Clinical Trials Browser

NIH × Interventional × Diffuse Intrinsic Pontine Glioma × Clear all

NCT02359565 2026-03-18

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma

Familial ependymoma, Turcot syndrome, Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Ependymoma, Glioma, Medulloblastoma

NCT01922076 2024-01-31

Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas

Phase 1 Completed

46 enrolled 20 charts

CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Gliosarcoma

NCT03538587 2023-08-01

Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their Caregivers

Phase NA Completed

10 enrolled 16 charts

CNSOther hematologic neoplasmSarcoma

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Leukemia, Sarcoma

NCT01222754 2022-01-03

Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas

Phase 1 Completed

29 enrolled

CNS

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioma

NCT01189266 2021-10-28

Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Phase 1/2 Completed

79 enrolled 17 charts

CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Gliosarcoma

NCT00036569 2012-02-13

A Phase II Study of Pegylated Interferon Alfa 2b (PEG-Intron(Trademark)) in Children With Diffuse Pontine Gliomas

Phase 2 Completed

32 enrolled 12 charts

CNS

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Glioma