Clinical Trials Browser

Interventional × Esophageal Neoplasms × Radiation × Clear all

NCT01196390 2026-02-18

Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer

Phase 3 Completed

203 enrolled 22 charts

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT07038629 2026-01-07

Chemoradiation Plus Iparomlimab Consolidation in Older With ESCC

Phase 2 Recruiting

Gastrointestinal

Esophageal Neoplasms

NCT03161522 2025-10-23

Chemotherapy With or Without Radiation or Surgery in Treating Participants With Oligometastatic Esophageal or Gastric Cancer

Phase 2 Recruiting

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT00924027 2025-09-05

A Study of Patients Receiving High-Dose Rate Brachytherapy

Phase 2 Completed

43 enrolled 13 charts

GastrointestinalGenitourinaryGynecologic

Biliary Tract Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms

NCT07046221 2025-07-20

Tislelizumab Combined With Chemotherapy for Resectable Esophageal Squamous Cell Carcinoma Followed by CRT or Surgery

Phase 2 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT06906887 2025-06-29

PULSO Trial: Pulsed Low-Dose-Rate (PLDR) Radiation Chemoradiation (CRT) vs. Standard CRT for Esophageal Cancer

Phase 2 Recruiting

Gastrointestinal

Esophageal Neoplasms, Esophagitis

NCT04846309 2025-05-07

PIONEER

Phase 1 Recruiting

Gastrointestinal

Esophageal Neoplasms

NCT03044613 2025-03-06

Nivolumab +/- Relatlimab Prior to Chemoradiation With II/III Gastro/Esophageal Cancer

Phase 1 Active not recruiting

Gastrointestinal

Esophageal Neoplasms, Stomach Neoplasms

NCT05628610 2024-08-13

Tislelizumab Combined With Chemotherapy or Radiotherapy in the Treatment of Advanced or Recurrent Metastatic Elderly Esophageal Cancer

Phase 2 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT06086457 2024-07-16

PD-1 Inhibitor Plus Chemotherapy With or Without Radiotherapy in Patients With Metastatic Esophageal Cancer

Phase 3 Recruiting

Gastrointestinal

Esophageal Neoplasms

NCT05490719 2024-05-21

A Phase II Study of CRT Combined With QL1706 in ESCC Patients

Phase 2 Recruiting

Gastrointestinal

Diabetes Mellitus, Insulin-Dependent, 12, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT02735239 2024-03-22

Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Oesophageal Cancer

Phase 1/2 Completed

73 enrolled 18 charts

Gastrointestinal

Adenocarcinoma Of Esophagus, Diabetes Mellitus, Insulin-Dependent, 12, Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT03132922 2024-01-22

MAGE-A4ᶜ¹º³²T for Multi-Tumor

Phase 1 Active not recruiting

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Adenocarcinoma, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Head and Neck Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Sarcoma, Stomach Neoplasms, Sarcoma, Synovial, Liposarcoma, Myxoid

NCT02465736 2024-01-16

Study of Docetaxel or Vinorelbine Plus Cisplatin in Neoadjuvant Chemoradiotherapy for Esophageal Cancer (NEOCRTEC308)

Phase 3 Unknown

Gastrointestinal

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT02037048 2024-01-08

FOLFOX-6 Induction Chemotherapy Followed by Esophagectomy and Post-operative Chemoradiotherapy in Patients With Esophageal Adenocarcinoma

Phase 2 Unknown

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT01307956 2023-10-26

Panitumumab, Combination Chemotherapy, & Radiation Therapy in Esophageal or Gastroesophageal Junction Cancer

Phase 2 Terminated

11 enrolled 11 charts

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT05624099 2023-10-19

Camrelizumab Combined With Chemoradiotherapy in Advanced Esophageal Cancer.

Phase 2 Recruiting

Gastrointestinal

Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms

NCT02716688 2023-09-22

S-1 and Radiotherapy for Elderly Esophageal Cancer Patients

Phase 2 Withdrawn

Gastrointestinal

Esophageal Neoplasms

NCT03094884 2023-05-23

Pulsed Low Dose Rate Radiation With Concurrent Chemotherapy for Non-Small Cell Lung Cancer and Esophageal Cancer

Phase 1 Unknown

GastrointestinalThoracic

Esophageal Neoplasms, Lung Neoplasms

NCT05174117 2021-12-30

Influence of Different Light Dose on the Adverse Effect of Swallowing for Esophageal Carcinoma

Phase NA Unknown

Gastrointestinal

Esophageal Neoplasms

NCT05007145 2021-12-21

REVO

Phase 2 Unknown

Gastrointestinal

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT04426955 2021-09-16

Study of Camrelizumab (SHR-1210) in Combination With Concurrent Chemoradiotherapy in Locally Advanced Esophageal Cancer

Phase 3 Unknown

Gastrointestinal

Esophageal Neoplasms

NCT03187314 2020-08-17

Combination of Radiation Therapy and Anti-PD-1 Antibody SHR-1210 in Treating Patients With Esophageal Cancer

Phase 2 Completed

Gastrointestinal

Esophageal Squamous Cell Carcinoma, Esophageal Diseases, Esophageal Neoplasms

NCT02403531 2020-06-02

Induction Chemotherapy Followed by Chemoradiotherapy in Esophageal Cancer

Phase 2 Completed

Gastrointestinal

Esophageal Neoplasms, Neoplasms

NCT01787006 2020-03-10

Definitive Radiochemotherapy Plus/Minus Cetuximab in Unresectable Locally Advanced Esophageal Cancer

Phase 2 Completed

74 enrolled 24 charts

Gastrointestinal

Esophageal Neoplasms

NCT00522795 2020-02-17

Neoadjuvant Paclitaxel Poliglumex, Cisplatin and Radiation for Esophageal Cancer: A Phase II Trial (CTI#X64001)

Phase 2 Completed

40 enrolled 7 charts

Gastrointestinal

Esophageal Neoplasms

NCT02389751 2019-07-24

Ganetespib in Combination With Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Stage II-III Esophageal Cancer

Phase 1 Completed

Gastrointestinal

Esophageal Neoplasms

NCT03220009 2018-10-03

Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in Treating Patients With High Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma

Phase 2 Withdrawn

DermatologicGastrointestinalGynecologic

Uterine Cervical Neoplasms, Esophageal Neoplasms, Melanoma, Vaginal Neoplasms, Vulvar Neoplasms

NCT03213054 2018-09-26

A Study of OBP-301 With Radiation Therapy in Patients With Esophageal Cancer

Phase 1 Unknown

Gastrointestinal

Esophageal Neoplasms

NCT01561014 2018-07-02

Oxaliplatin, Fluorouracil, Erlotinib Hydrochloride, and Radiation Therapy Before Surgery and Erlotinib Hydrochloride After Surgery in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction

Phase 1 Completed

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms, Stomach Neoplasms

NCT00316862 2018-05-08

Cisplatin, Irinotecan, and Radiation Therapy in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer That Can Be Removed By Surgery

Phase 2 Completed

82 enrolled 9 charts

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT02446574 2017-10-24

Postoperative Chemoradiation in Patients With Node-positive Esophageal Squamous Cell Carcinoma

Phase 1/2 Completed

Gastrointestinal

Esophageal Neoplasms

NCT00193882 2017-07-12

Advanced Oesophageal Cancer Study to Compare Quality of Life and Palliation of Dysphagia.

Phase 3 Completed

Gastrointestinal

Deglutition Disorders, Esophageal Neoplasms

NCT00400114 2017-05-08

Sutent Following Chemotherapy, Radiation and Surgery For Resectable Esophageal Cancer

Phase 2 Completed

Gastrointestinal

Esophageal Neoplasms, Neoplasms

NCT00176800 2016-08-22

Chemoradiation and Tetrathiomolybdate (TM) in Patients With Esophageal Carcinoma

Phase 2 Completed

69 enrolled 7 charts

Gastrointestinal

Esophageal Neoplasms

NCT02461043 2015-09-01

Adjuvant Chemotherapy With Paclitaxel and Cisplatin in Lymph Node-Positive Adjuvant Chemotherapy in the Treatment of the Lymph Node Positive Thoracic Esophageal Squamous Cell Carcinoma

Phase 3 Unknown

Gastrointestinal

Esophageal Neoplasms

NCT01937208 2013-09-09

Comparable Study of Different Radiation Dose in Esophageal Carcinoma

Phase 3 Unknown

Gastrointestinal

Esophageal Neoplasms

NCT00520091 2012-05-18

Irinotecan, Cisplatin, and Radiation Therapy With or Without Celecoxib in Treating Patients With Stage II, Stage III, or Stage IV Esophageal Cancer

Phase 2 Completed

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT00815308 2011-02-08

EXCEL

Phase 2 Completed

55 enrolled 9 charts

Gastrointestinal

Esophageal Neoplasms

NCT00230451 2010-01-15

Pre-operative Chemotherapy and Radiation Therapy for Esophageal Carcinoma

Phase 2 Completed

Gastrointestinal

Esophageal Neoplasms

NCT00197444 2009-02-20

Low-Dose Nedaplatin (CDGP:Cis-Diammine-Glycolatoplatinum)/5-FU Combined With Radiation for Esophageal Cancer

Phase 2 Completed

Gastrointestinal

Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT00139633 2005-08-31

Selective Dose Escalation for Esophageal Cancer

Phase 2 Unknown

Gastrointestinal

Esophageal Neoplasms