Clinical Trials

16 enrolled 13 charts

Esophageal Neoplasms

NCT01196390 2026-02-18

Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer

203 enrolled 22 charts

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT03993353 2026-02-12

Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer

GastrointestinalHead & Neck

7 enrolled 14 charts

Pyridoxine-dependent epilepsy, Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Esophageal Neoplasms, Head and Neck Neoplasms, Mouth Neoplasms, Neoplasm Metastasis, Neoplasms

NCT03008278 2026-02-03

Olaparib and Ramucirumab in Treating Patients With Metastatic or Locally Recurrent Gastric or Gastroesophageal Junction Cancer That Cannot Be Removed by Surgery

51 enrolled 20 charts

Esophageal Neoplasms, Stomach Neoplasms

NCT04505553 2026-01-21

Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer

EndocrineGastrointestinalNET

78 enrolled 14 charts

Gastro-enteropancreatic neuroendocrine tumor, Anus Neoplasms, Appendiceal Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Carcinoma, Hepatocellular, Adenoma, Islet Cell, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT03611309 2026-01-08

PERIOP-PC

379 enrolled 15 charts

Esophageal Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT06129487 2025-11-14

Evaluations of Alcohol Warning Labels

GastrointestinalHead & Neck

1,053 enrolled 15 charts

Alcohol Drinking, Esophageal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms

NCT01191697 2025-11-03

CAPOX, Bevacizumab and Trastuzumab for Patients With HER2-Positive Metastatic Esophagogastric Cancer

37 enrolled 11 charts

Esophageal Neoplasms, Stomach Neoplasms

NCT04526886 2025-10-06

Clinical Trial of a Novel Dose Adjustment Algorithm for Preventing Cytopenia-Related Delays During FOLFOX Chemotherapy

Classical hematologyGastrointestinal

52 enrolled 8 charts

Appendiceal Neoplasms, Esophageal Neoplasms, Neutropenia, Stomach Neoplasms, Thrombocytopenia, Colorectal Neoplasms

NCT00924027 2025-09-05

A Study of Patients Receiving High-Dose Rate Brachytherapy

GastrointestinalGenitourinaryGynecologic

43 enrolled 13 charts

Biliary Tract Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms

NCT00680901 2025-08-07

LOGiC - Lapatinib Optimization Study in ErbB2 (HER2) Positive Gastric Cancer: A Phase III Global, Blinded Study Designed to Evaluate Clinical Endpoints and Safety of Chemotherapy Plus Lapatinib

545 enrolled 24 charts

Esophageal Neoplasms, Neoplasm Metastasis, Neoplasms

NCT04068896 2025-05-29

Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

89 enrolled 21 charts

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT00357682 2025-05-01

AspECT

GastrointestinalOther neoplasm

2,557 enrolled 17 charts

Barrett Esophagus, Esophageal Neoplasms, Precancerous Conditions

NCT02689284 2025-03-17

Combination Margetuximab and Pembrolizumab for Advanced, Metastatic HER2(+) Gastric or Gastroesophageal Junction Cancer

95 enrolled 26 charts

Esophageal Neoplasms, Stomach Neoplasms

NCT02349412 2025-02-07

Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family Caregivers

GastrointestinalOther solid neoplasmThoracic

405 enrolled 11 charts

Mesothelioma, Malignant, Anxiety Disorders, Bile Duct Neoplasms, Carcinoma, Non-Small-Cell Lung, Depression, Esophageal Neoplasms, Liver Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Small Cell Lung Carcinoma

NCT03154190 2025-01-24

Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer

BreastDermatologicGastrointestinalGenitourinaryGynecologicMyeloidOther hematologic neoplasmSarcomaThoracic

128 enrolled 24 charts

Urinary Bladder Neoplasms, Bone Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Esophageal Neoplasms, Melanoma, Myelodysplastic Syndromes, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Sarcoma, Stomach Neoplasms, Leukemia, Myeloid, Acute, Disease Progression, Triple Negative Breast Neoplasms

NCT03474640 2024-11-22

Safety, Tolerability and Pharmacokinetics of an Anti-PD-1 Monoclonal Antibody in Subjects With Advanced Malignancies

GastrointestinalHead & NeckSarcoma

184 enrolled 20 charts

Nasopharyngeal Carcinoma, Chondrosarcoma, Esophageal Neoplasms, Carcinoma, Hepatocellular, Sarcoma, Stomach Neoplasms

NCT03189719 2024-10-15

KEYNOTE-590

749 enrolled 40 charts 1 FDA

Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Neoplasms

NCT03641547 2024-07-18

CHARIOT

36 enrolled 24 charts

Adenocarcinoma Of Esophagus, Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT02318329 2024-06-04

Open-Label, Dose-Finding Study Evaluating Safety and PK of FPA144 in Patients With Advanced Solid Tumors

GastrointestinalGenitourinary

79 enrolled 21 charts

Urinary Bladder Neoplasms, Esophageal Neoplasms, Stomach Neoplasms

NCT01941316 2024-05-09

Study of Carfilzomib With Irinotecan in Irinotecan-Sensitive Malignancies and Small Cell Lung Cancer Patients

GastrointestinalGynecologicThoracic

78 enrolled 15 charts

Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Ovarian Neoplasms, Stomach Neoplasms, Small Cell Lung Carcinoma

NCT02735239 2024-03-22

Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Oesophageal Cancer

73 enrolled 18 charts

Adenocarcinoma Of Esophagus, Diabetes Mellitus, Insulin-Dependent, 12, Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT03196232 2024-01-23

Epacadostat and Pembrolizumab in Treating Patients With Metastatic or Unresectable Gastroesophageal Junction or Gastric Cancer

3 enrolled 12 charts

Esophageal Neoplasms, Stomach Neoplasms

NCT03099382 2024-01-22

Study of SHR-1210 Versus Investigator's Choice of Chemotherapy for Participants With Advanced Esophageal Cancer

457 enrolled 9 charts

Esophageal Neoplasms

NCT02609425 2023-11-24

Intrathoracic Esophagogastric Anastomosis After Robot Assisted Minimally Invasive Esophagectomy Using STRATAFIX

Completed

30 enrolled 5 charts

Esophageal Neoplasms

NCT01522768 2023-11-01

Afatinib and Paclitaxel in Patients With Advanced HER2-Positive Trastuzumab-Refractory Advanced Esophagogastric Cancer

42 enrolled 9 charts

Esophageal Neoplasms, Stomach Neoplasms

NCT01401907 2023-10-19

Early Palliative Care in Advanced Lung and Gastrointestinal Malignancies

GastrointestinalOther solid neoplasmThoracic

351 enrolled 15 charts

Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Liver Neoplasms, Mesothelioma, Pancreatic Neoplasms, Stomach Neoplasms, Small Cell Lung Carcinoma

NCT02639065 2023-09-25

A Study of Durvalumab (MEDI4736) in Esophageal Cancer

39 enrolled 12 charts

Esophageal Neoplasms

NCT02971956 2023-09-21

Pembrolizumab in Refractory Advanced Esophageal Cancer

49 enrolled 10 charts

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT00063986 2023-06-29

Esophagectomy in Treating Patients With High-Grade Dysplasia of the Esophagus or Stage I, Stage II, or Stage III Esophageal Cancer

110 enrolled 13 charts

Esophageal Neoplasms

NCT00033657 2023-06-28

Radiation Therapy and Chemotherapy Before and After Surgery in Treating Patients With Esophageal Cancer

97 enrolled 9 charts

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT01333033 2023-04-13

PET Scan Imaging in Assessing Response in Patients With Esophageal Cancer Receiving Combination Chemotherapy

257 enrolled 13 charts

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT03933449 2023-03-29

KEYNOTE-181

123 enrolled 25 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Neoplasms

NCT02954536 2023-03-16

Phase II Trial of Pembrolizumab With Trastuzumab and Chemotherapy in Advanced HER2 Positive Esophagogastric (EG) Cancer

37 enrolled 8 charts

Esophageal Neoplasms, Stomach Neoplasms

NCT02564263 2023-03-13

KEYNOTE-181

628 enrolled 27 charts 1 FDA

Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Neoplasms

NCT02965976 2023-02-16

Botulinum Toxin Type A in Preventing Complications After Surgery in Patients With Esophageal Cancer

33 enrolled 17 charts

Esophageal Neoplasms

NCT00911820 2022-11-08

Cisplatin, Irinotecan and Bevacizumab (PCA) Versus Docetaxel, Cisplatin, Irinotecan and Bevacizumab (TPCA) in Metastatic Esophageal and Gastric Cancer

88 enrolled 14 charts

Esophageal Neoplasms, Stomach Neoplasms

NCT00623831 2022-10-25

A Phase 1 Study of Mixed Bacteria Vaccine (MBV) in Patients With Tumors Expressing NY-ESO-1 Antigen

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcoma

17 enrolled 14 charts

Breast Neoplasms, Carcinoma, Transitional Cell, Esophageal Neoplasms, Head and Neck Neoplasms, Melanoma, Ovarian Neoplasms, Prostatic Neoplasms, Sarcoma, Gastrointestinal Stromal Tumors

NCT02489422 2022-10-14

PRO-YOU

44 enrolled 28 charts

Anus Neoplasms, Appendiceal Neoplasms, Biliary Tract Neoplasms, Colonic Neoplasms, Depression, Esophageal Neoplasms, Fatigue, Gallbladder Neoplasms, Liver Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT03241173 2022-09-27

A Study Exploring the Safety and Efficacy of INCAGN01949 in Combination With Immune Therapies in Advanced or Metastatic Malignancies

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

52 enrolled 25 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Ovarian Neoplasms, Stomach Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT02559687 2022-09-14

KEYNOTE-180

121 enrolled 14 charts 1 FDA

Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Neoplasms

NCT01212822 2022-09-07

Bevacizumab and Combination Chemotherapy Before Surgery in Treating Patients With Locally Advanced Esophageal or Stomach Cancer

20 enrolled 10 charts

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms, Stomach Neoplasms

NCT02569242 2022-07-06

Study of Nivolumab in Unresectable Advanced or Recurrent Esophageal Cancer

419 enrolled 20 charts 2 FDA

Esophageal Neoplasms

NCT00655876 2022-06-14

Paclitaxel, Cisplatin, and Radiation Therapy With or Without Cetuximab in Treating Patients With Locally Advanced Esophageal Cancer

344 enrolled 11 charts

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT03335813 2022-06-09

Endoesophageal Brachytherapy for Patients With Esophageal Cancer

7 enrolled 18 charts

Esophageal Neoplasms

NCT02729753 2022-04-22

Clinical Study to Evaluate CryoBalloon™ Full and Swipe Ablation Systems for Ablation of Human Esophageal Epithelium

10 enrolled 8 charts

Esophageal Neoplasms

NCT00393068 2022-03-02

Chemotherapy, Radiation Therapy and Immunotherapy Prior to Surgery in Operable Esophageal Cancer

62 enrolled 8 charts

684,815 enrolled 6 charts

Esophageal Neoplasms

NCT01077817 2022-02-03

Observational Study of Incidence Rates of Esophageal Cancer in Women Taking Medications for the Prevention or Treatment of Osteoporosis (MK-0217A-352)

Completed

Adenocarcinoma, Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT02001623 2021-12-29

Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid Tumors

GastrointestinalGenitourinaryGynecologicHead & Neck

195 enrolled 51 charts

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms

NCT00193128 2021-11-24

Preoperative Therapy With Oxaliplatin/Docetaxel/Capecitabine and Radiation in Resectable Esophagus Cancer

59 enrolled 8 charts