Clinical Trials

Phase 3 Active not recruiting

Esophageal Neoplasms

NCT07306663 2025-12-29

ESO-Nanjing7

242 enrolled

Esophageal Neoplasms

NCT02297217 2025-12-16

PaRCUS

Phase 2 Recruiting

50 enrolled

Phase 2 Active not recruiting

Esophageal Neoplasms

NCT03110926 2025-09-12

Induction Chemotherapy for Locally Advanced Esophageal Cancer

40 enrolled

Phase 1 Active not recruiting

Esophageal Neoplasms

NCT04046575 2025-07-11

Radiation Dose Intensification With Accelerated Hypofractionated Intensity Modulated Radiation Therapy and Concurrent Carboplatin and Paclitaxel for Inoperable Esophageal Cancer

12 enrolled

Phase 1 Active not recruiting

Esophageal Neoplasms

NCT03044613 2025-03-06

Nivolumab +/- Relatlimab Prior to Chemoradiation With II/III Gastro/Esophageal Cancer

32 enrolled

Esophageal Neoplasms, Stomach Neoplasms

NCT04481256 2024-07-26

TAPESTRY

Phase NA Recruiting

49 enrolled

Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT06084897 2024-06-14

Radiotherapy in Patients With Metastatic Esophageal Cancer Responding to PD-1 Inhibitor Plus Chemotherapy

Phase 2 Recruiting

120 enrolled

Phase 3 Active not recruiting

Esophageal Neoplasms

NCT02509286 2024-05-08

ESOPEC

438 enrolled

Adenocarcinoma Of Esophagus, Adenocarcinoma, Esophageal Neoplasms

NCT06403878 2024-05-08

Safety and Efficacy of Neoadjuvant Immunochemotherapy in Elderly Patients With Resectable Esophageal Cancer

Phase 2 Recruiting

68 enrolled

Esophageal Neoplasms

NCT02735239 2024-03-22

Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Oesophageal Cancer

Phase 1/2 Completed

73 enrolled 18 charts

Adenocarcinoma Of Esophagus, Diabetes Mellitus, Insulin-Dependent, 12, Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT02735057 2024-01-18

OSAGE

Phase 1/2 Recruiting

54 enrolled

Esophageal Neoplasms

NCT02037048 2024-01-08

FOLFOX-6 Induction Chemotherapy Followed by Esophagectomy and Post-operative Chemoradiotherapy in Patients With Esophageal Adenocarcinoma

Phase 2 Unknown

63 enrolled

Phase 2 Active not recruiting

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT04764227 2023-08-03

Phase II Study of Postoperative Concurrent Chemoradiotherapy for Esophageal Squamous Cell Carcinoma (ESO- Shanghai 17)

70 enrolled

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT03094884 2023-05-23

Pulsed Low Dose Rate Radiation With Concurrent Chemotherapy for Non-Small Cell Lung Cancer and Esophageal Cancer

Phase 1 Unknown

40 enrolled

GastrointestinalThoracic

Esophageal Neoplasms, Lung Neoplasms

NCT01333033 2023-04-13

PET Scan Imaging in Assessing Response in Patients With Esophageal Cancer Receiving Combination Chemotherapy

257 enrolled 13 charts

Phase 1/2 Active not recruiting

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT03544736 2023-03-22

Safety and Feasibility of Irradiation and Nivolumab in Esophageal Cancer (INEC)

30 enrolled

Esophageal Neoplasms

NCT05245760 2022-11-08

CRATER

Phase 2 Withdrawn

Esophageal Neoplasms

NCT05188313 2022-06-24

TRAP-2

Phase 3 Recruiting

376 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT00393068 2022-03-02

Chemotherapy, Radiation Therapy and Immunotherapy Prior to Surgery in Operable Esophageal Cancer

62 enrolled 8 charts

Esophageal Neoplasms

NCT03095209 2021-10-12

Observation Study of Patients With Non-Small Cell Lung Cancer and Esophageal Cancer Treated With Chemo-Radiation Followed by Surgery

Completed

6 enrolled

GastrointestinalThoracic

Esophageal Neoplasms, Lung Neoplasms

NCT01077999 2021-04-21

Chemoradiation and Panitumumab for Esophageal Cancer

78 enrolled

Adenocarcinoma, Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT01183559 2021-01-22

A Trial of ZD6474, Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiation Therapy Followed by Surgery

9 enrolled 10 charts

Esophageal Neoplasms, Stomach Neoplasms

NCT00006472 2020-08-18

Combination Chemotherapy Plus Radiation Therapy Followed By Surgery in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer

Phase 2 Terminated

4 enrolled

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT03087864 2020-05-11

PERFECT

40 enrolled

Esophageal Neoplasms

NCT00439608 2020-02-17

Cetuximab, Paclitaxel, Carboplatin & Radiation for Esoph, Gastroesoph & Gastric Cancer

60 enrolled 9 charts

Esophageal Neoplasms, Stomach Neoplasms

NCT02389751 2019-07-24

Ganetespib in Combination With Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Stage II-III Esophageal Cancer

3 enrolled

Esophageal Neoplasms

NCT01715233 2019-03-15

Phase II Study Using CHFR Methylation Status in Patients With Metastatic Esophageal, Gastroesophageal, Gastric Cancer.

27 enrolled 10 charts

Esophageal Neoplasms, Stomach Neoplasms

NCT02177552 2019-02-15

SEED

Phase 2 Unknown

98 enrolled

Esophageal Neoplasms, Stomach Neoplasms

NCT00107341 2016-12-13

Bortezomib, Paclitaxel, and Carboplatin in Treating Patients With Unresectable, Metastatic Cancer of the Esophagus or Gastroesophageal Junction

37 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT00022139 2016-12-07

Radiation Therapy and Paclitaxel, Carboplatin, and Fluorouracil Followed by Esophagectomy in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction

56 enrolled

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms, Stomach Neoplasms

NCT02598687 2016-04-21

Testing TH-302, in Combination With Preoperative Chemoradiotherapy, in Esophageal Cancer.

Phase 1 Withdrawn

Esophageal Neoplasms

NCT00130936 2016-02-15

Study of Epirubicin (Pharmorubicin®), Carboplatin (Paraplatin®) and Capecitabine (Xeloda®) (ECC) in the Treatment of Unresectable Locally Advanced or Metastatic Gastric/Gastroesophageal Junction Cancer With Pharmacogenetic Correlates

Phase 1/2 Terminated

50 enrolled

Esophageal Neoplasms, Neoplasms, Stomach Neoplasms

NCT00383266 2016-01-11

A Phase II Study of Pemetrexed and Carboplatin in the Treatment of Esophageal Cancer

Phase 2 Terminated

9 enrolled 8 charts

Esophageal Neoplasms

NCT02570893 2015-10-07

A Phase III Trail of Adjuvant Chemoradiotherapy Versus Adjuvant Radiotherapy in Esophageal Squamous Cell Carcinoma

Phase 3 Unknown

366 enrolled

Esophageal Neoplasms

NCT00002854 2015-08-26

High-Dose Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Advanced Cancer

BreastDermatologicGastrointestinalGenitourinaryGynecologicSarcoma

33 enrolled

Carcinoma, Ovarian Epithelial, Anus Neoplasms, Bile Duct Neoplasms, Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasms, Wilms Tumor, Pancreatic Neoplasms, Rectal Neoplasms, Sarcoma, Osteosarcoma, Stomach Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral

NCT00153881 2014-11-13

Docetaxel and Carboplatin Followed by Oral Capecitabine, Docetaxel and Radiation for Esophageal Cancer

44 enrolled

Esophageal Neoplasms

NCT00368329 2012-07-16

Phase I Dose Escalation of Stereotactic Radiosurgical Boost for Locally Advanced Esophageal Cancer

Phase 1 Terminated

4 enrolled

Adenocarcinoma, Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT00193141 2011-05-03

Chemotherapy With or Without Surgical Resection in Locally Advanced Esophageal Cancer

200 enrolled

Esophageal Neoplasms

NCT00066716 2009-12-08

Celecoxib, Paclitaxel, and Carboplatin in Treating Patients With Cancer of the Esophagus

39 enrolled

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT00139633 2005-08-31

Selective Dose Escalation for Esophageal Cancer

Phase 2 Unknown

25 enrolled