Clinical Trials Browser

Phase 3 × NIH × Colorectal Neoplasms × Clear all

NCT02997228 2026-03-18

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Phase 3 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT00008281 2014-01-06

Comparison of Three Chemotherapy Regimens in Treating Patients With Metastatic Colorectal Cancer

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00002692 2013-12-19

Intravenous Compared With Intrahepatic Chemotherapy in Treating Patients With Colorectal Cancer Metastatic to the Liver

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00002893 2013-12-19

Palliative Chemotherapy in Treating Patients With Advanced Colorectal Cancer

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00008060 2013-12-19

Combination Chemotherapy in Treating Patients With Unresectable Metastatic Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00021281 2013-12-19

Combination Chemotherapy With or Without SU5416 in Treating Patients With Metastatic Colorectal Cancer

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00005586 2013-12-18

Leucovorin and Fluorouracil Compared With Observation in Treating Patients With Colorectal Cancer That Has Been Surgically Removed

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00617071 2013-12-18

Personalized Screening Plans to Increase Colorectal Cancer Screening in Healthy Participants

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00893295 2013-12-18

Increasing Colorectal Cancer Screening in African Americans

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00003354 2013-12-04

Conventional Surgery Compared With Laparoscopic-Assisted Surgery in Treating Patients With Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00003422 2013-12-04

Radiation Therapy Before Surgery Compared With Chemotherapy Plus Radiation After Surgery in Treating Patients With Rectal Cancer That Can Be Surgically Removed

Phase 3 Completed

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00004150 2013-11-06

High-Dose Fluorouracil With or Without Leucovorin Compared With Standard Fluorouracil Plus Leucovorin Following Surgery in Treating Patients With Stage III Colon Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT00002896 2013-09-20

Radiation Therapy Plus Chemotherapy Before Surgery With or Without Chemotherapy After Surgery in Treating Patients With Rectal Cancer

Phase 3 Unknown

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00003063 2013-09-20

Biological Therapy With Combination Chemotherapy in Patients With Colorectal Cancer

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00002793 2013-09-17

Chemotherapy Via an Implantable Pump Compared With a Subcutaneous Port for Unresectable Liver Metastases in Patients With Resected Colorectal Cancer

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00007930 2013-08-26

Comparison of Two Types of Surgery in Treating Patients With Rectal Cancer

Phase 3 Unknown

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00427713 2013-08-26

Capecitabine and Oxaliplatin or Standard Follow-Up Care in Treating Patients Who Have Undergone Surgery for Locally Advanced Rectal Cancer

Phase 3 Completed

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT00002455 2013-08-07

Immunotherapy After Surgery in Treating Patients With Breast Cancer, Colon Cancer, or Melanoma

Phase 3 Unknown

BreastDermatologicGastrointestinal

Breast Neoplasms, Colonic Neoplasms, Melanoma, Colorectal Neoplasms

NCT00070005 2013-08-07

J-Pouch Coloanal Anastomosis Compared With Side-to-End Coloanal Anastomosis After Radiation Therapy and Surgery to Remove the Rectum in Treating Patients With Rectal Adenocarcinoma

Phase 3 Unknown

Gastrointestinal

Postoperative Complications, Rectal Neoplasms, Colorectal Neoplasms

NCT00031863 2013-08-02

Rofecoxib After Surgery in Treating Patients With Stage II or Stage III Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00427570 2013-06-24

Fluorouracil, Semustine, and Vincristine Compared With BCG in Treating Patients With Dukes' B or Dukes' C Colon Cancer That Has Been Removed By Surgery

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT00020501 2012-03-08

Chemotherapy With or Without Isolated Hepatic Perfusion With Melphalan in Treating Patients With Colorectal Cancer That Has Spread to the Liver

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT01087268 2011-07-15

Hyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy in Patients With Pelvic Cancer

Phase 3 Unknown

GastrointestinalGenitourinaryGynecologicSarcoma

Testicular Germ Cell Tumor, Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Radiation Injuries, Rectal Neoplasms, Sarcoma, Testicular Neoplasms, Vaginal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT00006479 2011-04-18

Surgery With or Without Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00091312 2009-02-09

Fluorouracil and Irinotecan With or Without Leucovorin Compared With Observation in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT00003260 2009-01-13

Combination Chemotherapy in Treating Patients With Recurrent Metastatic Colorectal Cancer

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00006468 2009-01-13

Comparing Two Combination Chemotherapy Regimens in Treating Patients With Metastatic Colorectal Cancer

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms