Clinical Trials

203 enrolled 22 charts

Phase 1 Active not recruiting

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT02213497 2026-01-08

Dose Escalation of Neoadjuvant Proton Beam Radiotherapy With Concurrent Chemotherapy in Locally Advanced Esophageal Cancer

30 enrolled

Esophageal Neoplasms

NCT02297217 2025-12-16

PaRCUS

50 enrolled

Esophageal Neoplasms

NCT03281369 2025-12-15

A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Cancer (G/GEJ) or Esophageal Cancer (Morpheus-Gastric and Esophageal Cancer)

Phase 1/2 Completed

214 enrolled

Phase 3 Not yet recruiting

Esophageal Neoplasms

NCT06914011 2025-12-03

MRD2START

172 enrolled

Esophageal Neoplasms

NCT06251973 2025-12-02

A Study of agenT-797 in Combination With Botensilimab, Balstilimab, Ramucirumab, and Paclitaxel for People With Esophageal, Gastric, or Gastro-esophageal Junction Cancer

37 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT01142388 2025-11-25

Paclitaxel With or Without Cixutumumab as Second-Line Therapy in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer

94 enrolled 8 charts

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT04540211 2025-10-28

SKYSCRAPER-08

461 enrolled

Esophageal Neoplasms

NCT06143748 2025-09-17

EC-CRT-006

46 enrolled

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT03110926 2025-09-12

Induction Chemotherapy for Locally Advanced Esophageal Cancer

40 enrolled

Esophageal Neoplasms

NCT05007106 2025-08-14

KEYVIBE-005

BreastGastrointestinalGenitourinaryGynecologicHead & Neck

613 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Ovarian Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma, Triple Negative Breast Neoplasms

NCT02013154 2025-08-03

P102

Phase 1 Completed

151 enrolled

Phase 1 Active not recruiting

Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT04046575 2025-07-11

Radiation Dose Intensification With Accelerated Hypofractionated Intensity Modulated Radiation Therapy and Concurrent Carboplatin and Paclitaxel for Inoperable Esophageal Cancer

12 enrolled

Esophageal Neoplasms

NCT05357846 2025-06-12

PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy Plus Surgery for Locally Advanced ESCC (NEOCRTEC2101)

Phase 3 Recruiting

422 enrolled

Phase 1 Active not recruiting

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT03044613 2025-03-06

Nivolumab +/- Relatlimab Prior to Chemoradiation With II/III Gastro/Esophageal Cancer

32 enrolled

Esophageal Neoplasms, Stomach Neoplasms

NCT05191667 2025-02-13

AN0025 and Chemoradiotherapy Combination in Esophageal Cancer

Phase 1 Suspended

32 enrolled

Phase 2 Not yet recruiting

Esophageal Neoplasms

NCT05628610 2024-08-13

Tislelizumab Combined With Chemotherapy or Radiotherapy in the Treatment of Advanced or Recurrent Metastatic Elderly Esophageal Cancer

130 enrolled

Esophageal Neoplasms

NCT04481256 2024-07-26

TAPESTRY

Phase NA Recruiting

49 enrolled

Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT06084897 2024-06-14

Radiotherapy in Patients With Metastatic Esophageal Cancer Responding to PD-1 Inhibitor Plus Chemotherapy

120 enrolled

GastrointestinalGynecologic

Esophageal Neoplasms

NCT05395910 2024-05-29

Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) and Electrostatic PIPAC (ePIPAC) With Paclitaxel In Patients With Peritoneal Carcinomatosis

Phase 1 Recruiting

36 enrolled

Esophageal Neoplasms, Peritoneal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT05490719 2024-05-21

A Phase II Study of CRT Combined With QL1706 in ESCC Patients

39 enrolled

Phase 3 Active not recruiting

Diabetes Mellitus, Insulin-Dependent, 12, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT02509286 2024-05-08

ESOPEC

438 enrolled

Adenocarcinoma Of Esophagus, Adenocarcinoma, Esophageal Neoplasms

NCT02735239 2024-03-22

Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Oesophageal Cancer

Phase 1/2 Completed

73 enrolled 18 charts

Adenocarcinoma Of Esophagus, Diabetes Mellitus, Insulin-Dependent, 12, Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT02735057 2024-01-18

OSAGE

Phase 1/2 Recruiting

54 enrolled

Esophageal Neoplasms

NCT02037048 2024-01-08

FOLFOX-6 Induction Chemotherapy Followed by Esophagectomy and Post-operative Chemoradiotherapy in Patients With Esophageal Adenocarcinoma

Phase 2 Unknown

63 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT02988921 2023-11-24

MRI and CT Simulation in the Evaluation of Tumor Response and Target Volume Definition for Esophageal or Esophagogastric Cancer Patients Undergoing Chemoradiotherapy

Phase NA Recruiting

300 enrolled

Esophageal Neoplasms

NCT01522768 2023-11-01

Afatinib and Paclitaxel in Patients With Advanced HER2-Positive Trastuzumab-Refractory Advanced Esophagogastric Cancer

42 enrolled 9 charts

Phase 2 Not yet recruiting

Esophageal Neoplasms, Stomach Neoplasms

NCT05996484 2023-08-21

Neoadjuvant Therapy of Anlotinib Combined With Toripalimab and Chemotherapy for Resectable Esophageal Carcinoma

25 enrolled

Esophageal Neoplasms

NCT04764227 2023-08-03

Phase II Study of Postoperative Concurrent Chemoradiotherapy for Esophageal Squamous Cell Carcinoma (ESO- Shanghai 17)

70 enrolled

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT00033657 2023-06-28

Radiation Therapy and Chemotherapy Before and After Surgery in Treating Patients With Esophageal Cancer

97 enrolled 9 charts

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT00003237 2023-06-22

Combination Chemotherapy After Surgery in Treating Patients With Cancer of the Esophagus or Stomach

55 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT03094884 2023-05-23

Pulsed Low Dose Rate Radiation With Concurrent Chemotherapy for Non-Small Cell Lung Cancer and Esophageal Cancer

Phase 1 Unknown

40 enrolled

GastrointestinalThoracic

Esophageal Neoplasms, Lung Neoplasms

NCT01333033 2023-04-13

PET Scan Imaging in Assessing Response in Patients With Esophageal Cancer Receiving Combination Chemotherapy

257 enrolled 13 charts

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT03933449 2023-03-29

KEYNOTE-181

123 enrolled 25 charts

Phase 1/2 Active not recruiting

Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Neoplasms

NCT03544736 2023-03-22

Safety and Feasibility of Irradiation and Nivolumab in Esophageal Cancer (INEC)

30 enrolled

Esophageal Neoplasms

NCT02564263 2023-03-13

KEYNOTE-181

628 enrolled 27 charts 1 FDA

Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Neoplasms

NCT05245760 2022-11-08

CRATER

Phase 2 Withdrawn

Esophageal Neoplasms

NCT01726452 2022-09-30

NEOadjuvant Trial in Adenocarcinoma of the oEsophagus and oesophagoGastric Junction International Study (Neo-AEGIS)

377 enrolled

Esophageal Neoplasms

NCT05476380 2022-07-27

Neoadjuvant Therapy of Camrelizumab Combined With Chemotherapy for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma

Phase 2 Unknown

39 enrolled

Esophageal Neoplasms

NCT02569242 2022-07-06

Study of Nivolumab in Unresectable Advanced or Recurrent Esophageal Cancer

419 enrolled 20 charts 2 FDA

Esophageal Neoplasms

NCT05188313 2022-06-24

TRAP-2

Phase 3 Recruiting

376 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT00655876 2022-06-14

Paclitaxel, Cisplatin, and Radiation Therapy With or Without Cetuximab in Treating Patients With Locally Advanced Esophageal Cancer

344 enrolled 11 charts

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT00393068 2022-03-02

Chemotherapy, Radiation Therapy and Immunotherapy Prior to Surgery in Operable Esophageal Cancer

62 enrolled 8 charts

Esophageal Neoplasms

NCT02970539 2022-02-16

Ph1b Study of Oraxol in Comb. w. Ramucirumab in Patients w. Gastric, Gastro-esophageal, or Esophageal Cancers

Phase 1 Unknown

36 enrolled

Esophageal Neoplasms, Stomach Neoplasms

NCT04426955 2021-09-16

Study of Camrelizumab (SHR-1210) in Combination With Concurrent Chemoradiotherapy in Locally Advanced Esophageal Cancer

Phase 3 Unknown

396 enrolled