Clinical Trials Browser

Choroid Plexus Carcinoma, Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Cerebellar Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Nervous System Diseases, Nervous System Neoplasms, Oligodendroglioma, Virus Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor

NCT05957679 2026-02-12

MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment

Phase NA Recruiting

20 enrolled

CNS

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Meningioma, Neurofibroma, Spinal Cord Neoplasms

NCT05106296 2026-01-09

Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

Phase 1 Recruiting

37 enrolled

CNS

Brain Neoplasms, Ependymoma, Glioblastoma, Medulloblastoma, Neuroectodermal Tumors, Primitive

NCT04541082 2025-12-18

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

Phase 1 Recruiting

102 enrolled

CNSSarcoma

Typical Teratoid Rhabdoid Tumor, Astrocytoma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma

NCT04185038 2025-12-15

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Phase 1 Recruiting

90 enrolled

CNS

Choroid Plexus Carcinoma, Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioma, Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Pinealoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT02417324 2025-12-04

International HIT-MED Registry (I-HIT-MED)

Recruiting

500 enrolled

CNS

Ependymoma, Medulloblastoma, Pinealoma

NCT03750513 2025-11-13

LET Optimized IMPT in Treating Pediatric Patients With Ependymoma

Phase 1 Recruiting

48 enrolled

Ependymoma

NCT05278208 2025-10-20

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

Phase 1/2 Recruiting

65 enrolled

CNS

Diffuse Intrinsic Pontine Glioma, Ependymoma, Glioma, Medulloblastoma, Meningioma, Neoplasms, Germ Cell and Embryonal, Central Nervous System Neoplasms

NCT06779487 2025-04-11

BIO-RIN

Recruiting

200 enrolled

CNS

Brain Neoplasms, Ependymoma, Glioma, Medulloblastoma

NCT04648462 2024-11-26

Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncology

Recruiting

1,500 enrolled

CNS

Adenoma, Astrocytoma, Craniopharyngioma, Ependymoma, Hemangiopericytoma, Meningioma, Neurilemmoma, Oligodendroglioma, Germinoma, Ganglioglioma, Nerve Sheath Neoplasms, Optic Nerve Glioma

Clinical Trials

PNOC023

PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications

PNOC027

Natural History Study of Patients With Neurofibromatosis Type 2

MEMMAT

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment

Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

International HIT-MED Registry (I-HIT-MED)

LET Optimized IMPT in Treating Pediatric Patients With Ependymoma

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

BIO-RIN

Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncology