locally Advanced Rectal Cancer.

Phase 2 Completed

43 enrolled 17 charts

Gastrointestinal

Colorectal Neoplasms

NCT00967655 2014-01-10

Capecitabine, Panitumumab, and Radiation Therapy With or Without Irinotecan Hydrochloride in Treating Patients Undergoing Surgery for Localized Rectal Cancer

Phase 2 Unknown

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00002801 2013-12-19

Combination Chemotherapy and Radiation Therapy in Treating Patients With Colorectal Cancer

Phase 1 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00003422 2013-12-04

Radiation Therapy Before Surgery Compared With Chemotherapy Plus Radiation After Surgery in Treating Patients With Rectal Cancer That Can Be Surgically Removed

Phase 3 Completed

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00960427 2013-04-16

Studying Biomarkers in Tumor Tissue and Blood Samples From Patients Undergoing Chemotherapy and Radiation Therapy for Stage II or Stage III Rectal Cancer That Can Be Removed By Surgery

Phase 1 Withdrawn

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00897793 2013-04-12

Growth Factor Levels in the Blood of Patients Undergoing Radiation Therapy for Epithelial Cancer

BreastCNSGastrointestinalGenitourinaryHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Colorectal Neoplasms, Esthesioneuroblastoma, Olfactory, Breast Neoplasms, Male, Small Cell Lung Carcinoma

NCT00002551 2013-04-05

SWOG-9304 Chemotherapy Plus Radiation Therapy in Treating Patients With Rectal Cancer That Has Been Surgically Removed

Phase 3 Completed

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00086931 2013-03-08

Oxaliplatin, Capecitabine, and Radiation Therapy in Treating Patients With Locally Advanced Cancer of the Rectum

Phase 1/2 Completed

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms